Dr Emily Frost

Ever wondered what signals drive the activation of primordial follicles into the growing pool of follicles? We use scRNAseq to ask this question in the mouse ovary, described in this preprint summarising my two years at @TheCrick 🎉🎉

NEW CNE PAPER! Investigating GABA Neuron–Specific Androgen Receptor Knockout in two Hyperandrogenic Models of PCOS @IreneSucquart @CuriousCoyle @valentinarp979 Melanie Prescott @dr_kellyg Kyoko Potapov @DPBegg @RG_EggLab @KirstyWalters7 @RECampbell_inNZ academic.oup.com/endo/article/1…

Our February issue is online! Read about oocytes from stem cells (@RG_EggLab @_emilyrfrost), Ganoderma lucidum as a next-generation cell factory, precision fermentation for non-alcoholic beer (@s_kampranis) and more: cell.com/issue/S0167-77…

Contraception is a blunt tool. It's high time that we explore its effects on fertility, as well as its interrelationship with biological sex. Tap below to watch @GunesTaylor dismantle how we regulate fertility in the modern world. iai.tv/video/the-cont…

Congrats to @RG_EggLab and collaborators in Vietnam and Brussels for the success of CAPA-IVM. It’s incredible to be witnessing the translation of a career in biomed to outcomes for patients - what a day!! 🤩

Nevertheless, we are in a very exciting time in women’s health research! Here's the link to our article: authors.elsevier.com/c/1he6wc9XEjWF1 Huge thanks to @RG_EggLab for all your efforts @UNSWMedicine. Please reach out and let us know what you think 😊

There’s lots of open questions surrounding IVG. Even if IVG can be achieved, will it ever be safe? Assessment of mutational load, risk to future generations and the testing of eggs without generating a pregnancy are all factors considered in our Outstanding Questions.

One BIGGGGGG question (with a million different answers): How long until we can make human gametes entirely in a dish? Our new opinion article is out in @TrendsinBiotech, where we discuss why we think in vitro gametogenesis (IVG) in women will be incredibly challenging🧵.

@GunesTaylor @TheCrick @BadgeRobin @scientistjessie What a way to start!! Glad the Aussie contingent at the Crick is still bringing the fairy bread goods 🤩🤩

This week we welcomed Brendan Crow to @TheCrick for his PhD - another me, @BadgeRobin & @scientistjessie collaboration 👌 apparently we put our best foot forward with Bring Your Culture to Work day & “fairy bread” 🤷‍♀️#cosupervisionforthewin #aussie

@M_A_Neumann @ioannis_loukas Congrats Michelle!! So great to see this work out, especially your GFP mouse line! 😍

Really excited to share our preprint on BioRxiv 🎉 I am happy to have contributed by generating a Foxl2-GFP reporter mouse using CRISPR/Cas9 genome editing 🔬🧬🐁 Looking forward to see what impact the model will have in the future 🐭👩🏼‍🔬🔮 biorxiv.org/content/10.110…

@DrMigaleRoberta Brilliant work Robi!! 🎉

📢News from us🚨 Our #multiomics approach provides evidence of how the #ovary-specific transcription factor #FOXL2 may exert its differential roles throughout development by interacting with different protein partners #reprorocks #proteomics Preprint👇 biorxiv.org/content/10.110…

Check out our new review in @NatRevUrol where we discuss the genes driving sex development and genes involved in many types of DSD. Huge thanks to Ale, Nayla and Vince for all their hard work putting this together! @Hudson_Research nature.com/articles/s4158…

The 13th Congress of the Pacific Society for Reproductive Medicine is coming up soon, March 2023, in #sydney . Great chance to learn from global experts speaking on a wide variety of Reproductive Medicine topics. Don't miss the focused workshops especially the IVM Workshop!

@VeroMonchoAmor Congrats Vero!! 🤩🤩

The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent ge… pubmed.ncbi.nlm.nih.gov/36627412/

@gonen_nitzan @ScienceAdvances @TheCrick @ubarilan @institutpasteur @BadgeRobin Congratulations Nitzan!! So great to see this awesome work out 🎉🎉

🥳 Super excited to share our paper published at @ScienceAdvances. We generated an in vitro system to model the gonads and DSD patients. science.org/doi/10.1126/sc… It was a superb collaboration between @TheCrick @ubarilan @institutpasteur with @BadgeRobin and Anu Bashamboo. A 🧵 1/

@DrEllyJarred @Hudson_Research Congrats Elly!! 🎉

Last week I graduated from my PhD! Feeling very grateful to all the wonderful people @Hudson_Research - especially my supervisor A/Prof Patrick Western who supported me along the way. Excited to continue this work for my first year as a Postdoc! #PhD #PhDone #Graduation 🥂👩🏼‍🔬🧬

@bridgetarman @ReprodJournal @TDVFGroup @DrNatHannan @AlwisNatasha Congrats Bridget!! Looking forward to having a read 🤩

@ZacGermon @PrecisionMedUON @MattDun17 @DeVerrills @Dr_Heather_Lee @geoffdeiuliis Congrats Zac! 🎉🎉

Happy to have my PhD awarded to round out a great day at the @PrecisionMedUON symposium. Go team! A sincere thankyou to my mentors and supervisors @MattDun17 @DeVerrills @Dr_Heather_Lee @geoffdeiuliis and everyone along the way who made it possible.