alephh

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alephh

alephh

@alephh

Entrepreneur, self-improvement, strategy game coder, WW2/History buff, OMAD keto, avid book/research reader, quantum biology/physiology, minimalist✌️☀🧊🦄🇫🇮🧩

Electromagnetic Quantum Field Katılım Ağustos 2007
45 Takip Edilen385 Takipçiler
alephh
alephh@alephh·
Association between triglyceride-glucose index and all-cause mortality in transcatheter aortic valve replacement – a per-unit increase in the TyG index was associated with a 41% higher all-cause mortality risk (HR 1.41, 95% CI 1.03-1.93, p = 0.030) pubmed.ncbi.nlm.nih.gov/39313838/
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alephh
alephh@alephh·
Trajectories of triglyceride-glucose index changes and their association with all-cause mortality: competing risk analysis – Compared with stable group, adjusted hazard ratios for all-cause mortality were 1.09 in increasing group and 1.23 for CVD mortality pubmed.ncbi.nlm.nih.gov/39407266/
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alephh
alephh@alephh·
Predictive Value of Triglyceride-Glucose Index for All-Cause Mortality in Diabetes – Participants in top quintile had higher all-cause mortality HR=1.38 – Higher TyG associated with higher all-cause mortality (per SD increment HR=1.52) when above threshold pubmed.ncbi.nlm.nih.gov/39479579/
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alephh
alephh@alephh·
Triglyceride-glucose index: a predictor of mortality risk among myocardial infarction survivors – mortality rates increased when the TyG index surpassed these low/high thresholds (HR = 1.38, 1.08-1.76; HR = 1.56, 1.02-2.38) pubmed.ncbi.nlm.nih.gov/39528543/
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alephh
alephh@alephh·
Correlation of triglyceride-glucose index and heart rate with 28-day all-cause mortality in severely ill patients: analysis of MIMIC-IV database – individuals with a heightened TyG-i and elevated HR had highest 28-day ACM (Hazard Ratio 1.70, P<0.001) pubmed.ncbi.nlm.nih.gov/39574113/
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alephh
alephh@alephh·
Triglyceride index as a predictor of mortality after cardiac surgery – TyG index-based model outperformed established scoring systems in predicting mortality – Higher TyG index levels were associated with increased mortality risk (hazard ratio HR=1.206 pubmed.ncbi.nlm.nih.gov/39620137/
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alephh
alephh@alephh·
@richcollins Yes, fatty foods trigger the same signal for 60 seconds (gut defense wall is opened to take in nutrients, possible letting in the nasty 740,000,000 various different metabolites gutbiome makes, eating is a crisis), Semaglutide brutally forces the that signal for 600,000 seconds
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Rich Collins
Rich Collins@richcollins·
@alephh So eating a fatty meal, which also stimulates glp1, has the same effect?
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alephh
alephh@alephh·
Ozempic Associated with 10X Erectile Dysfunction & Hypogonadism in Non-Diabetic Males – Men with semaglutide prescription significantly more likely diagnosed with ED and/or prescribed PDE5i 1.4% vs males who were never prescribed glp1 0.14% (RR=10.0; 3–32) academic.oup.com/jsm/article/21…
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alephh
alephh@alephh·
@KetoCarnivore Most likely because allulose increases cytosolic calcium concentration in POMC neurons of arcuate nucleus in hypothalamus
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L. Amber O'Hearn
L. Amber O'Hearn@KetoCarnivore·
Similar experience regarding ketones. What's the mechanism here?
Leo Abstract@Leo_Abstract

@KetoCarnivore @SEPfieldPatient @exfatloss @EluGueva @MikeJon51688372 @CarnivoreAugust @Libertas2008 @theswansjr @Boio89 @markeatsmeat yeah allulose cranks my ketones like nothing else i've tried. too bad it's a weird artificial* laxative. * this word means nothing, like 'natural' as used by Big Allulose. uranium-235 is 'naturally' occuring in seawater, but if you bind a bunch out it's uhhh bad for you.

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alephh
alephh@alephh·
🔃
ART
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alephh
alephh@alephh·
Listen to the professor
Retsef Levi@RetsefL

The abstract of this new published study by the US CDC isn't honest re the results! Babies & children (6 mo to 4 y) who received Pfizer COVID vaccine were 3.57 times more likely to have symptomatic COVID! Prior infection provides strong and long term protection! For the longest time the CDC denied the basic concept of natural immunity and still recommends ineffective and dangerous mRNA vaccines to babies & young children with zero risk!

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alephh
alephh@alephh·
Cell biology has evolved 4 billion years: instead of nonstop building new pathways, nature mostly repurposes existing ones, leading to complex mess where dozens of processes by various tissues use a single pathway. So, any drug inevitably twists dozens of things while fixing one.
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alephh
alephh@alephh·
Roughly half of the time I wake up in same exact position I began sleeping, usually 6h later, 8 if I pushed myself mentally/physically. Mastering sleep is hard. Cool room helps but with enough glycine/melatonin body cools itself enough to allow heat-sensitive enzymes do hard work
alephh@alephh

2 "best" positions to sleep –Natural:on right side, hard NONCOMPRESSING pillow PRECISELY the height you don't keel over –Unnatural:on back, expose belly=easy prey, roll of paper towels type pillow. Spine CT scans show wonders. Sadly can take 2 months of hell to learn if back pain

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alephh
alephh@alephh·
2 "best" positions to sleep –Natural:on right side, hard NONCOMPRESSING pillow PRECISELY the height you don't keel over –Unnatural:on back, expose belly=easy prey, roll of paper towels type pillow. Spine CT scans show wonders. Sadly can take 2 months of hell to learn if back pain
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alephh
alephh@alephh·
Melatonin regulates circadian rhythm to ameliorate postoperative sleep disorder & neurobehavioral abnormalities in aged mice – significant efficacy in ameliorating PSD & delirium & restoring circadian rhythm, reversing MEL receptor & ERK/CREB abnormalities pubmed.ncbi.nlm.nih.gov/37736695/
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alephh
alephh@alephh·
Effects of short-chain fatty acid-butyrate on circadian-clock genes, sleep quality, and inflammation in ulcerative colitis: a double-blind RCT – reducing biomarkers of inflammation, upregulation of circadian-clock genes and improving sleep quality pubmed.ncbi.nlm.nih.gov/39003477/
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alephh
alephh@alephh·
Are there effects of light exposure on daytime sleep for rotating shift nurses after night shift?: an EEG power analysis – During daytime sleep, lower sigma wave power in N2 sleep was observed under light exposure compared to no light exposure pubmed.ncbi.nlm.nih.gov/38601092/
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alephh
alephh@alephh·
@richcollins GLP1 in brain is fear/danger signal, obviously body shuts down reproduction if it is escaping a tiger
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Rich Collins
Rich Collins@richcollins·
@alephh Compared to men eating same amount of calories?
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Keşfet

@richcollins @KetoCarnivore @elonmusk @BarackObama @taylorswift13 @cristiano @BillGates @NASA