Ankit Dutta

Excited to share our new review on single cell genomics and applications in multiple myeloma! @NatRevClinOncol nature.com/articles/s4157… #mmsm #labghobrial @JbAlberge @RomanosSP @gaddyg @IreneGhobrial

Excited to share a new preprint from @TCupedo lab where we used #scRNAseq and functional studies to investigate the composition and function of the bone marrow #NKcell compartment in #myeloma at diagnosis, during treatment, and at relapse. biorxiv.org/content/10.110…

Nature research paper: Evolution of a minimal cell go.nature.com/46D4GSO

Honored to write this commentary with my amazing mentor, Dr. Anderson, on determinants of response & resistance to bispecific t-cell engagers in #MultipleMyeloma #mmsm. So much to learn about the complexity of the immune system and optimizing TCEs! @DanaFarber @DanaFarberNews

This week in Nature: Human pangenome – data from 47 individuals combine to create reference resource that reflects human diversity. Browse the full issue: nature.com/nature/volumes…

How my training helps me to address health disparities in multiple myeloma go.nature.com/3HZTaGE

‼️ The PANGEA Model is out now @TheLancetHaem ‼️ A 🧵on how PANGEA improves prediction accuracy of MGUS & SMM progression to #MultipleMyeloma & is the 1st model that is #personalized to the individual #mmsm patient! @LabGhobrial @DanaFarber | 1/ sciencedirect.com/science/articl…

From the February issue— Genomic profiling of circulating #multiplemyeloma cells, by @ankitkdutta, @JbAlberge, @gaddyg, @IreneGhobrial et al. bit.ly/3Ih5NMN @getz_lab @LabGhobrial @DanaFarber @broadinstitute #LiquidBiopsy #CirculatingTumorCells

The Gadrial retreat (Getz+Ghobrial labs) was a great success ⁦@gaddyg⁩ ⁦@getz_lab⁩ ⁦@LabGhobrial⁩ ⁦@PromiseStudy⁩ #mmsm. Great ideas to tackle scientific challenges. Thank you all for the amazing work you do.

Nice @CD_AACR #MMsm paper by @IreneGhobrial lab! # CTCs clearly increased from MGUS to SMM marching up 20/2/20. More importantly, genetic profiling of 🩸 CTCs identified all BMBx FISH findings + more. Given 🐠 not always done / not as sensitive, possible game changer some day!

MinimuMM-seq: Genome Sequencing of #CirculatingTumorCells for Minimally Invasive Molecular Characterization of #MultipleMyeloma Pathology, by @ankitkdutta, @JbAlberge, @gaddyg, @getz_lab, @IreneGhobrial et al. bit.ly/3Ikzr5v @LabGhobrial @DanaFarber @broadinstitute

A new technique developed by @DanaFarber researchers offers a promising ability to detect and analyze multiple myeloma tumor cells using a simple blood sample. dana-farber.org/newsroom/news-…

MinimuMM-seq: Genome Sequencing of #CirculatingTumorCells for Minimally Invasive Molecular Characterization of #MultipleMyeloma Pathology, by @ankitkdutta, @JbAlberge, @gaddyg, @getz_lab, @IreneGhobrial et al. bit.ly/3FLN8c1 @LabGhobrial @DanaFarber @broadinstitute

Looked at today’s #ASH22 posters before leaving - if you stop by #4457 presented by @ankitkdutta check out the recent @CD_AACR paper on this work in #MultipleMyeloma aacrjournals.org/cancerdiscover…

Presenting tonight our work on MinimuMM-seq #ASH22 Poster 4457! Come by to discuss detection and genomic profiling of circulating tumour cells for key myeloma biomarkers! @JbAlberge @IreneGhobrial @LabGhobrial @getz_lab #mmsm

Congrats to ⁦@ankitkdutta⁩ on his #ASH22 Abstract Achievement Award on MinimuMM-Seq work #mmsm ⁦@IreneGhobrial⁩ ⁦@LabGhobrial⁩ ⁦@gaddyg⁩ #mmsm

Beautiful work by Liz Lightbody at #ASH22 showing the power and promises of CTC #scRNAseq in #myeloma and discovering new features and biology of MM #CTCs in the process ⁦@LabGhobrial⁩ ⁦@IreneGhobrial⁩ #mmsm

Single cell sequencing of circulating tumor cells ⁦@LabGhobrial⁩ ⁦@getz_lab⁩ ⁦@DanaFarber⁩ #ash22 ⁦@BrunoPaiva_UNAV⁩. CTCs in predicting progression but not just the numbers

📣First of many CTC abstracts at #ASH22 #mmsm Super study by @IreneGhobrial @LabGhobrial with thousands of single CTCs being sequenced. Consistent results with Spanish data @juanjogrcs I continue believing that these data will deliver pathways to prevent disease dissemination!

Excellent presentation on molecular profiling of circulating tumour cells in precursor multiple myeloma from Dr. Elizabeth Lightbody! Towards an improved understanding of CTC biology/extravasation, and clinical utility of liquid biopsies for patients! @LabGhobrial #mmsm #ASH22

First of a number of presentations at #ASH22 by ⁦@LabGhobrial⁩ on this amazing #scRNAseq cohort of progression from MGUS->MM, the largest to date. Nicely done by Junko #mmsm ⁦@IreneGhobrial⁩ ⁦@gaddyg⁩