Alejandra Tomás Catalá

Amazing 2 days discussing the latest research at the @Soc_Endo Endocrine Metabolic GPCRs 2026 Meeting. Fantastic speakers from different angles: cell biology, physiology, drug discovery, etc. Icing on the cake was our very own PhD student Linda Wong winning the Best Poster Award!

Independent of weight loss, semaglutide (Ozempic) improves knee arthritis by cartilage restoration, in both the mouse model and a small randomized clinical trial @Cell_Metabolism cell.com/cell-metabolis…

Great opportunity to join us at Imperial - 20 Assistant Professor positions at the Faculty of Medicine have just been advertised. See below: imperial.ac.uk/jobs/search-jo…

@DUK_research Thanks to all the coauthors, particularly Denise Wootten and Giuseppe Deganutti for the cryo-EM and MD simulations, and the first author, former PhD student Liliane El Eid

Here is a link to an article about our study on the website of our funder @DUK_research: diabetes.org.uk/about-us/news-…

I am delighted to report that our latest paper has now been published in Science Advances: science.org/doi/10.1126/sc… In this study, we generated and characterised a humanised GLP‑1R mouse model carrying the gain‑of‑function A316T variant using CRISPR/Cas9 knock‑in technology.

📢We are excited to announce the initial speaker line-up for our #MembraneContactSites conference ⭐️Join us in Mexico in November 2026 to hear directly from the leading researchers in the field ➡️See who’s speaking and reserve your spot here! bit.ly/4acr3RR

Signaling Architecture of the Glucagon-Like Peptide-1 Receptor In this contribution to JCI’s Review Series on Clinical Innovation and Scientific Progress in #GLP-1 Medicine, Gregory O Austin & Alejandra Tomas @TomasLab_ICL @imperialcollege explore the spatiotemporal regulation of #GLP-1R signaling: doi.org/10.1172/JCI194…

🔬@ScienceMagazine A genetically encoded device for #transcriptome storage in mammalian cells | Science science.org/doi/10.1126/sc… @kevin921tw @insitubiology

Thrilled to share our newest method for transcriptome recording using TimeVault! science.org/doi/10.1126/sc…

Now online! Multimodal supramolecular targeting chimeras enable spatiotemporally resolved protein degradation in vivo dlvr.it/TQP8NQ

New Online! Heterogeneity, dynamics and organelle interactions of lipid droplets dlvr.it/TQMlT6

Thanks for including our work in this amazing JCI Series on GLP-1 jci.org/review_series/…

Extremely happy to be part of this amazing series jci.org/review_series/…

Our review is now out in JCI, where we discuss current evidence for the existence of GLP-1R–cAMP–PKA signalosomes at different subcellular locations, and the complexity of the GLP-1R spatiotemporal signaling architecture: jci.org/articles/view/…