Yuval Malka

Introducing 'RNA Dicing': Discover how JAK1 mRNA's translation potential is just the tip of the iceberg. Our findings redefine nonsense mutations and advance personalized medicine, unveiling the intricate modularity of genetics. @liamfaller biorxiv.org/content/10.110…

My dad, who is a moderate Muslim, finally expressed his concern and asked me, 'Why are you supporting this genocide?' He mentioned that he's stopped looking at his phone because he can no longer bear to watch videos of Palestinian children being bombed by Israel. I replied, 'I empathize with the suffering, and it's not easy for me either.' Then I showed him a photo, and we both agreed on the gravity of the situation in Palestine. I then informed him that the photo was actually of a Yemeni child pulled from the rubble resulting from a Saudi bombing in Yemen. I pointed out that Israel has allegedly killed 7,000 Palestinians, while the Saudis have killed at least 150,000 Yemeni Muslims. Some estimates suggest upto 300,000. How can we call the current conflict a 'genocide' when what the Saudis did is hardly even discussed by Muslims? Don’t get me started on 200,000 Muslims killed by Bashar Al Asad in Syria. He responded that if that's the case, he also disagrees with what the Saudis did. I replied, 'How convenient. Nearly half a MILLION fellow Muslims have been killed by other Muslims, and you didn't even know about it. Yet when Israel retaliates against a terrorist organization that has killed, raped, and maimed 1,500 of its citizens, the whole Muslim world reacts?' It seems to have less to do with preserving Muslim lives and more to do with a religious fantasy of hostility toward Jews.

From the debate in the Lords yesterday on Israel & Gaza. Guglielmo Verdirame: professor of international law at the King’s College London. “There has been a lot of talk about proportionality in the law on self-defence. I refer to the words that the noble Lord, Lord Pannick, 1/

This hate is not only towards the Israelis but also towards groups that are perceived as different from them. These individuals would not engage in such actions in Western societies without the collective sentiment. Supporting them equates to supporting this, clear and simple.

@SorkinRaya Congrats!!

So excited to be awarded the #ERCStG for our project ReMembrane!🤩 We will explore membrane remodeling by tetraspanin proteins using mechanical-single-molecule tools, in the context of migrasome formation, viral fusion and fertilization! NOW RECRUITING STUDENTS AND POSTDOCS!

@mashlosenok @AgamiLab @alkan_ferhat @liamfaller Hi! this analysis calculates the expression of RNA relative to the predicted cleavage point in each transcript. So if you would imagine that the mRNA is cleaved, the upstream fragment to the cleavage point will be capped while the downstream will be uncapped.

@YuvalMalka17 @AgamiLab @alkan_ferhat @liamfaller .. And same applies for the CAP IP data. or am I reading it wrong? 🥲

How well do we understand the complexity of the transcriptome? in our new study (@AgamiLab, @alkan_ferhat, @liamfaller, and more), we uncover an unexpected function of cleavage and polyadenylation, which generates thousands of novel uncapped mRNA isoforms! authors.elsevier.com/sd/article/S10…

Thank you, @lisa_heinke, for an excellent Research Highlight in @NatRevMCB on our recent paper in @MolecularCell!

Did you think gene expression, transcriptome & translatome can't get any more complicated? In this issue of @MolecularCell , we (@YuvalMalka17, @liamfaller, @AgamiLab) show that thousands of uncapped RNAs with PolyAtail exists & gets translated!!! cell.com/molecular-cell…