jdavieslab

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jdavieslab

jdavieslab

@jdavieslab

Davies lab @MRC_WIMM @UniofOxford

Katılım Eylül 2020
224 Takip Edilen346 Takipçiler
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James Davies
James Davies@jojdavies·
Our latest paper has just been published in Cell! doi.org/10.1016/j.cell… We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
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Nucleome Therapeutics
Nucleome Therapeutics@NucleomeTx·
Delighted that Nucleome is showcased as one of the 50 companies in @PwC_UK’s 'Life Sciences Future 50' report, illustrating the world-class science and innovation being led by the UK’s life sciences sector. Read the report here: bit.ly/3Fnw379
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James Davies
James Davies@jojdavies·
We are looking for an RA to join the lab to work on a fantastic genomics project! jobs.ac.uk/job/DCH089/res… Closing date next week! Please RT - thank you!
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deWitLab
deWitLab@deWitLab·
Very exited to share that our work showing the importance of SOX2 pioneer activity for gene activation has now been published in @embojournal. Excellent work from @michelamaresca and @TeunvandenBrand. And a nice collaboration with @jojdavies (+lab). embopress.org/doi/full/10.15…
deWitLab@deWitLab

We are excited to share a new pre-print in which we use acute depletion of the pioneer factor SOX2 to study its role in regulating transcription. This project was spearheaded by @michelamaresca and @TeunvandenBrand in my group. A 🧵below biorxiv.org/content/10.110…

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paresh vyas
paresh vyas@pvyas_oxford·
Delighted to share our new approach for high fidelity sc genotyping combined with scATAC - called GTAC! Do check it out! We love it. Great collaboration with the Hughes and Davies labs also in the WIMM. Credit to Sven, Asger, Angus and all co-authors. cell.com/cell-stem-cell…
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Knight Genetics
Knight Genetics@KnightGenetics·
We are excited to share our recent work mapping the host response to sepsis at single-cell resolution. The study, led by @andrewjkwok and published in @NatImmunol, identifies a subset of immature neutrophils which is increased in severe sepsis. Big thanks to everyone involved!
Nature Immunology@NatImmunol

Julian Knight and colleagues find that altered granulopoiesis and increases in immature immunosuppressive neutrophil subsets are associated with poor outcomes in some patients with sepsis. Read it here: rdcu.be/daDeU nature.com/articles/s4159…

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Adam Mead
Adam Mead@AdamMead_Oxford·
The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia ascopubs.org/doi/10.1200/JC… TAL1 non coding mutations predict induction failure and poor outcome in T-ALL. Terrific work from @Marcrmansour and colleagues.
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James Davies
James Davies@jojdavies·
In 2016 I looked after a girl who died during a transplant for HbE beta-thalassaemia. I am overwhelmingly pleased that we have been able to correct HbE with near 100% efficiency using base editors. nature.com/articles/s4146… Brilliant work from Mohsin Badat @Montytrench @jdavieslab
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Joseph Hamley
Joseph Hamley@josephhamley98·
Really pleased to see our @NatureProtocols paper out this week. We have put together a comprehensive guide to generating base resolution 3C data! @hangpengli578 @jojdavies @jdavieslab
James Davies@jojdavies

Really pleased to share the detailed protocol for Micro Capture-C in nature protocols. It is capable of generating 3C data down to base pair resolution. @jdavieslab @hangpengli578 @josephhamley98 @MRC_MHU @MRC_WIMM rdcu.be/c8GWN

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Mark Dawson
Mark Dawson@MAF_Dawson·
Cofactor requirements for transcription factors! A labour of love for @charles_bell92 - so very proud of him and all in @TheDawsonLab involved. A body of work that is not only amazing in scale but also tackles an important and tough question in our field - Enjoy!
Charlie Bell@charles_bell92

Proud to present my latest work with @MAF_Dawson investigating how transcription factors and core promoters influence the mechanisms of transcription biorxiv.org/content/10.110… Results described below 👇🧵

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Sven Turkalj, PhD
Sven Turkalj, PhD@SvenTurkalj·
Delighted and honoured to receive the ASH Abstracts Achievement Award for our oral presentation at this year's @ASH_hematology meeting! Very grateful for the mentorship @pvyas_oxford and to my fantastic colleagues at the @MRC_WIMM. This was a true team effort! #ASH22
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Keşfet

@hangpengli578 @MRC_MHU @MRC_WIMM @UniofOxford @CellCellPress @PwC_UK @embojournal @michelamaresca