

Paul Gordon
7.4K posts





At one point there were only ~1280 humans left on the planet. Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition science.org/doi/10.1126/sc…




My real estate agent's BROKER just called me at 9pm on a Friday to tell me that the seller doesn't want to sell a house to me because I am BLACK. This is after the inspection, contract agreement, down payment. Baby, I'm either buying your house or buying YOUR BLOCK. CHOOSE ONE.

Ukrainian soldier who returned home today after surviving 2 years in a Russian concentration camp.

Thrilled to share our latest discovery on a spliceosomal snRNA gene causing neurodevelopmental disorders: medrxiv.org/content/10.110… Thank you to everyone who contributed; it’s been a phenomenal effort to collaborate with clinicians and researchers for what would help many families!



The choice of whether to use Seurat or Scanpy for single-cell RNA-seq analysis typically comes down to a preference of R vs. Python. But do they produce the same results? In biorxiv.org/content/10.110… w/ @Josephmrich et al. we take a close look. The results are 👀 1/🧵








My first method work in a new field, we developed an assembly based annotation tool for HLA/KIR genes. Enjoyed working with Heng @lh3lh3 and Li @mourisl ! biorxiv.org/content/10.110…

Just shared at @KeystoneSymp a new @ArcInstitute discovery of the bridge RNA recombinase mechanism: a new class of natural RNA-guided systems that retains the key property of programmability from RNAi and CRISPR while enabling large-scale genome design beyond RNA and DNA cuts