Andy Posbe

Pikobodies vs. Potato Blight 🥊🥔 NLR–Nanobody Fusions Take on P. infestans 💥 🎤 Talk: Thurs July 17th, 16:35 🧾 Poster P-64: Tues 15th, Session 2 Poster’s up on Zenodo if you’re into spoilers 👀📎 zenodo.org/records/158479… #2025ISMPMI #OpenMPMI🌿

📢 We’re launching Proteina-Complexa — and after the Jensen keynote mention, we definitely had to post this thread now ;) Atomistic binder design with generative pretraining + test-time compute, plus large-scale wet-lab validation. Project page: research.nvidia.com/labs/genair/pr… 🧵 1/n

🧵 We ran the largest head-to-head benchmark of protein binder design methods in the wet lab. Project page: research.nvidia.com/labs/genair/pr… 1 million designs. 127 targets. RFdiffusion, BindCraft, BoltzGen, and Proteina-Complexa — all tested side by side.👇

HMA proteins produce 2',3'-cNMP signaling molecules and activate CNL-mediated immunity in rice biorxiv.org/content/10.648… #biorxiv_plants

asking Claude to create a prompt for my other Claude

🤞🏼😃

A unique Rubisco subunit from the hornwort plant carries a built-in extension that enables the enzyme to cluster into carbon-concentrating structures like algae, according to a new Science study—an innovation that successfully triggered similar condensates when introduced into Arabidopsis plants. The findings reveal a novel and evolutionarily independent solution for Rubisco condensation in land plants and open the door for engineering similar systems in agricultural crops to potentially boost nutrient efficiency and yield. 📄: scim.ag/3OQDBr4 #SciencePerspective: scim.ag/4udcg2k

@nobolly @HsuanPai1 Hehe I think I may have found it by accident 👀🫆🫆🫆🫆🫆

There’s a hidden gimmick on the website. If you want to unlock it, you’ll have to find me in person 🕵️🫆

#GGFungi2026 Call For Projects is now open for applications getgenome.net/callforproject… We will be holding an information session today 3rd March at 14:00 CET (08:00 Eastern US; 18:00 PKT). To sign up please complete this short form - forms.office.com/e/DssYYkkY9Z

@fedeaballay Congratulations Fede! 👏🏼

MY FIRST FIRST-AUTHOR PAPER is finally out!!!!! This is the end of such a great story: the paper on my undergrad thesis topic was finally published in EURJIC! I had the pleasure to work with such an amazing team and get this work done! …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ej…

The hardest part of protein engineering isn't just finding good mutations – it’s deciphering which ones combine synergistically. Today in @ScienceMagazine, we present MULTI-evolve, a framework for rapid multi-mutant protein engineering, validated across three diverse proteins.

📣 VACANCY: Postdoc/Research Assistant in the Kamoun group @kamounlab Join the team to work on the biology and applications of plant immune receptors 🌱 Apply online by 16 March 2026 tsl.ac.uk/working-at-tsl… #PlantSciJobs #PlantScience #STEMJobs

Step inside Project Genie: our experimental research prototype that lets you create, edit, and explore virtual worlds. 🌎

Huge congratulations to @HsuanPai1 on defending her PhD thesis by publication - a first at TSL. Such a PhD at UEA requires many years of research and many publications with significant intellectual input. A great example of what can happen when someone is given the space to grow.

A special day as we celebrate PhD of Dr Hsuan Pai @HsuanPai1 Pai has been a pillar @KamounLab @nobolly Labs over the years having contributed to research, method development, as well as science art and communication 🧬 🖼️ 😻 🙏 to viva examiners @EunyoungChae @Isabel_MonteG

📢 2 PhD Positions - Plant Immune Receptor Bioengineering at Imperial College London 🌱 Start: Oct 2026 📅 Deadline: 10 Feb 2026 🇬🇧 UK/settled status only 💰 Fully funded (48 months) ℹ️ shorturl.at/po61I #PlantImmunity #PlantPathology 🙏 Share with interested candidates!

Why I’m genetically engineering a rainbow flower… And how a Russian fairy tale inspired the idea 🧵

Can you read 900 words per minute? Try it.

First image of the Moon in 2026! A 96% waxing gibbous phase GT71, x2.5 PowerMate and Saturn C. Showing some mineral colours. @MoonHourSocial #astronomy #Astrophotography

The Pik NLR pair accumulates at the plasma membrane as a hetero-oligomeric sensor-helper immune protein complex prior to activation biorxiv.org/content/10.648… #biorxiv_plants