Anthony Bauco

623 posts

Anthony Bauco

Anthony Bauco

@TonyB348

Katılım Kasım 2022
71 Takip Edilen39 Takipçiler
Anthony Bauco
Anthony Bauco@TonyB348·
@cremieuxrecueil There is a difference between intelligence and wisdom. They ARE correlated BUT they aren't the same. Wise people value all human beings and seek common ground.
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Anthony Bauco
Anthony Bauco@TonyB348·
@RonDeSantis The erosion needs some limit. 2% is reasonable because it almost guarantees that GDP growth exceeds it. Don't be like Biden. We need to reduce the M2 and deflate this bubble before it pops.
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SportsCenter
SportsCenter@SportsCenter·
WNBA HISTORY TO START THE 30TH SEASON‼️ The first season opener in league history where both teams scored 100 points 💪
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Ben Stiller
Ben Stiller@BenStiller·
KNICKS WIN
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WNBA@WNBA·
🚨 FINAL SCORE AND TOP PERFORMER 🚨 No easing in 😤 Paige Bueckers set the tone early in the @DallasWings preseason dub with all 20 of her points coming in the first half! 20 PTS | 3 AST | 4 3PM
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Anthony Bauco
Anthony Bauco@TonyB348·
@choppinfirewood @WNBA @DallasWings Paige's team won. Yeah, sure, every coach in the country has decided not to guard Paige Bueckers. Clark is easier to guard and turns the ball over more.
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Anthony Bauco
Anthony Bauco@TonyB348·
@ItalianMafiasip @WNBA @DallasWings Yeah, sure, every coach in the country has decided not to guard Paige Bueckers. Yeah, that must be it. It couldn't be that Clark is easier to guard and turns the ball over more. Nah.
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Italian Rebel
Italian Rebel@ItalianMafiasip·
@WNBA @DallasWings No one literally guarded her like they did to CC 🤣🤣. Paige was left open wide to shoot. That was pathetic.
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Anthony Bauco
Anthony Bauco@TonyB348·
@cremieuxrecueil Can you provide one chemical that you feel HAS been linked to cancer? As for this study, do you at least acknowledge the increase in colon cancer in that age group?
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Crémieux
Crémieux@cremieuxrecueil·
Just to be clear, this is completely wrong. To know that, you have to read the paper though. If you do read it, you'll notice a few things. Firstly, the design is non-causal. Discussion should stop there for most people. Secondly and more importantly, the study does not measure exposure to picloram or anything else at all. The associations are based on DNA methylation status. With an EWAS, you have all the caveats of a GWAS, but applied with (1) a more variable chemical modification of DNA; (2) less accurate assays; (3) with no control for underlying genetic variation; (4) smaller population sizes; (5) and very noisy imputation; (6) etc. etc. and so on and so forth. It's garbage. But, with all that, you then have to identify one or two single CpG islands across the whole genome from multiple independent studies (introducing batch effect problems) and then use those to determine someone's lifetime environmental exposure for a handful of cherry-picked variables. You have to be willing to take the unsupported assumption that this is even possible, and then report on the results, which is what this study did. The authors of the study even admit that they're not measuring exposure, but then, for some reason, they thought it was wise to introduce MORE noise into their findings by 'validation' through gene expression: "A high picloram MRS-GW score showed robust associations with EOCRC patients; however, validating whether the picloram MRS reflects actual picloram exposure is not feasible, as data on picloram-related DNA methylation effects are, to our knowledge, unavailable. Alternatively, we validated the pesticide MRSs using changes in gene expression induced by pesticides." A big problem with this is that this is not a valid validation method. DNA methylation and gene expression are often related in complex ways and the relationships tend to be tenuous. And the authors didn't even try to do this in the most credible way they could've. Instead, the authors used stem cells treated with various compounds and didn't even evaluate a direct relationship between DNA methylation marks and the associated genes. Instead, they calculated another score based on gene set enrichment—introducing MORE noise (GSEA is dependent on background, and functional enrichment tests should only be used to indicate possible pathways, not as explanations in themselves)—and correlated that score to their DNA methylation score. Lo and behold, a positive relationship of... a pretty small magnitude compared to what you'd expect if you actually saw 'validation' (just r = 0.44). All of this despite the fact that their validation test was *set up to guarantee a positive result* which is inherently meaningless with respect to the underlying biology of the thing. If you want to get at how good this validation test actually was, just look at the other results. For example, things which we know for a fact causally affect colorectal cancer—alcohol, BMI, obesity, smoking—were all either indicated as being unrelated or negatively related to it. The analysis didn't pick up on real signals from things that are actually more consistent in exposure, and are reliably measured. It failed with excellent positive controls! It's obviously not credible and nothing from it should be taken seriously. If I had to guess, this study was published as an activism piece and it will go on to be cited in court cases. Maybe it'll convince some dull-minded California or Hawaii jury to award billions to an aggrieved cancer patient for literally no reason. You can read it here: nature.com/articles/s4159…
The All-In Podcast@theallinpod

