We just published our article on discovery of novel small-molecule ERBB4 agonists. nature.com/articles/s4146…
Thx to Gilles De Keulenaer, Eline Feyen, Julie Cools, Bo Goovaerts, and many others
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Vincent Segers
38 posts
Vincent Segers
@VincentSegers2
physician-scientist, cardiology
Antwerp, Belgium Katılım Mart 2019
66 Takip Edilen64 Takipçiler
Vincent Segers retweetledi
Excited by cardiac physiology? #escbasicscience #ewgcce
Dan Johnson@danmjohnson
The @escardio #EWGCCE Scientific Exchange grant scheme is now open! Are you an #EarlyCareer #Investigator interested in developing your cellular electrophysiology skillset and visiting another European Lab? Apply now for up to €2,500 to do so! tinyurl.com/4e8d4cv2
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Vincent Segers retweetledi
De universiteiten moeten meer focussen op hun kerntaak: kennis vergaren en doorgeven @Stijn_Baert standaard.be/cnt/dmf2024091…
Nederlands
Vincent Segers retweetledi
Case report: a diagnosis of left ventricular anterior free-wall rupture in a female patient with jaw pain, diagnosed with ST-elevation myocardial infarction, who developed sudden hemodynamic deterioration after administration of anticoagulant therapy. ja.ma/3Ze6zV6
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Vincent Segers retweetledi
@VincentSegers2 @UAntwerpen iBof colleagues at Antwerp erbb4 agonists in #hfref great job Julie cools
#ESCBasicScience @liberale_luca @C_Balbi90
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We participated in @AtomwiseInc #AIMS study published in @SciReports highlighting #AtomNet as a viable alternative to high-throughput screening! Read about the largest and most comprehensive virtual HTS campaign to date: atomwise.com/2024/04/02/pre… #drugdiscovery #AI #pharma #biotech
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Vincent Segers retweetledi
Everything you need to know about atrial myopathy, a comprehensive review by the amazing @michieltubeeckx
Basic Research in Cardiology@BasicResCardiol
Atrial myopathy and fibrillation. link.springer.com/article/10.100…
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Vincent Segers retweetledi
The gut Cholesin-GPR146 axis mediates the inhibitory effect of intestinal cholesterol absorption on hepatic #cholesterol synthesis @CellCellPress cell.com/cell/abstract/…
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Excellent study in Science Translational Medicine demonstrating that cardiac endothelial contribute to cardiac fibrosis, both directly by production of extracellular matrix and indirectly by activation of fibroblasts.
science.org/doi/10.1126/sc…
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Amazing study in JACC: Multiomics Analysis Provides Novel Pathways Related to Progression of Heart Failure. jacc.org/doi/10.1016/j.…
And guess what? The most important pathway discovered in this unbiased study is the neuregulin/ERBB pathway.
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Vincent Segers retweetledi
6) Analysis from LAAOS III shows LAA occlusion provides thromboembolism reduction in pts independent of OAC use.
Link: ahajournals.org/doi/abs/10.116…
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More evidence that cardiac remodeling induces tumor growth: Pressure Overload–Induced Cardiac Hypertrophy Stimulates Tumor Growth in Tumor-Prone ApcMin Mice | Circulation: Heart Failure ahajournals.org/doi/10.1161/CI…
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Vincent Segers retweetledi
🔓 FREE Article of the Week
Endothelial dysfunction at the cellular level in three dimensions: severity, acuteness, and distribution
@VincentSegers2, Tijs Bringmans, Gilles W. De Keulenaer
ow.ly/wErH50PvSYo
@UAntwerpen
#atherosclerosis #cancer #diabetes #heartfailure
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Ellegant paper describing a screening experiment for molecules that modulate cardiomyocyte relaxation, while at the same time identifying EGFR/IGF1R Signaling as a new pathway regulating cardiac relaxation. Circulation Research ahajournals.org/doi/abs/10.116…
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Vincent Segers retweetledi
LBBAP significantly reduced primary outcome of death or #heartfailure hospitalization compared to biventricular pacing in a large observational study of 1,778 patients. bit.ly/45kwURO
#JACC #LVEF #CardioTwitter @hisdoc1 @kennethellenbo1 @jerin3590 @Mishalmumtaz_
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Vincent Segers retweetledi
Check out the latest #JACCINT state-of-the-art review highlighting the key elements for a successful same-day discharge pathway across the spectrum of #coronary, #peripheral, and #structural interventions: bit.ly/3NVlyfh
#CathLab #CardioTwitter @tavrkapadia
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Vincent Segers retweetledi
Excited to join the team.
Must update this babyfaced picture. Working on aging remains a priority!
JMCC Plus@JMCCPlus
Next on #MeetTheEditors, we are pleased to introduce @roderick_cardio! Llew is #Professor at KU Leuven @leuvenresearch. His research interests include #epigenetics, excitation #transcription coupling and #EC coupling in cardiac disease.
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Recruited macrophages elicit atrial fibrillation | Science science.org/doi/10.1126/sc… Excellent study by Maarten Hulsmans and colleagues demonstrating the importance of recruited macrophages to development of Atrial fibrillation.
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Vincent Segers retweetledi
@AndreasGevaert @JACCJournals @ECraenenbroeck @martinbahls @ProfessorHalle @CERG_NTNU @C_VanDeHeyning @VincentSegers2 @lobkepype @HNSturkenboom Congratulations 🍾
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An argument to continue clopidogrel instead of aspirin monotherapy:
Aspirin vs. Clopidogrel for Chronic Maintenance Monotherapy after Percutaneous Coronary Intervention: the HOST-EXAM Extended Study ahajournals.org/doi/abs/10.116…
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