Annie Silk

@MunTheLoon @GMA @LurieCancer @NorthwesternMed Amazing story, Su!!

Another illuminating annual meeting! #SITC24. Two themes are spatial profiling and paying close attention to the tumor-stroma invasive margin.

The @sitcancer NMSC CPG rapid update v1.1 includes new/revised clinical recommendations pertaining to additional anti-PD-1 therapies for patients with CSCC and MCC. More information: sitcancer.org/NMSC-guideline #SITCGuidelines #NMSC #CSCC #MCC #Immunotherapy

#ipatasertib is a drug showing great promise against #glioblastoma, an incredibly aggressive #braintumour. New treatments are urgently needed with innovations against #braincancer sadly few and far between. #acurecantwait bit.ly/3tgdgTO

💊 NEWS: The immunotherapy drug #atezolizumab together with the precision drug #ipatasertib could offer a new way of treating some people with aggressive #BrainCancer, early results from a Phase I trial led by the ICR and @royalmarsdenNHS suggest. #AACR21 zcu.io/XUwE

Agree with the quotes by Dr. Ribas in here (Adam had a nice writeup in the Stat #AACR21 email as well). Historic not only for uveal melanoma, but also b/c it appears to be the first T-cell engager truly ready for commercial prime time since Blincyto. onclive.com/view/frontline…

Early trial shows promise aiming a modified cold-sore virus against brain tumors in children statnews.com/2021/04/10/ear… Our first #AACR21 story today and a really hopeful one bc this is a devastating cancer. Well told by @cooney_liz

Professor of Bioengineering in Oncology Stephen T. Wong, PhD and Jianting Sheng, PhD believe a shorter survival time after #BrM diagnosis may indicate a unique innate ability of #TNBC tumor cells to adapt to the brain.

😳😳 impressive results on Nivo+chemo neoadj. for NSCLC!! (CM-816) Confirm efficacy of ICIs in RR and ctDNA clearence correlate!! 👇👇 #AACR21 #AACR2021 #NSCLC

I'm devastated by the loss of my close friend for the past 23 years, Leah Zallman. Leah was kind, brilliant, hilarious... a wonderful friend and an even better mother. So hard for her family, her friends, her patients, and her colleagues to accept this sudden and tragic loss.

@FunchainMD @NIH_LRP @theNCI @NIH Well deserved, Pauline. Congrats!

Holy Fauci Almighty, I got an @NIH_LRP award! Thank you @theNCI @NIH! For all of you who know how much and for how long I have loved 🧬, receiving this award notification hit me more than I even thought. Grateful and ready to serve 🧗‍♀️ #WomenInMedicine #WomenInSTEM 💪👊

It took Dr. Lisa Cook ten years to get her paper published. That is perseverance through injustice.

Wear a mask.

A group of Black men in Louisville KY formed a human shield around a white cop who got separated from his unit, to protect him from angry protesters. Can anyone post a picture of a group of white cops forming a human shield & protecting a Black man from police violence?

@DrChoueiri I almost got rid of mine-- now I'm glad I didn't

The good old scrubs are back. #COVID19

In case you are wondering about IL-6 inhibitor Tociluzumab effect in #COVID19 serious infections: N=20. 19/20 discharged in 2 weeks. Improvement in lung lesions. Reduction in fever/C-reactive protein, increase O2 saturation among others. LINK to paper chinaxiv.org/abs/202003.000…

@AndrewZloza #NewYearsResolution

@annwsilkmd And if it also worked in situations where pd-1/pd-l1 blockade fails? ... And in combination with these its effects were even stronger? Then we would have to spend 2020 figuring out the best way to translate it to patients! Can't wait!!!

What if there were a safe and cheap injection that triples intratumoral cross-priming DCs, increases tumor-specific CD8s by an order of magnitude (Fig. 2), and synergizes with anti-PD-1 (Fig. 3)? It's already FDA-approved, but not for treating cancer!  pnas.org/content/early/…

New @Health_Affairs study suggests efficiency & public health may be the best arguments for #SinglePayer in the US. bit.ly/2r3ct7E

Nevada's legislature just passed a radical plan to let anybody sign up for Medicaid - Vox apple.news/A8IDBEMeMToq1s…