Jack Lynch

Profoundly amped to join @IsomorphicLabs, the team and mission are next-level inspiring 😤😤😤

@Kpaxs @ifvictr 🐐🐐🐐

This is a man who has been haunted since childhood and built a billion dollar company as a side effect of trying to make the haunting stop.

@trq212 will you be at the London one?

hope to see you there!

@himanshustwts @srush_nlp nice

What a day for Context Compaction! > Morph trained a dedicated model for Context Compaction and yes, this is one of many usecases where SLMs fit and they shd win. > Cursor RLmaxxed again to self-summarize Composer and it effectively reduces error by 50% in Context Compaction.

@hannah_ahn @floguo @donaldjewkes @Reshusaur @iriscleung @harvpark @amandamhuang @jjxe_ @oscardumlao @Yash_471 @alessio_joseph beautiful shots!

I like hosting simply to aura maxx and cook for my friends — thanks to everyone that came to La Primavera 💗

@trq212 @travers00 I’m using both Opus 4.6 and GPT 5.4 for editing my novel and they are both useful, but in very different ways – they have dramatically different voices and even line-level, theme-level, characterization-level priorities.

@travers00 I think the models have a much more interesting and high dimensional texture than this GPT 5.4 is an excellent writer, Opus 4.6 is incredibly reliable at long running tasks they are very different but in hundreds of more subtle ways imo and it can change between generations

i find it kind of interesting that anthropic and openai's models and distribution seem inverted openai models are more reliable/accurate, more consistent, better for structured data processing = "inner loop" work claude models are more expressive, open-ended, better at taking abstract human input and orchestrating the final output = "outer loop" work yet openai owns the consumer endpoint with 900m weekly users on chatgpt - that looks like outer loop, but most consumer usage is actually simple, directed tasks. anthropic wins on api adoption and enterprise spend, which is increasingly "inner loop" more and more inference is shifting to background sub-agents, reliable always-on processing - that's where the volume is heading, even if the margin is largest at the outer loop. and more and more of the inner loop may get consumed by open source inference anyway

@fleurmeston wow

There’s no better view I could wake up to than that from my childhood bedroom window

Much cooler name than the “Landscraper”

@b1rdmania @PrimaMente Iso not weird enough damn 😔

15 weird London AI companies you've probably never heard of London's AI scene isn't just chatbots and SaaS. Some genuinely strange stuff happening. @PrimaMente – building "foundation models for the brain" to study Alzheimer's and Parkinson's. Hologen – frontier medical AI spinout tied to UCL/King's. Eric Schmidt involved. hologen.ai @baseimmune – AI-designed vaccines targeting rapidly mutating viruses. @RecursionPharma / @valence_ai – AI drug discovery platform combining chemistry, biology and machine learning. @CausalyAI – AI that reads scientific papers and maps biomedical knowledge graphs. Fractile – building new AI chip architecture. fractile.ai @mindgard – "red teaming" AI models to find vulnerabilities. @Limbic_ai – mental health triage AI used in NHS services. @LindusHealth – clinical trials run with AI infrastructure. Anima Health – AI triage platform for healthcare providers. animahealth.com AUAR – robots that build buildings. AI for automated construction. auar.io @testudoglobal – insurance for the AI economy. Isomorphic Labs – DeepMind spinout doing AI drug discovery. isomorphiclabs.com BenevolentAI – one of the earliest AI drug discovery companies. benevolent.com London AI ecosystem is weirder than people think. Still mapping more. Comment any i've missed so far. londonmaxxxing.com

This was such a fun and tense moment: I remember watching the model’s value function updating in real time as the matches unfolded. And ten years on we are using the same core concepts but making moves in chemical space, with equally mindblowing consequences 🤯

@CNN lmao

A post regarding the two individuals arrested for throwing homemade bombs outside of New York City Mayor Zohran Mamdani’s home failed to reflect the gravity of the incident thereby breaching the editorial standards we require for all our reporting. It has therefore been deleted.

my life is so easy

@romanhelmetguy How does the Book of Mormon beat out Moby Dick or Huck Finn

England’s national epic is Shakespeare’s Henriad. Beowulf is awesome, but it’s not a national epic of England. For one, it had zero cultural influence until it was rediscovered in the 19th century from a single 10th century manuscript. Before that, nobody was reading it. It’s never referenced in other English literature. Secondly, the events have approximately nothing to do with England. They take place in Scandinavia. Meanwhile Shakespeare’s Henriad tells the story of the Hundred Years War and England’s great warrior king Henry V. Also the War of the Roses and creation of the Tudors if you include all 8 plays. It was performed for kings. It was insanely popular in its day and remains hugely influential on the Anglo psyche. And its influence on the English language is second only to the King James Bible.

@tszzl 5.4 thinks you’d like it will send when completed!

@_lychrel omg

have to say claude is “tasteful” in a “high reddit modernist” way and new gpt is “tasteful” in a “early twitter schizophrenic” kind of way

@tszzl You’re in the epigraph btw!

@tszzl Using both as editors for my novel

Zooming in on the Taj Mahal

come join us on the applied ML team to make AI for drug discovery work in the real world for some of the most difficult problems in human biology isomorphiclabs.com/work-with-us

@IsomorphicLabs One of the great things about Iso is @bilaltwovec

“One of the great things about Iso is how interdisciplinary everyone is, people come from so many different backgrounds.” We spoke with Bilal Khan, Software Engineer at @IsomorphicLabs, about our unique, collaborative culture and frontier AI built to tackle the world's most complex problems. Watch the video and head to the comments to explore our current roles.

@femboyfirearms “Can It Run Doom” stops for no man

"We grew a human brain fused to a computer, sent it to a digital rendition of Hell, and gave it a gun"

Happy Holi