Liling Wan

(1/n) Excited to share our new preprint! We uncover that RNA actively promotes nucleation and function of pathogenic condensates, amplifying locus-specific oncogenic transcription and promoting tumorigenesis. #epigenetics #condensates #cancer #RNA biorxiv.org/content/10.110…

@RogerRogergr Awesome! Congrats to Haoyang!

Thrilled to announce that postdoc, Haoyang Jiang, has been awarded an NCI Pathway to Independence Award (K99/R00) for his project, "BLM-Driven Recombination at Alternative Lengthening of Telomeres and Non-Telomeric Sites." Congratulations Haoyang on this well deserved award!

@NilimeshDa6026 @MolecularCell @PennMedCSO @PennCancer @PennEpiInst Thanks! excellent point about potential roles of other charged proteins in the process; indeed, we have discussed this in the limitation section of the paper.

@LilingWanLab @MolecularCell @PennMedCSO @PennCancer @PennEpiInst Congratulations!! A fantastic paper. There were hints; but the data here make a very compelling case for nascent RNA. May be the only thing is an alternate is always possible through phosphorylation change of rna polymerase; but this is about as convincing as one can get 🎉

Excited to share that our preprint 'RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription' is now online @MolecularCell cell.com/molecular-cell… @PennMedCSO @PennCancer @PennEpiInst

@bloodgenes @MolecularCell @PennMedCSO @PennCancer @PennEpiInst Thanks Vijay!

@LilingWanLab @MolecularCell @PennMedCSO @PennCancer @PennEpiInst Congratulations, @LilingWanLab!!! Wow!! This is so fascinating!

@RongFan8 @MolecularCell @PennMedCSO @PennCancer @PennEpiInst Thanks Rong! Congrats to your recent papers too! You are on a roll!

@LilingWanLab @MolecularCell @PennMedCSO @PennCancer @PennEpiInst Congratulations Liling!! 👏👏

@iannisaifantis1 @MolecularCell @PennMedCSO @PennCancer @PennEpiInst Thanks Iannis! Hope all is well!

@LilingWanLab @MolecularCell @PennMedCSO @PennCancer @PennEpiInst that is fantastic Liling!!

Online Now: RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription dlvr.it/TT0yzt

@Mayr_Christine @KarunaMDPhD @CellCellPress Congratulations Christine! Very cool findings!

Finally out in @Cellcellpress! Proteins with long intrinsically disordered regions (IDRs) are prone to misfolding during protein synthesis. This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones. cell.com/cell/fulltext/…

@PeterLyLab @SJMorrison_ @CellCellPress Congrats Peter!!

Excited to share our latest paper, out today @CellCellPress. We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. (1/7) cell.com/cell/fulltext/…

@bloodgenes @Anders_S_Hansen @lvchosen1 @silvirouskin @Armstrong_dfci @CellPressNews @DanaFarberNews @DanaFarber @BroadMPG @broadinstitute @hhmi_science @BostonChildrens @GauravA_UK @guo_chunjie Congrats Vijay! So great to see this story out!

🚨 Excited to share a new paper in Cell! Human genetics led us to HOTSCRAMBL, a HOXA-locus lncRNA that regulates 🩸#stemcell self-renewal and HOXA9 splicing, with implications for AML. Amazing work by @lvchosen1 with @silvirouskin, @Armstrong_dfci, and many more! cell.com/cell/fulltext/…

Join us Aug 3–6 in Porto for the #FASEB Biological Acetylation Conference! great lineup spanning #chromatin #epigenetics #metabolism #cancer and drug development! keynotes by Asifa Akhtar and Shelley Berger! #BAHSRC2026 events.faseb.org/event/biologic…

@ael2b Congrats Agata! So great to see this out finally!

Our new paper is out in Genes & Development! We found that a small domain in PRC2 — the SBD — isn't just structural scaffolding. It's a mechanical switch that powers the whole complex. Remove it, and cancers driven by EZH2 mutations stop growing. 🧵

Jane Ying Wu, who took her own life, was cleared of wrongdoing by the US National Institutes of Health. Her family alleges that her employer destroyed her career. go.nature.com/3OZDs51

@brangwynnelab @BrunetLab @brkthroughprize @HymanLab Huge congratulations!!

Fantastic weekend at the @brkthroughprize celebration, finally celebrating our Breakthrough Prize in Life Sciences with @HymanLab. What an incredible event!

@yu_jindan @jdlicht Congrats!

So glad to become a member of AAP. With my nominator and sponsor @jdlicht

Heading to San Diego for #AACR26! excited to present our latest work on condensates at the Major Symposium on chromatin, epigenetics, and cancer, alongside leaders in the field @TheRobertsLab1 @Armstrong_dfci. Come join the discussion if you’re interested! @PennMedicine

@rushika_perera @genophoria Congrats Rushika!

Honored to recieve the 2026 UCSF Byers Award in Basic Science. Eternally grateful to my mentors, colleagues and friends for your support and to all the past and present Perera Lab members to whom this honor is dedicated to 🙏🏽

@QinYan1 @UTSWMedCenter @kaelin_lab @yalepathology @YaleMed @Yale Congratulations Qin! Well deserved!!

I am really honored for this. This would not be possible without the hard work of my trainees, guidance by mentors including Joan and Ron Conaway @UTSWMedCenter , @kaelin_lab, David Stern, and Jeff Sklar, and support of my colleagues @yalepathology @YaleMed @Yale, and my family.

@PapapetrouMDPhD @ISEHSociety @beth_psaila Congrats Eirini!

So incredibly honored to receive this award by @ISEHSociety! Congratulations to the other awardees @beth_psaila and Ellen Rothenberg.

@bradylabupenn @TheModzLab @ASBMB Congrats Donita and thanks for all you have done!

Grateful to @ASBMB for this extraordinary honor and to the colleagues who nominated me. This recognition means a great deal because it affirms something I believe deeply: talent is universal, but access is not.