Vervoort Lab - Transcriptional Regulation

New preprint on technologies to scale up CRISPR screens. We use them to map 665,856 pairwise genetic perturbations and outline a path to comprehensive interaction mapping in human cells. We also introduce an approach for cloning lentiviral libraries with billions of elements.

A TAK1 cytokine toxicity checkpoint controls anti-cancer immunity: Cell Reports cell.com/cell-reports/f…

🚨Calling students! Join the Vervoort Lab @ WEHI for an Honours/PhD project using CRISPR screens + genomics to reveal new regulators of gene expression. Info: wehi.edu.au/project/uncove… 🧬 @WEHI_research

Our new paper is out on @MolecularCell !! We show that Integrator complex, is essential for RNA Polymerase II recruitment, pluripotency, and developmental gene regulation in mESCs. sciencedirect.com/science/articl… #StemCells #Transcription #DevelopmentalBiology #RNApolII

Now out in the July 10th issue of @CellCellPress LoxCode in vivo barcoding reveals epiblast clonal fate bias to fetal organs: Cell cell.com/cell/fulltext/…

Snow Medical is hiring… Program Manager - Translation linkedin.com/jobs/view/4260… Translation Manager linkedin.com/jobs/view/4260… Senior Scientist/Program Manager - cognition and brain health linkedin.com/jobs/view/4260… Biomedical Research Analyst linkedin.com/jobs/view/4260…

Australia completely lacks a dedicated training program for clinician scientists. With the vision and support of VMIAL @PeterMacCC is extremely proud to announce the first clinician-scientist fellowship. If you meet the eligibility criteria PLEASE APPLY! nature.com/naturecareers/…

🌏 Make your mark in Melbourne! 🌏 We are looking for innovative researchers to join WEHI as Laboratory Heads and help lead the next wave of biomedical discovery. For more information and to apply 👇 wehi.edu.au/careers/make-y…

Excited to share our latest pre-print identifying TAK1 as a tumour intrinsic checkpoint that limits CTL-derived cytokine-induced cell death and immunotherapy responses. Brilliant collaboration between @Kearney_Lab @ONJCRI and @Vervoort_Lab @WEHI_research. biorxiv.org/cgi/content/sh…

Australia has an “urgent and unparalleled opportunity to attract the smartest minds leaving the United States” —Academy President Prof Chennupati Jagadish AC theguardian.com/education/2025…

What happens when we embed smart minds within the Australian R&D system? When Professor Michelle Simmons AO FRS FAA FTSE decided to call Australia home, she seeded a 30-year development of quantum science that today sees Australia leading the race to develop the first quantum computer. When Professor Lidia Morawska FAA joined QUT, she gifted Australia world leading expertise in airborne transmission of disease that shaped the global response to COVID-19. Interested in building a profound and nation-building legacy? Partner with us on our Global Talent Attraction Program. science.org.au/news-and-event…

A post doc position is available in my lab @ONJCRI 🔬 If you are interested in investigating tumour immune escape using genomics and CRISPR please get in touch!!!

Our 2025 #SnowFellowship round is now open for applications! The Snow Fellowship provides emerging leaders the independence, funding and time to develop a bold research program, build their research team, and establish leadership experience. #SnowMedical snowmedical.org.au

@SnowMedical @gl_alisa @WEHI_research Huge congratulations to @SnowMedical @gl_alisa and @WEHI_research 🥳.

We’re thrilled to welcome our 14th Snow Fellow, Dr Alisa Glukhova @gl_alisa, a structural biologist from @WEHI_research. Alisa’s work focusses on how cells communicate and what happens when those signals go wrong, leading to diseases like cancer. snowmedical.org.au

To our fellow scientists in the USA — we see you, and we feel your pain. If you’re thinking about a change, consider Australia. Funding is tough everywhere, but here, at least, you’re wanted — and we’d be glad to have you. 🫶

We are looking for a talented postdoctoral bioinformatician ⁦@TheDawsonLab⁩ to work with us on single cell multiomics incorporating lineage tracing and spatial technologies- we specifically want someone curious, fearless with a licence to innovate!! nature.com/naturecareers/…

We are hiring! Here is your opportunity to work at the cutting edge of #cfDNA bioinformatics in Melbourne, Australia! If you (or someone you know) is interested, please apply below!

📢 World-leading Immunologists. The Nossal Endowed Chair of Immunology has just been announced @WEHI_research. This is your chance to move (or return) to Australia to do ground-breaking research and join a thriving environment for discovery and translation alumniglobal.com/job/the-sir-gu…

WEHI and @TheRMH are excited to announce Assoc Prof Edwin Hawkins and Dr Michael Christie have been appointed to lead the Colonial Foundation Diagnostics Centre – a pioneering research centre aiming to advance precision diagnosis for inflammatory disease. wehi.edu.au/news/visionary…