Youcef Mehellou

@BrittonLab @DrLCsquare @ScienceMagazine @Merck @asymtmm Impressive work. Congratulations.

New paper alert!!! 🚨🚨🚨 We report "A unified platform for nucleoside analog synthesis" in @ScienceMagazine Congratulations to Matthew, Ethan, the rest of the team and our @Merck collaborators @DrLCsquare and @asymtmm for this monumental publication! science.org/doi/10.1126/sc…

Fully funded PhD studentship available in my lab in Cardiff University. - Most suitable for candidates with interest in medicinal chemistry and drug discovery. - Closing date: 21/03/2025. - Contact me for enquiries. @PharmacyCU findaphd.com/phds/project/a…

Happy to share that our paper looking into the role of OSR1 kinase in promoting breast cancer oncogenic potential is now out. @PharmacyCU pubs.acs.org/doi/10.1021/ac…

We are deeply saddened to share that our friend and colleague Professor Amos B. Smith III has passed away. Amos joined Penn in 1973 and was a mainstay in our organic chemistry division. He recently celebrated 50 years of service to @PennSAS @Penn.

Great news - Accession receive MHRA approval for first in human clinical trial of TROCEPT-01 across six UK sites in a range of recalcitrant tumour types. Fantastic to see an agent initially developed @cardiffuni in my @virustinkerer make it to clinic. mailchi.mp/9425dbf8fce8/a…

Very sad news of the passing of @sirfrasersays, a giant of chemistry for four decades. He pioneered (with J-P Sauvage) the chemistry of the mechanical bond (catenanes & rotaxanes) & recognised that their well defined motions could be useful for molecular machinery... 1/3

Post-doctoral fellow position for 3 years on the structural biology of signaling complexes downstream of LRRK2 kinase, in the lab of Amir Khan, Dublin, Ireland. This is a collaborative position with Dario Alessi at the MRC PPU, Dundee, Scotland ppu.mrc.ac.uk/careers/recrui…

New opportunity for a Lecturer (Assistant Professor) in Chemical Biology at the University of Bath! bath.ac.uk/jobs/Vacancy.a…

📢In this year's GPhC registration exam, our graduates performed top in the UK with a pass rate at first attempt of 93%. We're very proud of their achievements! 🎉

**MEETING ALERT** @BiochemSoc @ASAP_Research 20th Anniversary meeting on #PINK1 mutations in #Parkinsons. Fantastic lineup of speakers; industry and clinical talks and many early-career speaker slots. To register and learn more click: shorturl.at/LnXZM

@FiedlerLab Looks really interesting. Well done.

During our investigation of protein pyrophosphorylation, we identified a novel post-translational modification (PTM), which we have termed 'Protein Oligophosphorylation'. biorxiv.org/content/10.110…

📢 Two new preprints alert! LRRK2-a kinase associated with #Parkinson’s and #crohn's #IBD. But where is it expressed and active? Not in Paneth cells, important for Crohn’s, but IL-4 induced in B cells, and other immune cells- see tinyurl.com/mwz4py7u tinyurl.com/mpvfhw44

“My time at the MRC PPU was truly formative for my scientific career." @Gerta_Hoxhaj, MRC PPU Alumni & winner of the prestigious 2024 @Vilcek Prize for Creative Promise in Biomedical Science Full interview on our website: ppu.mrc.ac.uk/about-us/alumn…

The landscape of small-molecule prodrugs bit.ly/43I3X1U This new review analyses approved prodrugs to reveal trends in their development, highlighting design rationales, indications, mechanisms of API release, chemistry of promoieties and the market impact of prodrugs

@sybanerjee @cardiffuni @mrcppu @UoDMedicine Thank you Sourav for visiting us and sharing with us your work on protein kinases. I look forward to seeing how your projects progress in the future.

Had a great day engaging with students, post docs, and group leaders at College of Pharmacy @cardiffuni. Thank you very much @YoucefMehellou for inviting and hosting me for a seminar. Truly enjoyed reminiscing the @mrcppu days. Cardiff is beautiful. @UoDMedicine

Edrych ymlaen at brynhawn o ymgysylltu ag ysgolion Grangetown a @YoucefMehellou fel rhan o wythnos Gyrfaoedd a Modelau Rôl! Looking forward to an afternoon of engagement with the schools of Grangetown and @YoucefMehellou as part of Careers and Role Models week! #STEM

@ElvisiDusha 💔💔💔

May GOD bless the family of the young boy who lost his life today during a U16 basketball semi final match in albania. Heart goes out to the families & the young kids who witnessed this tragic incident. 💔😢

What an away win for Cardiff City U14 basketball team today! Great move from Teilo 🔥 @BrgVibe

A few years back I started a journey to learn more about biopharma and drug discovery. Here is a list of the books I have found helpful (loosely grouped by topic) with the outstanding books highlighted by (+++). Feel free to add your own recommendations, I'll keep adding mine.

Out Now! Our new preprint of mechanism of #PINK1 activation at TOM complex. Led by Wale @waleraimi & Hina @mrcppu Fantastic collaboration with @ruferbus Sebastian Mathea @ASAP_Research Karim Labib @naranson @TDDeego. #OpenScience click here surl.li/oqvpt