Ting-Hsuan Chen

40 posts

Ting-Hsuan Chen

Ting-Hsuan Chen

@TingHsuanTHC

A transposon and epigenetics enthusiast in Plant and Food Research, NZ. A molecular and computational biologist in progress. PhD in Molecular Genetics.

Katılım Mart 2021
67 Takip Edilen32 Takipçiler
Ting-Hsuan Chen
Ting-Hsuan Chen@TingHsuanTHC·
My dear friends, I hope you'll enjoy the relaxing true-to-color time-lapse videos made by my husband and see the beauty of Taiwan from the mountains to cities and the seasides. You might find some lovely interesting details from them. 😉 youtube.com/playlist?list=…
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Ting-Hsuan Chen
Ting-Hsuan Chen@TingHsuanTHC·
@DamonLisch The assemblage of a few hundreds or thousands of dideoxyribonucleotides that is able to utilize the energy in the cell for self reproduction?
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Damon Lisch
Damon Lisch@DamonLisch·
Don't laugh. In the context of selfish DNA, I'm working on a definition of an individual organism. A discrete assemblage of genetic material and everything that requires it as a template to reproduce both itself and that genetic material?
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Damon Lisch
Damon Lisch@DamonLisch·
It's out! Theory and whole genome observations suggest that imprinting can be caused by insertion of TEs near genes. Here we silence de novo insertions to test the hypothesis experimentally. And it worked! Beautiful work by @MeixiaZhao and her students, esp @TongLi1112
Meixia Zhao@MeixiaZhao

We are excited to publish this work in @PlantPhys: doi.org/10.1093/plphys… with @DamonLisch. We created two potentially novel imprinted genes using Mutator transposons. There are no things that transposons can't do!

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Geitmann Lab
Geitmann Lab@GeitmannLab·
Before I cut it open: what do you reckon - does this almost perfect 90 degree differential color indicate that there are only 4 carpels in this apple? Does the hypanthium even align with carpel symmetry? So many questions!
Geitmann Lab tweet mediaGeitmann Lab tweet media
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Damon Lisch
Damon Lisch@DamonLisch·
@ThePlantCell @MaizeZynskiHI @ASPB I never really appreciated this before. We’ve observed that H3K27me3 mediates transgenerational silencing of Mu, which we thought was a special case, but what’s special is the resetting, not the heritability.
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Ting-Hsuan Chen
Ting-Hsuan Chen@TingHsuanTHC·
This is the type of research that I want to do and the hypotheses I want to test. 🙂 #sa0" target="_blank" rel="nofollow noopener">elifesciences.org/articles/81567…
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Ting-Hsuan Chen
Ting-Hsuan Chen@TingHsuanTHC·
Epialleles tend to associate with euchromatin, i.e. close to genic regions. However, epialleles associated with QTLs tend to be found in heterochromatin... And again, hypermethylated epialleles are more likely to associate with suppressive histone marks. nature.com/articles/s4146…
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Ting-Hsuan Chen
Ting-Hsuan Chen@TingHsuanTHC·
Not every epiallele has a direct or clear link with a causal genetic variation/mutation... #ref-CR11" target="_blank" rel="nofollow noopener">nature.com/articles/s4146…
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Ting-Hsuan Chen
Ting-Hsuan Chen@TingHsuanTHC·
Published in 2020. Looks like hypomethylated loci with permissive histone marks could be more stable (or last longer) than those without permissive histone marks... nature.com/articles/s4147…
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Rebecca Bloomer
Rebecca Bloomer@rhbloomer·
Come join the Annual Crops group at PFR! We're looking for a breeding/stats/quantitative genetics nerd to help support our arable/vegetable breeding programmes. Diverse projects, interesting crops and lovely colleagues (if I do say so myself 😜) careers.sciencenewzealand.org/jobdetails/aji…
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Genome Biology
Genome Biology@GenomeBiology·
The CRyPTIC consortium, Hunt, @ZaminIqbal & co present Minos, which combines output from different variant callers, to improve recall without loss of precision. Variants are confirmed by remapping reads to a graph of the combined variant call set. genomebiology.biomedcentral.com/articles/10.11…
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Keşfet

@suset_nz @CeciliaDNZ @ChenWu0306 @AThrimawithana @DamonLisch @MeixiaZhao @TongLi1112 @ThePlantCell