Charles 🟦

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Charles 🟦

Charles 🟦

@_CharlesSo

BKK/CNX Katılım Haziran 2023
2.3K Takip Edilen278 Takipçiler
Matt Hunt
Matt Hunt@WritingByMatt·
@bangkokaussie It removes the incentive to monetize political content outside of your account’s locale
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Charles 🟦
Charles 🟦@_CharlesSo·
@KHAMCHANH I also think the aspect of not going to friends house results in interaction outside of the home. In which this means places to eat, drink, party, etc.
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Charles 🟦
Charles 🟦@_CharlesSo·
I often feel like there is this vibe of new money among the middle class in the 30's range where they prolong typical behavior that is reserved for 20 year olds due to the aspect people come to the country to party. It's like other tourist places, the vibe becomes a bit more on supporting that and normalizing it.
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KHAMCHANH
KHAMCHANH@KHAMCHANH·
I think a reason for low birth rates in Asian countries is the rapid and intense urbanization + high level of internet connectivity. Many people blame cost of living, but let’s be honest, very few Asians don’t want to have children before the age of 30 regardless of costs.
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Charles 🟦
Charles 🟦@_CharlesSo·
@nikitabier What if your home country is US or whatever, but you live half the year in another country. Is this IP or settings based?
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Nikita Bier
Nikita Bier@nikitabier·
Starting Thursday, we'll be updating our revenue sharing incentives to better reward the content we want on X: We will be giving more weight to impressions from your home region—to encourage content that resonates with people in your country, in neighboring countries and people who speak your language. While we appreciate everyone's opinion on American politics, we hope this will disincentivize gaming the attention of US or Japanese accounts and instead, drive diverse conversations on the platform. We invite creators to start building an audience locally. X will be a much richer community when there's relevant posts for people in all parts of the world.
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Brunella
Brunella@brunellaism·
@drumm_colin but the I feels hysterical... the we is bureaucratic and impersonal
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Brunella
Brunella@brunellaism·
i'm using the royal we in my thesis
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Bryan Johnson
Bryan Johnson@bryan_johnson·
Two doses of magic mushrooms degraded my sperm count from the 99.6th percentile to the 77.7th. This may be a first-in-human observation. Context: we ran the most quantified magic mushroom (psilocybin) experiment ever conducted. We were asking if psilocybin is a longevity therapy. After seeing the data, we think it is (see reply post for the experiment summary). Also, like most things biology: the results are complicated. My data suggests that the magic mushrooms (psilocybin) negatively impacted my fertility markers. Before the first psilocybin dose my motile sperm count was at 99.6th percentile for men under 25 years of age, it dropped to 77.7% and partially recovered to 89.3% following the first dose, and second doses, compared to the same age cohort (numbers compare similarly to my age cohort as well). 3 days following my second dose (first dose 25 mg, second dose 28 mg) . Motility: dropped 51% . Total count: almost unchanged, dropped by 2% . Total motile count: dropped 52% . Normal morphology: dropped by 50% 20 days post 2nd dose, the pattern continued, with typical latent effects on total sperm counts Motility: recovered back to -2% of pre-psilocybin baseline: . Total count: dropped by 38%, latent effect. . Total motile count: remained inhibited at -39% of pre-psilocybin baseline, (despite motility normalizing, due to the total count drop) . Morphology normalized to -10% of baseline levels. Reduction in free testosterone might have contributed to the effect. While total serum testosterone increased by 30% 3 days following the 2nd dose (neither FSH or LH were meaningfully affected either), and continued to be at 11% above baseline, SHBG increased by 37%, SHBG binds testosterone and reduces its bioavailability and activity. My free testosterone (direct) showed 24% and 23% drops at 3 and 20 days post 2nd dose. In light of the neuroplastic, well-being, brain reset, and systemic metabolic and anti-inflammatory benefits, the trade-off is probably worth it. Especially considering that the magnitude of inhibition has no meaningful effect on actual fertility (total motile counts above 50 million are still on the safe side). This is a first-in-human observation, to our knowledge there is no published human clinical study demonstrating that psilocybin diminishes male fertility markers. General mechanistic evidence exists for recreational and psychoactive drugs possibly inhibiting fertility markers due to their effects on the hypothalamus-pituitary-adrenal axis and general hormonal reset.  Yet no direct evidence for psilocybin or other similar psychedelics inhibiting fertility markers exist. A potential mechanism for the immediate inhibition of motility could involve direct serotonergic signaling in sperm. Human sperm express multiple serotonin receptors, including 5-HT2A, and one recent study found that a 5-HT2A antagonist reduced sperm motility, suggesting that 5-HT2A may regulate motility. Psilocybin is known to bind 5-HT2A with high affinity.
Bryan Johnson tweet mediaBryan Johnson tweet media
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Charles 🟦
Charles 🟦@_CharlesSo·
Whatever happens with Iran, I just wanna visit there without being kidnapped… Do whatever you need to do Just make it happen
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Charles 🟦 retweetledi
thermo
thermo@DionysianAgent·
the biggest impact of chatgpt was that it enabled women and retards to pretend to be intelligent on the internet
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Charles 🟦
Charles 🟦@_CharlesSo·
If you meet a girl and she has a photo of her holding a wine glass, I think you instantly block them.... they're cosplaying
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NIK
NIK@ns123abc·
🚨FBI: “Day One Ventures @mashadrokova was in Silicon Valley to steal technology…”
NIK tweet media
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Charles 🟦
Charles 🟦@_CharlesSo·
why would they wanna know.... if its not...
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Charles 🟦
Charles 🟦@_CharlesSo·
Idk why you guys are so focused on round numbers... Everyone know 1,204,395.73 is the right amount of money
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Marc Lou
Marc Lou@marclou·
I’m about to swallow $4.53
Marc Lou tweet media
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Russian Market
Russian Market@runews·
OIL PANIC IN ASIA "God knows who told them that petrol prices are going to increase, so everyone has lined up to fill their tanks."
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Charles 🟦
Charles 🟦@_CharlesSo·
@mikadontlouz Isn’t it darker that both men and woman are now sololy focused on attention vs stable relationships and they’ve swapped their values?
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Mika
Mika@mikadontlouz·
There’s a reason Clavicular streams feel so uncomfortable to watch They follow a very specific psychological structure Short breakdown below:
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Charles 🟦
Charles 🟦@_CharlesSo·
The issue with how people are using game theory, it's not about predicting its about creating statical likelihood of different paths forward It's not a binary thing
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kache
kache@yacineMTB·
whats inside
kache tweet media
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Jacob in Cambodia 🇺🇸 🇰🇭
Jacob in Cambodia 🇺🇸 🇰🇭@jacobincambodia·
Dramatic footage from last night's raid on the Golden One building in Phnom Penh's Boeung Keng Kang district. 65 detained, eight Chinese nationals among them, computers and phones seized. The operation targeted an online scam ring using fake profiles to lure foreign investors. The Phnom Penh governor says scam operations will be fully cleaned out by mid-March.
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