
Trebak Lab
510 posts

Trebak Lab
@TrebakM
Professor of Pharmacology at Pitt. Investigator at the Vascular Medicine Institute. Interested in calcium signaling in physiology and disease.
Pennsylvania, USA Katılım Şubat 2019
401 Takip Edilen604 Takipçiler
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Small Correction. Had to delete &retweet. In final form. Response to 3 attack papers by (now former) EiC+EBMs on the same issue of their own journal. If we were wrong, 1 peer-reviewed data-driven paper in an independent journal would have been enough.
doi.org/10.1093/functi…
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Check out our new paper. A great collaboration between the Yule, Orlandi and Groblewski labs:physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

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Don’t miss this week’s new issue of #ScienceSignaling! New research shows how the loss of a calcium-sensing protein can exacerbate colorectal cancer growth, a preclinical study identifies dendritic scaffolds that shape the plasticity of synapses, and more. scim.ag/3FStmP1

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Loss of the calcium sensor #STIM2, but not of STIM1, worsens #ColorectalCancer growth and metastasis by boosting calcium ion content in the endoplasmic reticulum, remodeling mitochondria, and rewiring transcriptional activity. @TrebakM @Trayambak_P scim.ag/44v3O3E

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Great piece Manuel! Thank you!
Manuel F. Navedo@mf_navedo
🚨Editorial Alert🚨 Excited to share this editorial highlighting work from Magda Chrzanowska group in collab with @TrebakM Lab on the role of Rap1A in lung endothelium: ahajournals.org/doi/10.1161/AT… Collab with @Miguel_MartinAB & @MNCline @UCDavisHealth ahajournals.org/doi/10.1161/AT…
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We're excited to share that @APSPhysiology named @mf_navedo the 2025 recipient of the Robert M. Berne Distinguished Lectureship! This award is presented annually by the society’s Cardiovascular Section to an established leader in cardiovascular research. ucdavis.health/3BEi7qJ
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Paper alert!!! I am excited to share our recent work showing that phosphorylation of a single amino acid on the vascular Cav1.2 channel controls vascular reactivity & blood pressure in #hypertension. @ucdavis, @UCDavisHealth, @MCIPUCD, @UCDAVISPharmac1
ahajournals.org/doi/full/10.11…
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Check out our new study in collaboration with the Chrzanowska lab showing that Rap1A regulates CRAC channels in endothelial cells as a mean to control NFAT activation and vascular inflammation!
ahajournals.org/doi/pdf/10.116…
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Check out our new offering. Great collaboration with Serysheva lab. @Irina52948708
biorxiv.org/content/10.110…

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I hope labs in Africa will take advantage of this fantastic opportunity! 🔬🌍
Africa Microscopy Initiative@AMI_microscopy
📢GOOD NEWS! The Africa Microscopy Initiative, in partnership with @zeiss_micro will distribute refurbished research-grade light microscopes to African Scientists. Read more and APPLY: equipment.microscopy.africa/peer-apply Deadline: 13 September 2024
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Check out our new collaboration with @RoseEDixon1 from @ucd_physiology in @PNAS (pnas.org/doi/10.1073/pn…). We observed two modalities of beat-to-beat ATP fluctuations in ventricular myocytes based on SR-mitochondrial coupling strength. (1/2)
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Excited to announce the next #ECSwebinar on June 5th - 5 PM CET!🌟
We are looking forward to the talk of David Yule on modulation of IP3R regulation by Ca2+.
Find meeting link and updates on upcoming webinars here: #gid=0" target="_blank" rel="nofollow noopener">docs.google.com/spreadsheets/d…
@DavidYule64

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Great opportunity for a young assistant professor in a vibrant research environment at WCMQ and in Qatar to perform cutting edge cell biology research with translational potential. wcmq-academicpositions.odoo.com/jobs/detail/as…
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Check out this large collaborative effort re computational approach to drug design nature.com/articles/s4159…
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Congrats to @lfsantana68 for being named Distinguished Professor at UC-Davis, apparently the first Latino to receive this honor. Well deserved Fernando!
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Inflammation is a common feature of many diseases.
Murali Prakriya, PhD, discusses the evolution of this groundbreaking research in ion channels and his latest findings, which were published in @NatureComms, in this episode of our #BreakthroughsPodcast.
spr.ly/6018kJdyC
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Contact sites between organelles are critical for cell physiology. Interestingly during cell division the contacts between the ER and mitochondria expand with implications on cellular energetics. cell.com/iscience/fullt…
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