GEM Project

🌟 Honored to have my poster selected as a Poster of Distinction at #CDDW2026 on #DietaryFat, #AntiGMCSF autoantibodies, and #CrohnsDisease Grateful to contribute with the amazing @The_GEMProject team and mentors: Drs @TurpinWilliams, @KenCroitoru, @SunHoLee15, at @SinaiHealth

The GEM Project team would like to congratulate @Jeongseok_Kim_ for his award for best abstract at #CDDWCLM2026! Check out his abstract here academic.oup.com/jcag/article/9…

The Gem Project Team was pleased to host @ProfWhelan for an insightful discussion into the current state of nutrition and its applications for IBD treatment and prevention. Thank you from all of us! @SinaiHealth @nutrisci_uoft @TurpinWilliams @KenCroitoru @SunHoLee15 @guthealthmd

📢 New in Gastroenterology from PROMISE group: Prediction and Prevention of Inflammatory Bowel Disease: A Call to Action Summarizing the key points from the May 2025 PROMISE Workshop @LopesScopes @khalili_MD @JeanFredericCo1 @KenCroitoru #IngaPeter pubmed.ncbi.nlm.nih.gov/41410638/

As the global incidence of inflammatory bowel disease (IBD) continues to rise, innovative strategies for early identification, prevention, and treatment are urgently needed. The PROMISE (PRediction and PRevention through Omics, Microbiome, Immune System, and Environment) Consortium, is a collaborative initiative led by @IcahnMountSinai, @SinaiHealth, and @MassGeneralNews. Supported by Helmsley, PROMISE aims to advance prediction, prevention, and improved outcomes for individuals at risk of developing IBD. Recently, PROMISE convened an international group of multidisciplinary experts, patient advocates, and individuals with IBD to create a roadmap toward prevention–focused strategies and interventions. The group also engaged with Dr. Carla Greenbaum, a leading expert in type 1 diabetes prevention, to explore cross-disease learnings. Their roadmap has now been published in Gastroenterology—marking an important step toward a future where IBD can be predicted and prevented. Read the full white paper: bit.ly/4j6GUoZ #CrohnsDisease #IBDResearch #Prevention

Happy Holidays from the GEM team! @SunHoLee15 @TurpinWilliams @KenCroitoru @RirongChen @BHUPESHTHAKUR30 @SinaiHealth @getgutsycanada

The Gem Team would like to celebrate our very own @TurpinWilliams for being 1 of 6 researchers appointed the position of Translational Research Scientist at LTRI! Williams is dedicated to bridging the gap between scientific discovery and clinical impact. sinaihealth.ca/news/sinai-hea…

🚨 Don't miss the latest article from @IMSMagazine covering @SunHoLee15 work with the GEM Project! With GEM’s unique dataset, Dr. Lee is helping to pave the way for precision medicine in IBD care and prevention. #PrecisionMedicine #IBDResearch imsmagazine.com/2025/01/27/gut…

Innovative research is essential for enhancing our understanding of Crohn’s disease and advancing the development of future preventative therapies. Helmsley supported the Genetic, Environmental, Microbial (GEM) Project , which aimed to predict an individual’s risk of developing Crohn’s disease, identify methods to prevent the disease before symptoms arise, and develop new treatments for those already affected. Recent studies from the GEM Project highlight the connection between environmental factors and healthy individuals with a family history of the condition. Read more about this work: bit.ly/3CK5NWp #CrohnsDisease #CrohnsAwareness

Congratulations to @AlexanderLuchak for successfully defending his PhD at the Department of Immunology @UofT! Alec's work in murine models of IBD has helped uncover potential mechanisms of IBD @KenCroitoru #DanaPhilpot @TheGEMProject @TurpinWilliams @Sunholee15 @BHUPESHTHAKUR30

Special seminar by @eytan_wine about “Gut microbes as a therapeutic target in IBD” @UofT_DoM @UofTGastroHep @SinaiHealth @KenCroitoru @TurpinWilliams @The_GEMProject @DrHArmstrong @annegri50789035 @guthealthmd @BHUPESHTHAKUR30

Excellent talk about Role of anti-microbial immunity in IBD @ivanvujk at the Biology of IBD Rounds @SinaiHealth @UofTGastroHep @KenCroitoru @TurpinWilliams @The_GEMProject @guthealthmd @laura_tee_mdgi @hsteinhart @vwaimeih @RichardYouWu @zanegallinger

Accelerating discovery to improve IBD care | Sinai Health sinaihealth.ca/foundation/our… @KenCroitoru @The_GEMProject @TurpinWilliams @guthealthmd @hsteinhart @laura_tee_mdgi @AnthonydeBuck @mantaj_brar @vwaimeih @zanegallinger @SinaiHealth @UofTGastroHep @chaim_bell @gingraslab1

You can also see the full manuscript here: cghjournal.org/article/S1542-…​ @MingyueXue @HaimLeiboIBD @SunHoLee15 @TurpinWilliams @KenCroitoru @getgutsycanada @HelmsleyTrust @JeanFredericCo1 @ManasiAgrawalMD @JoanaTo62523004 @DrTineJess"

Our findings linking microbial and environmental factors to CD risk were highlighted in a recent post from @GMFHx! Check out the link below: gutmicrobiotaforhealth.com/the-link-betwe…

See link below: cghjournal.org/article/S1542-… @MingyueXue @HaimLeiboIBD @Shao @DONGMEIzxc @SunHoLee15 @TurpinWilliams @KenCroitoru @RPanaccione @DiscoverIBD @marshllj @PaulMoayyedi @ibddocmaria @The_GEMProject @SinaiHealth @UofT_DoM @UofTGastroHep @getgutsycanada @HelmsleyTrust 8/8

We would like to thank our global team and our funding agencies. This study has been a great team effort, and we extend our gratitude to all participating sites and, of course, all participants. 7/8

New data from The GEM Project: led by @MingyueXue et al, published in CGH. This study identifies environmental variables associated with the future risk of Crohn’s Disease, the pathogenic mechanism of which can potentially be explained by some identified CD-risk biomarkers. 1/8