X David Li Lab
159 posts
X David Li Lab
@XDavidLiLab1
Professor in HKU Department of Chemistry，School of Biological Science and School of Biomedical Science. Epigenetics and Chemical Biology.
Hong Kong Katılım Şubat 2021
204 Takip Edilen671 Takipçiler
We have reported a series of first-in-class inhibitors for YEATS domain proteins since 2018, including an ENL inhibitor in 2018, an AF9 inhibitor in 2020, and now the first YEATS2 inhibitor. This work is now published in @nchembio
nature.com/articles/s4158…
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Tenure-Track Professoriate Position in Chemical Biology at The University of Hong Kong
nature.com/naturecareers/…
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@doc_jlmeier Oh, I miss this place! Last time being there was 2019.......
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Congrats to Shixian @Linlab_ZJU on this paradigm-shiftimg work. Unnatural amino acid incorporation using rare codons. Really COOL!!
Shixian Lin@Linlab_ZJU
🔊Check out our work in @ScienceMagazine. We identify a new weak point (TCG codon) in the codon table of mammalian cells and recode it into non-canonical amino acids (ncAAs) with impressive efficiency and selectivity. This strategy, rare codon recoding (RCR), is very different!
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A new application of photo-ANA to interrogate tissue-specific protein-protein interactions is now published in PNAS.
MACSPI enables tissue-selective proteomic and interactomic analyses in multicellular organisms | PNAS pnas.org/doi/10.1073/pn…
X David Li Lab@XDavidLiLab1
How long and how much it takes from idea to publication? Here is my tale of three molecules that I designed more than 11 years ago.
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I am honored to receive this recognition from HKU, where I studied and have served for more than 12 years😊
The University of Hong Kong@HKUniversity
Congrats to Prof David Li (@XDavidLiLab1) from @HKU_Chemistry and Prof Stephanie Ma (@stephaniema912) from @hkusbms on being awarded this year's #HKU Outstanding Researcher Award for their exceptional research accomplishments! 🎥youtube.com/watch?v=9g1axQ…
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nature.com/articles/s4158… Delighted to share our recent work. We developed an enhanced chemoproteomic workflow to determine PAL probe interaction sites in cells, enabling ID of diverse binding pockets, providing evidence of their chemical tractability & more w/@ForliLab & @bmsnews
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A Must-Read thoughtful and comprehensive review from my colleague Xuechen @LiXuechen_HKU, a Master of Chemical Protein Synthesis!!
Xuechen Li@LiXuechen_HKU
We put a lot of thinkings and efforts in this paper. Hope this will be useful to the peptide/protein chemistry community. "Precision in Protein Chemical Modification and Total Synthesis". authors.elsevier.com/a/1i8PB8jWHEHS…
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Reunion of Kapoor lab @KapoorLab_RU alumni @JeffTiLab @XDavidLiLab1 and collaborator @Hippo326 for hotpot in Hong Kong😁
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Great to visit @TheCrick institute for the first HKU-Crick symposium together with many colleagues from @hkusbms @hkumed @hku_science. As the only chemist in the symposium, I am glad to learn lots of new frontier biology.
Max Gutierrez@maxgabgut
Great to meet so many people from @hkumed @hkusbms - thanks for coming to visit @TheCrick
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This is very encouraging 😄! Indeed I put a lot of thinkings into this paper. Hopefully it is helpful to the community.#JACS
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I am very honored to receive 2024 Tetrahedron Young Investigator Award for Bioorganic and Medicinal Chemistry.
sciencedirect.com/journal/tetrah…
Thanks to @TetrahedronChem for recognizing our works, and continuous support from @hku_science and @HKU_Chemistry
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Punjab, Pakistan 🇵🇰 English
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