yinxiu zhan retweetledi
The first preprint of our PERICODE consortium: MPRA-trained deep learning provides insight into the regulatory logic of promoters and transcription factors. biorxiv.org/cgi/content/sh…
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yinxiu zhan
27 posts
yinxiu zhan
@YinxiuZhan
Data data data
PhD @FMI now Head @IEO Katılım Temmuz 2017
61 Takip Edilen64 Takipçiler
yinxiu zhan retweetledi
I am happy to share our new work on H3K9me3 in early embryos:
embopress.org/doi/full/10.10…
-H3K9me3 is inherited from the oocyte to the embryo (F1), like H3K27me3.
-HP1a binds independently of H3K9me2/3 in early embryos.
-The formation of HP1a foci is dependent on H3K9me2/3.
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Finally out, great collaboration with @Iovino_Lab. Using imaging, cut&tag and modelling, we showed that H3K9me3 is dispensable for HP1a recuitment during early development in drosophila!
The EMBO Journal@embojournal
Inheritance of H3K9 methylation regulates genome architecture in Drosophila early embryos embopress.org/doi/full/10.10…
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yinxiu zhan retweetledi
In this episode we talked to @LucaGiorgetti from the @FMIscience to hear about his work on long-range transcriptional control by 3D chromosome structure. #chromatin #podcast #epigenetics
Listen here: #luca-giorgetti" target="_blank" rel="nofollow noopener">activemotif.com/podcasts#luca-…
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yinxiu zhan retweetledi
New preprint from our lab: E-E-P massively parallel reporter assay to understand how signals from *two* enhancers are integrated by promoters: doi.org/10.1101/2023.0…
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yinxiu zhan retweetledi
A short Tweetorial on LAMMPS.
LAMMPS (@SandiaLabs) is a v powerful engine to perform molecular dynamics simulations. Albeit popular, there are still some people who struggle to pick it up due to a relatively steep learning curve. I hope this will help you getting started.. (1/n)
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Checkout our last paper! CTCF and cohesin control proximity and looping dynamics! Awesome collaborations with @MachPia @PavelKos7 at @LucaGiorgetti Lab
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Congrats and well deserved! I have been very lucky to have had you as mentor (within and outside science!) and friend! Good job @FMIscience
FMI science@FMIscience
Congratulations to @LucaGiorgetti for his promotion to FMI Senior Group Leader with tenure. With his team, Luca made fundamental discoveries on how enhancers regulate genes over large genomic distances; we are thrilled he will continue his highly innovative research at the FMI.
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yinxiu zhan retweetledi
Very happy to present our last interdisciplinary work on heterochromatin formation, HP1 & Liquid-liquid phase separation. Great work by Maxime👏. Fantastic collaboration with the Karpen lab ! biorxiv.org/content/10.110…
Below for more description 👇
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Congrats Franka and all the people involved!
Franka Voigt@FrankaVoigt
Proud to present our work visualising individual XBP1 mRNA molecules together with the ER stress sensor IRE1 in live cells that has just come out in @eLife. Great collaboration with @AragonAmonarriz. Thanks to all co-authors! elifesciences.org/articles/75580
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yinxiu zhan retweetledi
(1/6) our preprint biorxiv.org/content/10.110… is now out in @ScienceMagazine science.org/doi/10.1126/sc…
Using super-res live-imaging we show that CTCF/cohesin loops are dynamic (~10-30 min median lifetime), rare (~3-6.5% looped fraction), and we fully parameterize a TAD.
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yinxiu zhan retweetledi
What happens to gene regulation when an almost entire TAD is inverted? Check out our work below 👇 @heard_lab @LucaGiorgetti @YinxiuZhan @ElphegeNoraLab @Joke_van_Bemmel @maudborensztein a great team effort as usual :) thank you all 🙏
bioRxiv@biorxivpreprint
Inversion of a topological domain leads to restricted changes in its gene expression and affects inter-domain communication biorxiv.org/cgi/content/sh… #bioRxiv
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yinxiu zhan retweetledi
1/5 I'm very proud to share our new story about the reconstruction quality of 3D chromosome conformation. Thanks to wonderful collaboration: @agalitzina, Sergey Ulianov, Mikhail Gelfand, Sergey Razin, and Alexander Chertovich (mspslab.com). doi.org/10.1371/journa…
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yinxiu zhan retweetledi
Debutta a Milano la scuola per gli imprenditori deep tech startupbusiness.it/debutta-a-mila… @Startupbusiness
Italiano
yinxiu zhan retweetledi
Delighted to share my lab’s @jdavieslab first big paper in @Nature!
We’ve developed a new 3C technique called Micro Capture-C that can generate base pair resolution 3C data nature.com/articles/s4158…
GIF
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yinxiu zhan retweetledi
A paper published in Nature presents a deep-learning algorithm for classification of cancers of unknown primary origin. go.nature.com/3f2tt8W
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yinxiu zhan retweetledi
Come join the fantastic @JensenLab_UCPH in Copenhagen! An amazing group of scientists and a great supervisor!
Kim Jensen@kim_bak_jensen
Interested in regeneration and stem cell biology? Join our team @JensenLab_UCPH for a fully funded postdoc position at @UCPH_BRIC and @UCPH_DanStem. #postdocjobs. candidate.hr-manager.net/ApplicationIni…
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yinxiu zhan retweetledi
Finally out in a peer-reviewed journal @GenomeBiology! PhD project of our first student @GenoletOriana - great work, we are really missing you in the lab! Great collaboration with @boettcher_lab and important contributions from @AnnaAMonaco! genomebiology.biomedcentral.com/articles/10.11…
Edda Schulz@EddaGSchulz
Our first #CRISPR screening paper is out! We identify X-chromosomal genes that drive sex differences in embryonic stem cells. Congratulations to @GenoletOriana and everyone else who contributed @AnnaAMonaco @boettcher_lab! For Tweetorial see thread below. biorxiv.org/content/10.110…
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