Deep Chatterjee retweetledi
Preprint from Dario Alessi lab identifying many new #LRRK2 variants linked to #Parkinson’s - some lying outside of the catalytic domain - that activate kinase activity. @ASAP_Research biorxiv.org/content/10.110…
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Deep Chatterjee
203 posts
Deep Chatterjee
@chatterjeedeep
Postdoc@SGC Frankfurt... kinase enthusiast.... focused on non-catalytic or scaffolding function of proteins...
Frankfurt on the Main, Germany Katılım Ocak 2010
66 Takip Edilen53 Takipçiler
Deep Chatterjee retweetledi
Great #LRRK2 Investigator Workshop with #TeamAlessi #TeamReckPeterson and #TeamDeCamilli @ASAP_Research We love talking science in person - thank you to everyone that contributed! #ASAPmeeting2022
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Deep Chatterjee retweetledi
Preprint from the Alessi lab identifying many new #LRRK2 variants linked to #Parkinsons - some lying outside of the catalytic domain - that activate kinase activity biorxiv.org/content/10.110…
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Deep Chatterjee retweetledi
The first datasets from our degradation proteomics initiative were sent out over the last few weeks!! 🎉
If you’re interested in free global proteomics screening of degraders for target ID and mapping please get in touch and I can provide further details.
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Deep Chatterjee retweetledi
Call for papers: submit your work on emerging high-throughput technologies for tool compound discovery/validation now!!!
We are interested in a range of topics, so check it out: liebertpub.com/doi/10.1089/ad…
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Deep Chatterjee retweetledi
Our new paper on mining the dark kinome with the software ProKinO is on #biorxiv. We've added a number of new tools into the ProKinO suite for mining data, including structural models generated via #AlphaFold2. #Bioinformatics #kinase #compchem #biochem
biorxiv.org/content/10.110…
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Deep Chatterjee retweetledi
Submitted required documents for 221g form 6 weeks ago and hoping to receive my B1 US visa, in order to participate @GordonConf on autophagy (march 19-25, 2022). Earnest request to @usconsfrankfurt, to expedite #221g processing. #crucialcareerdecision. Please retweet.
Frankfurt on the Main, Germany 🇩🇪 English
Deep Chatterjee retweetledi
Small molecule modulation of protein polymerization - a Viewpoint from Eric Fischer and myself now published in Chemical Society Reviews pubs.rsc.org/en/content/art…
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Deep Chatterjee retweetledi
Delighted to contribute to new study from @v_decesare @mrcppu describing robust mass spectrometry assays for measuring #Parkin activity offering exciting new screening platform for Parkin activators #Parkinsons #therapeutics biorxiv.org/content/10.110…
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Deep Chatterjee retweetledi
Are you curious about the function of DFCP1 in autophagy? Have a look at our latest preprint - we find that it is an ATPase involved in selective autophagy! @kschink @harald_stenmark @TerjeJohansen17 @VeijoS @CanCell_UiO @IkonenLab @tankiawee biorxiv.org/content/10.110…
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''Mother of Macrocycles''
drug hunter@drughunter_com
Why Merck’s PCSK9 Inhibitors Are a Big Deal | drughunter.com/molecules-of-t… Merck’s oral, macrocyclic PCSK9 inhibitors have already gotten quite a few votes for 2021’s “Molecule of the Year," w/ readers calling them "gamechangers" More details in our newly released slide deck
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Deep Chatterjee retweetledi
Have a look on our review about structural and pharmacological features of LIMKS! mdpi.com/2073-4409/11/1…
👏👍
@ChasingKinases @chatterjeedeep @MDPIOpenAccess @thesgcfrankfurt
__as_n_ Kinas_s@ChasingKinases
Please check out our review! 'Structural Aspects of #LIMK Regulation and Pharmacology' mdpi.com/2073-4409/11/1… Thanks everyone for your contributions @chatterjeedeep @VerenaD4 @thesgcfrankfurt @MDPIOpenAccess
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Deep Chatterjee retweetledi
Please retweet...
Join our team in sunny Frankfurt!
jobrxiv.org/job/sgc-frankf…
#protease #drugdiscovery #structuralbiology @gatesfoundation
@thesgcfrankfurt
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Deep Chatterjee retweetledi
Proud to share our work on the elusive structures of the HER2/HER3 heterocomplex. @JuraLab_UCSF @Nature @QBI_UCSF @UCSF nature.com/articles/s4158…
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Deep Chatterjee retweetledi
Our latest thoughts on #PINK1 and #Parkin in this mini review out today. sciencedirect.com/science/articl…
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@BorisFuertig I thought University is looking into this matter seriously....
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Deep Chatterjee retweetledi
Register now for the #Target2035 webinar on Sep 21, 2021 to learn about #drugdevelopment in #AlzheimersDisease within an #OpenScience framework. Hosted by Suzana Petanceska's @Alzheimers_NIH. Speakers from @Sagebio, @IUMedSchool, @UniofOxford
Target2035.net
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Deep Chatterjee retweetledi
Who in academia/charity wants *free* pure, active PKA catalytic subunit for #kinase assays etc? Based on @SigmaAldrich price, $5 million worth to freely distribute. Can't be arsed to start a company. Please RT if reagent sharing sounds up your alley. Many other #kinases too!
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Deep Chatterjee retweetledi
AlphaFold models of the 144 largest human proteins.
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Deep Chatterjee retweetledi
Just out! Our new preprint into human #PINK1 kinase activation based on @DeepMind #AlphaFold PINK1 structure models. Uncovering new mechanisms of #Parkinsons disease. 🙏 @mrcppu lab and collaborators from @Astbury_BSL @baylisslab @DZNE_en #TeamScience bit.ly/3DM5dn8
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