Alexander S. Hauser

Our new paper "Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes " is out in @NatMetabolism nature.com/articles/s4225… We demonstrate that β-arrestin is central to the function of the #GIP receptor in vitro/vivo. 1/n 🧵👇

Interesting thoughts here: The future of reviews: Will LLMs render them obsolete?: EMBO reports: embopress.org/doi/full/10.10…

Contribute to the EU-funded Biodiversity2Drugs project, predicting protein-protein interactions across species! 🧬🤖 gruber-lab.com/b2d 🔍 PhD required (bioinformatics, ML, data science, etc.) 🛠️ Python/R, protein models, big data handling 📍 Copenhagen | Start: May 2025

🚨 We’re hiring a #postdoc in Bioinformatics/Data Science/ML! 🚨 Join us in Copenhagen for a postdoc exploring nature-derived drug discovery with AI/ML, genomics, and structural biology. link

@ClemmensenC @Metabolcenter @ERC_Research @UCPH_health Congrats and good luck with the project!

Honored and thankful to receive the @ERC_Research Consolidator Grant! This reflects more than 7 years of collective effort in my lab. Grateful for the incredible support from @Metabolcenter, @UCPH_health, and the many people who supported us along the way! healthsciences.ku.dk/newsfaculty-ne…

@Z_GerhartHines @simonrasmu @Nature Great work! Congrats.

Our new paper, "NK2R control of energy expenditure and feeding to treat metabolic diseases," is out today in @Nature. Here we identify a single receptor that can both peripherally increase energy expenditure and centrally suppress appetite. nature.com/articles/s4158… 1/12 🧵👇

@DelemotteLab Big congratulations and welcome back!

@NicoleAPerry1 @UofGlasgow Great news - congratz!

I'm excited to announce that I've officially accepted a Lecturer (Research & Teaching) position at the University of Glasgow's School of Molecular Biosciences! Starting March 2025, my lab will study the role of adhesion GPCRs in neuropsychiatric disorders. @UofGlasgow

10 more days to apply - come join us in Copenhagen!

🚨 🔬 We’re hiring a #postdoc in molecular #pharmacology and #pharmacogenomics! 🧬 If you have a passion for cutting-edge research and a drive to explore new frontiers in drug discovery and molecular mechanisms, this could be the perfect fit for you! 💊✨ employment.ku.dk/all-vacancies/…

@cyclic_Andreas @UnimedizinMainz @uni_mainz Congrats Andreas, great news.

I have joined the University Medical Center in Mainz @UnimedizinMainz @uni_mainz as #Professor and #Chair of #Pharmacology I’m very grateful to be given the opportunity to build a #department dedicated to #cell #signaling #research including #GPCRs I will hire on all levels!

@Filip_Knop @NatMetabolism Thanks for highlighting!

Here, by combining in vitro pharmacological characterization of 47 GIPR variants with burden testing of clinical phenotypes and in vivo studies, the importance of β-arrestin recruitment in GIPR function is highlighted. nature.com/articles/s4225… @NatMetabolism

@ClemmensenC @NatMetabolism Thank you Christoffer!

@alexshauser @NatMetabolism Congrats Alex and co-author team on this important contribution to the incretin field 👍

Our new paper "Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes " is out in @NatMetabolism nature.com/articles/s4225… We demonstrate that β-arrestin is central to the function of the #GIP receptor in vitro/vivo. 1/n 🧵👇

/10 Thanks also to the comments and guidance provided by the editors and reviewers and to the support from @koebenhavns_uni and @UCPH_health

/10 Incredible efforts by the three first authors Sheyma, Kimmie, and Jakob plus help by Peter and Alessandro and all the people involved in this massive collaborative effort especially the teams around Mette Rosenkilde Niels Grarup, Volker Lauschke, and Jonathan E. Campbell.