Yunyan Sun
169 posts

Yunyan Sun
@YunyanSun
Assistant Professor @ECNUer; Working at the interface of bio/organic/polymer. Interested in molecular design and its applications in bio/organic materials.
Katılım Eylül 2018
383 Takip Edilen330 Takipçiler

I'm thrilled to share that I will be starting my independent career @IUBChemistry in July! The Wentz lab will interface synthetic chemistry with materials science, while providing strategies to access new generations of molecular building blocks and macromolecular materials.

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My group at RWTH DWI Leibniz institute for interactive materials will have 2 PhD postions open. If you are in polymer chemistry, please send me emails at jwang@dwi.rwth-aachen.de. Details here: dwi.jobs.personio.de/job/2017091?la…, dwi.jobs.personio.de/job/2017317?la…
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🚨RADICAL RETHINK: STEREORETENTIVE CROSS COUPLING UNLOCKED🚨 Today in @ChemRxiv (chemrxiv.org/engage/chemrxi…) the first method for stereoretentive radical cross-coupling is disclosed. No fancy ligands or redox needed—just a Ni-diazene twist. 120 years after Gomberg, a new chapter begins.
Quick summary:
Since Gomberg discovered free radicals over 120 years ago and Kochi pioneered radical cross-coupling in the 1970s, this field has surged with interest for linking C(sp3) fragments. Unlike traditional polar methods (e.g., Suzuki), radical cross-coupling excels with saturated systems, offering mild conditions and chemoselectivity to build complex molecules from common fragments. Until now, enantiospecific radical cross-coupling was deemed impossible due to rapid racemization, but today that changes with readily available sulfonylhydrazides and a simple Ni-catalyst. This stereoretentive approach, enabled by a unique Ni-diazene transition state and driven by loss of N2, skips chiral ligands and redox steps, opening new possibilities for synthesis.

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Excited to share our work in @nature on H-bonded organic frameworks as ultrasound-programmable drug delivery system! Congratulations to @wangqenliang92 @advancedlnp @KingRaychard @KaiWTang and all our collaborators! @UTBiomedical @UTAustin @NSF @NIGMS nature.com/articles/s4158…
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I'm very excited to share that I will start my independent career as an Assistant Professor @BaylorCBC starting August 2025! My team will integrate computational chemistry, cheminformatics, and machine learning to innovate in catalysis and materials!
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Thrilled to share my postdoc work is online in @J_A_C_S . We used a rheo-fluorescence set up to directly see and quantify bond breakage events when associative polymer undergoes large shear deformation. Thanks to my advisor and all coauthors! pubs.acs.org/doi/10.1021/ja…
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Congrats @Hai_Qian ! Nice approach to tune the force transmission!
Hai Qian@Hai_Qian
Thrilled to share our 1st paper in @angew_chem! We introduce a cyclic pulling geometry to tailor force transmission within a mechanophore, enabling modulation of reactivity & the construction of hierarchical mechanophore systems. bit.ly/3UPWtqe #polymer #mechanochemistry
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The Restoring Force Triangle: A Mnemonic Device for Polymer Mechanochemistry | Journal of the American Chemical Society @Mechanophore @UofIllinois @BeckmanIllinois #Restoring #Force #Triangle #Polymer #Mechanochemistry pubs.acs.org/doi/10.1021/ja…
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Check out my last piece of work in my PhD with @Mechanophore! We developed a “cartoon picture” ( a triangle!) to make sense of mechanochemistry under tension. Special thanks to all the reviewers who helped to greatly improved the manuscript! doi.org/10.1021/jacs.4….
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@Mechanophore @CciMonet Beyond the fundamental insights in the paper, here is one figure I think can be helpful practically (suggested by one kind reviewer!) It tells us the “privileged handles” we should use to incorporate mechanophores.

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Many thanks to Jeff who has contributed a ton to this paper! Please make sure to check out the interactive python tool developed by @Mechanophore in the SI!!! Also thank Fangbai who helped to conduct a few simulations. Also thanks the support from @CciMonet
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@YunyanSun Totally a team effort @YunyanSun Very delighted to be part of this work
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BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

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For me it is always fun to work on some fluorescent materials and it is amazing to see that colorful emission can be achieved by mechanophores. Congratulations to the MONET team!
Yunyan Sun@YunyanSun
Please check out our work @J_A_C_S on Multicolor and White Emission from Mechanically Caged AIEgens. pubs.acs.org/doi/10.1021/ja… I am glad it is also selected as the ACS Editor’s Choice! This work was done with a phenomenal undergrad @CHEM_Kecheng who will apply for grad school soon
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Please check out our work @J_A_C_S on Multicolor and White Emission from Mechanically Caged AIEgens. pubs.acs.org/doi/10.1021/ja… I am glad it is also selected as the ACS Editor’s Choice! This work was done with a phenomenal undergrad @CHEM_Kecheng who will apply for grad school soon
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