Tim Gollisch

65 years after Lettvin’s bug detector neurons in the frog retina, we revisit how the retina drives behavior—from reflexes to prey capture to brain-state modulation New review with @AnnaIntegrated & Serena Riccitelli in Annual Review of Vision Science 👇 tinyurl.com/ymp3vs4d

Excited to share out new paper in @NatureMedicine on base editing in the retina, @IOB_ch @BeamTx @semmelweishu nature.com/articles/s4159…. Watch the video here: iob.ch/news-view-all?…

read this great thread from superstar @RachanaDSomaiya describing our preprint with @shekharlab .

We have a new PhD position available. Please spread the word and retweet. The project will combine retina recordings, computational modeling, and optogenetics to help further develop vision restoration therapy. See here for more information: retina.uni-goettingen.de/join-the-lab/

The @ERC_Research has awarded a Consolidator Grant to the computer scientist and neuroscientist @sinzlab at the @uniGoettingen. 👉bernstein-network.de/en/newsroom/ne…

A very warm welcome to Oliver Barnstedt (@obarnstedt) joining @MBExC_de and @yourUMG as junior research group leader for "Multiscale Circuit Analysis". Have a great start!

@Li_Zhaoping @Nature What we see is that, across ganglion cell types, differences in activity correlations are not explained by differences in SNR. But would be interesting to check effects of, e.g., ambient light level on a given cell type.

@Li_Zhaoping @Nature Thanks! Yes, indeed, very nice and instructive videos. Have enjoyed watching a few of them already in the past and recommend them to students.

How natural stimuli lead to highly correlated ganglion cell activity in primate (marmoset) and mouse retina. Now out in @nature. nature.com/articles/s4158…

@StphTphsn1 @Nature Yes, subunits are key here. And contrast correlations do also affect (ON) midgets. But stim. correl. still decay with distance, and center-surround is there to mitigate effects of first-order correlations. So correl. are stronger in parasols where subunits are more important.

@TimGollisch @Nature (Just riffing at this point :)

Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵👇@cellhostmicrobe cell.com/cell-host-micr…

@StphTphsn1 @Nature And (OFF) midgets (in marmoset) seem to decorrelate just fine and pay no heed to the extra complications of natural scenes and higher-order correlations - at least to some approximation. 🙂

@StphTphsn1 @Nature Thanks, Stephane! Interesting thought. For parasols, correlations of spatial (high-frequency) contrast seem important, so that's indeed beyond pairwise pixel correlations. Whether the retina cannot or could, but doesn't, handle these... would be interesting to discuss.

@EmilieMaceLab @FrankFishLab @Nature Thanks, Emilie! 🙏

@TimGollisch @FrankFishLab @Nature Congrats Tim and the whole team!

@AmirmasoudAhma2 @Nature Thanks! 🙏

@TimGollisch @Nature Congratulations 🎉 An inspiring article that I really enjoyed reading

Thanks so much to Dimos Karamanlis for spearheading this, and thanks for a great team effort and for the funding support! @yourUMG @ERC_Research @dfg_public

More info about it in a thread at a different site.

If you need an inline perfusion heater, for example for your patch clamp rig, here is one for <30$. nature.com/articles/s4159…

New @bioRxiv #preprint with @chiara_fornetto and T Euler (who left X): biorxiv.org/content/10.110…

just published, happy to share eLife paper! doi.org/10.7554/eLife.… @eLife