Aditi Merchant
32 posts
@aditimerch
BioE PhD student @stanford in the Hie Lab // ML for SynBio
Evo 2 is out in Nature today, showing that genome language models can predict and design across the full complexity of life, from phages to eukaryotes. A few surprises from the project, including how ignoring trillions of nucleotides was key to getting a good model. 🧵
What if we could autocomplete DNA based on function? Today in @Nature, we share semantic design—a strategy for function-guided design with genomic language models that leverages genomic context to create de novo genes with desired functions.🧵 nature.com/articles/s4158…
What if we could autocomplete DNA based on function? Today in @Nature, we share semantic design—a strategy for function-guided design with genomic language models that leverages genomic context to create de novo genes with desired functions.🧵 nature.com/articles/s4158…
What if we could autocomplete DNA based on function? Today in @Nature, we share semantic design—a strategy for function-guided design with genomic language models that leverages genomic context to create de novo genes with desired functions.🧵 nature.com/articles/s4158…
The ability to design antibodies against any protein of interest has major implications for medicine, biotech, and basic science. Today, we introduce Germinal, a pipeline for epitope-targeted de novo antibody design achieving 4–22% success rates with efficient experimental validation.