David Friedberg: Is This Pesticide Causing a Colon Cancer Spike in Young People? Colon cancer rates in people aged 15-39 are up 80% over the last 20 years. A team from the University of Barcelona might have figured out why: Picloram exposure

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Anthony Bauco
Anthony Bauco@TonyB348·
@HurtsSc4life Tessa should enter the portal for being recruited over. Or Jerzey should re-open her recruiting.
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Anthony Bauco
Anthony Bauco@TonyB348·
@MrBaddog7676 I have long said that Cashman has to be blackmailing the Steinbrenner family. He HAS to have dirt on them. Either that or Hal is as dumb as a box of rocks.
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BaddogSports
BaddogSports@MrBaddog7676·
Well. Yankees didn't hit any HRs last night, and not surprisingly, they got their ass kicked again. 320 million is criminal for this team. No left side of the infield, no catcher, lousy bullpen. 22 million for Trent Grisham. The Yankees are not a serious franchise
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Anthony Bauco
Anthony Bauco@TonyB348·
@MichaelPBento @JonathanCarmel5 He does have a point. As you said, fib works until it doesn't. But that usually signals a trend change. If we set a new ATH, it probably signals a trend reversal back to bull. I am hoping you are right and we resume the down trend without a new ATH. I was confident until today.
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Michael Bento
Michael Bento@MichaelPBento·
@JonathanCarmel5 All due respect you don't even follow me so you haven't see half of what I said. I said gamma levels could take us higher before we go lower. So either be honest or fuck off.
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Michael Bento
Michael Bento@MichaelPBento·
We got a double digit rally now like 2022, and we are now at the day after the 10DMA crossed back above the 200DMA, which in 2022 marked the top of the rally. In 2022 the RSI only got up to 64.99, today it is 66.74. 2022 topped after a 10 day winning streak, today is day 10 of the winning streak. 2022 the bounce topped out on a Tuesday, today is Tuesday. For all the 2025 analog people, that bounce from the bottom had several small pullbacks along the way up, we haven't had one, just like 2022. Is this time different? We'll see, but there's a lot of signs here that we are about to reverse. I'm sure I'll get plenty of low effort low IQ trolling comments on this, but I'm just providing data here, if you find the facts offensive that's on you.
Michael Bento tweet mediaMichael Bento tweet media
Michael Bento@MichaelPBento

March 2022 vs April 2026 Notice anything familiar? In 2022 after the initial breakdown of the 200DMA, the retest that cracked above it terminated the day after the 10DMA crossed back above the 200DMA. As long as we don't drop below 670 tomorrow, we will get the 10DMA crossing back above the 200DMA In 2022 that 11% rally was just as swift and steep as this one, everyone thought it was over and new ATH are coming, then we spent the next month going down -17.50%. Tomorrow we get a DeMark 9 Count Sell on the daily, and a 13 count sell on the 4H. RSI on every time frame below the daily is firmly in overbought territory. The call gamma magnet rolled off today. The downtrend is not invalidated unless we go above 693. Oil Shortages are starting to bite. All of these factors are why I still have a bearish outlook, however much I may have "missed" on the way up will be made 4 fold on the next leg down. Recency bias is a killer and everyone these days has the memory of a goldfish. Bottom line is unless we break above 693 I have no reason to be bullish in my 2 month time horizon.

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