Andrew Luskin

This is one of the craziest ideas I've ever seen. He converted a drawing of a bird into a spectrogram (PNG -> Soundwave) then played it to a Starling who sung it back reproducing the PNG. Using the birds brain as a hard drive with 2mbps read write speed. youtube.com/watch?si=HMtVd…

Thrilled to announce that our paper is now finally out! 🎉We combine scRNAseq, 2p imaging, ephys, and behavior to understand the role of lateral septal Nts neurons in opioid withdrawal. Curious about the septum and addiction? Give it a read👇 cell.com/neuron/fulltex…

Nature research paper: Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours go.nature.com/4m6h5Xl

@SChenlab Thanks!

@aluskin beautiful work!!

New paper on arousal in the brain! What controls the controller?

@willgiardino Thanks!

@baseliu Thanks Aiste!

@aluskin Congrats , Andrew! This is such a good paper!

@dilithium21 @mbruchas @_MadisonMMartin @kelseybarcomb @mouse_braind @gstuber @GuLiangcai Institutes include @UWAnesthPainMed, @UWPharmacology, @UWproteindesign, @seattlechildren, @UWPsychology , @UWBiochemistry, @CUAnschutz, @BioStructureUW - thank you all for making this possible!

@dilithium21 @mbruchas @_MadisonMMartin We worked on electrophysiology with @kelseybarcomb and Chris Ford; single-cell sequencing with @mouse_braind and @gstuber, spatial sequencing with Xiaonan Fu, Li Sun, Lei Gao, and @GuLiangcai; and 3-D imaging with Alexandria Murry and Sam Golden

@nabeelqu form determines function; neural processing is dependent on complex spatial/temporal dynamics - this is why neurons have different shapes, form different layers, etc. and many modulatory effects are not strictly synaptic but depend on volumetric release or spill-out effects

@nabeelqu ulkar nailed it but I'll add: -easier to wire logically within biological constraints -easier to learn/repair etc. bc adult neurons don't like to do huge morphological changes -shorter transmission lengths increases speed, decreases size, decreases cellular stress in long cells

Naive neuroscience q: is there a *principled* reason why the brain has different regions, or is it mostly an artifact of evolutionary history? (If you were to 'refactor' the brain, could it just be a giant blob of neurons/synapses, or are there good reasons for specialization?)