Elena Splendiani

Spatial Omics enthusiasts!! Spatial Proteomics is the Method of the Year 2024 🤩🤩🤩 nature.com/nmeth/volumes/…

Strongly absorbing dyes, such as a common food color tartrazine, temporarily render live animal tissues transparent, enabling deep optical imaging of internal structures and activities.science.org/doi/10.1126/sc… #NBThighlight

i am so excited about our open source inexpensive, sub-cellular capture, do-it-yourself Open-ST that transforms tissues into virtual tissue blocks in 3D - IDing pathways & gene programs driving phenotypes. a huge congratz to the team! cell.com/cell/abstract/…

Our #OpenST paper is now online @CellCellPress! authors.elsevier.com/c/1jJckL7PXqR3U Very cool updates ahead🧵⬇️ @L_Marie_Schott @_Elena_93 #GiuseppeMacino @nu_karaiskos @N_Rajewsky

uLIPSTIC is a new method from the @victora_lab for directly observing physical interactions between cells: bit.ly/3Toi0pO Victora: “With uLIPSTIC we can ask how cells work together, how they communicate, and what messages they transfer. That’s where biology resides.”

sciencedirect.com/science/articl… Can we predict response to treatment with circulating biomarkers? We tried to answer this question through a fine literature selection about advanced melanoma patients treated with immunotherapy #Melanoma #Circulating #Biomarkers #Immunotherapy #response

A spatial transcriptomics method that… 🧪is easy to use 🔬has high resolution 🪙is cost-efficient 🌍scales to 3D Just in time for Xmas: Open-ST, a end-to-end, open-source method that checks all boxes, from the @N_Rajewsky lab 📄Preprint: tiny.cc/openst 🧵⬇️

here it is- read about 3D virtual tissue blocks, metastasis-lymph node boundaries and unlocking molecular mechanisms in 3D. biggest congratz to the entire team. Open-ST: High-resolution spatial transcriptomics in 3D | bioRxiv biorxiv.org/content/10.110…