Connor Stead

Dynamic time course of muscle proteome adaptation to programmed resistance training in rats journals.physiology.org/doi/abs/10.115…

We quantified mRNA abundance, translation, protein abundance, protein degradation and cell growth across thousands of single cells from a mammalian tissue. The results revealed 𝐜𝐨𝐦𝐩𝐥𝐞𝐱 regulation & 𝐬𝐢𝐦𝐩𝐥𝐞 organizing principles: biorxiv.org/content/10.110… 🧵

Very pleased to see our chapter on Muscle Proteome Dynamics published in The Skeletal Muscle: Plasticity, Degeneration and Epigenetics - A collection of brilliant chapters from leading researchers on muscle biology. link.springer.com/chapter/10.100…

Science is not a zero sum game. The more we collaborate, the more we combine data, the greater the likelihood that together we'll discover new things.

Adaptive time course of the skeletal muscle proteome during programmed resistance training in rats biorxiv.org/content/10.110… #biorxiv_physio

Exercise-Specific Adaptations in Human Skeletal Muscle: Molecular Mechanisms of Making Muscles Fit and Mighty sciencedirect.com/science/articl…

Thank you @kenkhallenbeck for nicely summarizing our @molcellprot article in @ASBMB. Sibling study reveals mechanism for genetic disease asbmb.org/asbmb-today/sc… @LJMUSportSci @LJMU @LJMUImpact @ChildrensNatl @FSHDSociety @MDUK_News @FSHDUKgroup @FSHDEurope @FSHD_Leiden #FSHD

- People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training - Cool new article by @ExercProteomics, @mackinprof & Co. …iencejournals.onlinelibrary.wiley.com/doi/10.1002/pm…

People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training pubmed.ncbi.nlm.nih.gov/37963832/ Obesity and insulin resistance are associated with compromised muscle proteostasis, which may be partially restored by endurance exercise.

Amazing day yesterday at the Healthy Muscle Ageing Conference #hmac2023 Well done @ExercProteomics @jlAreta @pugh_jamie @KelsieOJohnson Amazing speakers @mackinprof @LeighBreen @csbd7 @OllyWitard @CazStaunton @mette_contact So much great info and inspiration for future research

Results for the Poster competition 🏆 🥇Stuart Hesketh 🥈Marie Korzepa 🥉 Hanan Sharkh Huge congratulations to everyone who presented a poster today 🥳 @ARThealthyaging @LJMU @LJMUSportSci @ProrizonTech @BBSRC @BiochemSoc @physoc

News on our recent work on #FSHD here musculardystrophyuk.org/news-blogs-and… Well done @YNishimura87 @_ConnorStead and a big thank you to @MDUK_News @LJMUSportSci and our collaborators Yi-Wen Chen and Adam Bittel @ChildrensNatl

Interested in muscle ageing? Join us at the Healthy Muscle Aging Conference in Liverpool on September 15th Registration is open now and you can be in with a chance to win FREE REGISTRATION Full details: tinyurl.com/3hz6t2ap #HMAC2023

Healthy Muscle Ageing Conference @LJMU ljmu.ac.uk/conferences/He… The first Healthy Muscle Ageing Conference (HMAC), here at Liverpool John Moores University (LJMU).

IN PRESS THP: - RT ⬆️ strength, hypertrophy & physical function VS no exercise - Load, volume, frequency, exercise order impact strength gains - Volume and contraction type impact hypertrophy Nice work team! @mackinprof @MACleod_JC sciencedirect.com/science/articl…

SAVE THE DATE - Healthy Muscle Ageing Conference 15 September 2023 - more details coming soon From one of our pump-priming projects led by @ExercProteomics #TranslationalStudies

Our latest study on the effects of training following a low carbohydrate high-fat diet on skeletal muscle epigenetic regulation is now out in @AJPEndoMetab. (w/@DrAdamSharples @pete_gorski @dcturner93, @JamesyMorton) journals.physiology.org/doi/abs/10.115… Results are not what we expected!🧵 1

Muscle of obese insulin-resistant humans exhibits losses in proteostasis and attenuated proteome dynamics that are improved by exercise training. biorxiv.org/cgi/content/sh… #bioRxiv

We are recruiting participants to study how protein supplements with/without Urolithin A impact muscle health during single-leg immobilization. Please share and contact me (see image) if interested!

Today was the launch of our Liverpool Muscle Healthy Aging study! @ExercProteomics @richjfoster @pugh_jamie @KelsieOJohnson @Richie_Kirwan