Very exciting! The first LRRK2 inhibitor-bound structures! Paving the way towards more tailored drug discovery in Parkinson's diesease. Great collaboration! Happy to be part of this. @ChasingKinases @aleschziner @MartaSanz3 @ASAP_Research @chatterjeedeep
Andres Leschziner@aleschziner
We report the first #cryoEM structures of #LRRK2 bound to type-1 and type-2 kinase inhibitors. Great team effort to advance Parkinson’s Disease therapeutics research! #StefanKnapp @ChasingKinases @Marta_Sanz3 @acvillagransu @DedererVerena @ASAP_Research biorxiv.org/content/10.110…
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