Ferhat Alkan

Soon leaving here completely to set sail in bluer skies 😉 I also promised myself to be more active there. I hope you do the same and save yourself from this rotten platform.

Introducing 'RNA Dicing': Discover how JAK1 mRNA's translation potential is just the tip of the iceberg. Our findings redefine nonsense mutations and advance personalized medicine, unveiling the intricate modularity of genetics. @liamfaller biorxiv.org/content/10.110…

Amazing work, everyone! Visualization of translation reorganization upon persistent ribosome collision stress in mammalian cells. sciencedirect.com/science/articl…

As a founder you live for these moments 🥲 Anyone looking for Webflow X Shopify integration, give Shopyflow a try. You will love it.

Hello Folks! Let's help my dear friend Martin and his Give a Bike Foundation to recover from the tragic Keilewerf fire gofund.me/dae49e94

Happy to announce that I will be a speaker at #NWOLife2023 🤓 My 10 mins talk on #RibosomeHeterogeneity will be a great fit to the conference theme "Diversity of Life" 🎉 Hope to see some of you there! nwolife.nl @NWONieuws

Sign-up for this amazing conference to see how awesome and diverse ribosomes can be❕It has the most exciting line-up 💫🔥 forms.royalsociety.org/s/VZ5V3W/

“It’s time to demand our seat at the table”, says postdoctoral fellow @TheJoanaSilva. @EULIFE_news interviewed her for International Day of Women and Girls in Science. “STEM is for everyone and your thoughts and ideas matter.” Read more ➡️ bit.ly/3RQw88M #WomeninSTEM

@ewjwallace @BinfoTrends @premal_shah @AMeynert @AudreyGasch academic.oup.com/nar/article/50…

@ewjwallace @BinfoTrends @premal_shah @AMeynert @AudreyGasch I’d check this out!! CRISPRroots: on- and off-target assessment of RNA-seq data in CRISPR–Cas9 edited cells

Genetics professor’s research reveals that the role ribosomes play in what cells become and how they behave is far more important than previously known. @mbarnalab #Genetics #ScienceTwitter #StanfordMedMag stan.md/3R5RFtH

As the new year begins I’d like to share some news. From May I will join @UMCU_CMM as group leader. I will focus on exploring transcription factor action to leverage discovery of new targetable routes/biomarkers in cancer, & hopefully down the line impact patient-care. #newPI

I am thrilled to share our new paper published in #CancerResearch about how N-myc drives selective translation of transcripts that promote protein homeostasis in medulloblastoma. It was a privilege to collaborate with Bill Weiss & Ozlem Aksoy. aacrjournals.org/cancerres/arti…

We are delighted to announce our next RNA Society Member Spotlight! Dr. Maria Barna, an Associate Professor of Genetics at Stanford University, studies how ribosomes shape organismal changes during development: rnasociety.org/professor-mari…

What does a human collided disome look like? In collaboration with the Inada lab, we show that mammalian disomes form a distinct structural interface, in which uS10 K63-linked polyubiquitination is critical for ribosome dissociation. ⬇️⬇️⬇️

How well do we understand the complexity of the transcriptome? in our new study (@AgamiLab, @alkan_ferhat, @liamfaller, and more), we uncover an unexpected function of cleavage and polyadenylation, which generates thousands of novel uncapped mRNA isoforms! authors.elsevier.com/sd/article/S10…

Did you think gene expression, transcriptome & translatome can't get any more complicated? In this issue of @MolecularCell , we (@YuvalMalka17, @liamfaller, @AgamiLab) show that thousands of uncapped RNAs with PolyAtail exists & gets translated!!! cell.com/molecular-cell…

OMG! We have a Nobel winner, who is openly lesbian, loves to play street basketball, and used to be in a band with awesome Tom Morello. @CarolynBertozzi is a legend in so many ways !!!

Excited to share our new publication on creating a roadmap for ribosome heterogeneity during stem cell differentiation and its impact on organismal development. A single ribosomal protein can control development of one of the three germ layers! rdcu.be/cVTvx

@AnoekFriskes @LisaKoob6 @MedemaRene @WilbertZ Great work everyone!!! I'm also superhappy to see that CRISPRoff scores could indeed help assessing those potential off-target sites 😉

Can double-stand break (CRISPR/Cas9) toxicity vary between different chromatin environments? We studied it. Excited to share these insights with you. Great collaboration with @LisaKoob6, MedemaLab @MedemaRene and @WilbertZ lab. doi.org/10.1093/nar/gk…