Xiaojing Cong
79 posts

Xiaojing Cong
@XiaojingCong
Computational biophysicist/chemist in #GPCR #DrugDesign and #olfaction @GranierMouillac Lab
Montpellier, France Katılım Aralık 2010
117 Takip Edilen100 Takipçiler

Feeling proud and inspired to be in one of the world's top research institutions, @CNRS!

Jacques Maddaluno@jmaddalu
Journée des entrants du @CNRS aujourd’hui au Beffroi de Montrouge. Bienvenue aux jeunes collègues qui reprennent le flambeau et poursuivent la course des savoirs !
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Big day for OB/GYN! Huge congratulations to @JGMeyerowitz et al. on the first active state structure of oxytocin receptor!
nature.com/articles/s4159…

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Our article “How does a small molecule bind at a cryptic binding site?” has been published in PLOS Computational Biology. doi.org/10.1371/journa…

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An editorial in our March issue discusses how advances in cryo-EM and computational tools have provided new insights into the basis of GPCR–effector interactions: nature.com/articles/s4158…
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#ASAP Machine learning to pair odorants with receptors by chemical similarity & protein sequence. This study by @XiaojingCong, Jérôme Golebiowski & team @Univ_CotedAzur provides the largest database to date & a knowledge-driven solution to data scarcity: go.acs.org/sv

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Just out:
our work on predicting protein-ligand pairs in #olfaction with #machinelearning proteichemometrics,
+ the largest #database of #odorant-#odorrecepetor pairs !
@JodyPacalon
pubs.acs.org/doi/10.1021/ac…
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Registration is open for the @cecamEvents workshop “20 years of Metadynamics”.
September 5-8 2022, Lausanne (CH). Organized by @GroupParrinello, Alessandro Laio,
@BussiGio, @gervasiolab, @evi_gkeka, and myself #compchem #cecam #compBio More info here:
cecam.org/workshop-detai…
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Excited to share our study on the relaxin receptor RXFP1:
biorxiv.org/content/10.110…
Congrats @SarahErlandson for the fascinating structures and insights!

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@GranierMouillac lab delighted to host the brillant PhD students of @ONCORNET1 in the Institute of Functional Genomics Montpellier. Having a great dinner time after the training today!
@OmoladeOtun

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Feeling inspired and motivated at the 5th @ErnestNetwork #SignalTransduction meeting. Great to meet the colleagues in person !!


Bari, Apulia 🇮🇹 English
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Interesting article "Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state" (via #pubmedontap) ncbi.nlm.nih.gov/pubmed/34521824
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We are happy to welcome Antonio MONARI @AntonioMonari in our team @ItodysC. Antonio is hired by @ITODYS_lab @Univ_Paris as full prof in theoretical chemistry #compchem. A warm welcome Antonio!!

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Congrats!!
Dr Lauren T May@laurentmay
Check out our latest publication that provides a mechanistic understanding of A1 receptor-mediated analgesia and moves us step closer to towards the development of new non-opioid treatment options for neuropathic pain. @Nature @MIPS_Australia 👉rdcu.be/cxpot
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#Communiqué 🗞️ | Des scientifiques ont identifié les rouages moléculaires à l’origine des voies de signalisation impliquées dans la réduction de la douleur. Ces résultats ouvrent la voie au développement d’#opioïdes dénués d’effets secondaires. 💊
➡️ cnrs.fr/fr/vers-le-dev…

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Xiaojing Cong retweetledi

Les #opioïdes ont révolutionné le traitement de la #douleur, mais ils sont aussi associés à une "épidémie" d'overdoses. Une étude ouvre de nouvelles pistes pour parvenir à terme au développement d’opioïdes dénués d’effets secondaires.
➡️bit.ly/2WW4WNI

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Online Now: Molecular insights into the biased signaling mechanism of the μ-opioid receptor dlvr.it/S6Dk9h
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