Yugang GUO

IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases go.nature.com/3vh5Bdv

@Tang_Lab_EPFL @LeiKewen @ArmandKurum So proud to grow with the fast growing team!

Nothing more satisfying than seeing your trainees grow! An amazing lab retreat with really cool science, great presentations, and fun bowling night! Congrats to the winners @LeiKewen @ArmandKurum, Bing, Rongrong!

Interested in working on the next generation of cancer immunotherapies? The Tang Lab at the Swiss Federal Institute of Technology in Lausanne is looking for a postdoctoral researcher with a strong background in immunology, metabolism, and mouse studies. See below for more info ⬇️

Thanks Pr. Richard Klemke for highlighting our work in Faculty Opinions. "Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity"- recommended in @FacultyOpinions facultyopinions.com/prime/740163541

Thank ACIR for nice report for our work. acir.org/weekly-digests…

Our lab's new paper (rdcu.be/clkR2) on metabolic reprogramming of exhausted CD8+ T cells is now out at @natureimmunology, highlighted as a cover story! (1/7)

#cancer Tang and colleagues show that a half-life-extended IL-10–Fc fusion protein enhances proliferation and effector function of terminally exhausted T cells via metabolic reprogramming which can eradicate established solid tumors in mice.rdcu.be/cld9s