antnerves

The collaboration between @VariantBio and @novonordisk will trigger our long term benefit sharing program for the first time! Read about it in the NYT. nytimes.com/2025/01/07/hea…

Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis @Nature from Tetsuji Kakutani & colleagues - beautiful insights into control of transposon insertion into the centromeres nature.com/articles/s4158…

New blog: Modified Base Best Practices & Benchmarking for @nanopore 🧬 sequencing Includes: * Raw POD5 files for synthetic ground truth strands * Modified base calling best practices * Modkit recommendations Check it out: labs.epi2me.io/mod-validation… #methylation #bioinformatics

.@nanopore today announced that @RosemaryDokos has been appointed Chief Product & Marketing Officer & Lakmal Jayasinghe as Chief Scientific Officer, effective immediately. Rosemary & Lakmal succeeded Clive Brown as Chief Officer of Technology, Innovation, & Products. Read more: bit.ly/3O4ulvQ

It is my absolute pleasure to share my incredible postdoc Dawei's @amaizeingcorn manuscript on epigenetics and aging in Arabidopsis. It is the work I am most proud of thus far in my career, and every figure has a breakthrough that we are excited about biorxiv.org/cgi/content/sh…

Super exciting to see what the future holds for nanopore beyond DNA and RNA sequencing nature.com/articles/s4158…

This paper led by Dr. Atsushi Shimada is out @NaturePlants! Centromere function can be dependent on a few TEs, and in RNAi mutants, small RNAs targetting these TEs are enough to reestablish normal chromosome segregation! Crazy! nature.com/articles/s4147…

So great to see this paper out in @Nature. Beautiful molecular characterization of a new toxin-antidote drive system in maize, led by Ben berube, with assistance from Martienssen lab @antnerves @CrisAlves_bio @BioJlynn and collaborators @arminscheben @jrossibarra Jerry Kermicle

I'm thrilled to share that I'll be joining @Yale as an Assistant Professor in the Department of Molecular, Cell, and Developmental Biology @MCDB_Yale in January 2025! (1/3)

H3K4me1 recruits DNA repair proteins in plants academic.oup.com/plcell/article… interesting findings! @Grey_Monroe @ThePlantCell

Friends, we are introducing LiftOn, a homology-based genome annotator that uses a protein-centric algorithm, considering both DNA & protein alignments to improve genome annotation lift-over 1/9 @StevenSalzberg1 @elapertea @JakobHeinz9 @alaina_shumate @celinehohzm @alan_mayonnaise

A hallmark of sex is each parent transmits half of their genome through a recombined egg or sperm. What if this was not the case? Check our new paper @NatureGenet where we break this rule via diploid clonal gametes and develop polyploid genome design nature.com/articles/s4158…

The MaizeCODE paper is on BioRXiv! New insights on enhancers in plants and a lot of data for every maize (epi)geneticist to play with, including on teosinte, the ancestor of maize. A big team effort, very grateful to everyone involved! biorxiv.org/content/10.110…

First major work fully made in the laboratory is out in @biorxivpreprint: biorxiv.org/content/10.110…. We found that DNA methylation allows recurrent endogenization of giant virus in a protist🦠 closely related to animals, large scale virus and eukaryotic host genomic mixture.🧵 1/10

Really thankful to start the year in such a great way: Our paper is out today! 🥳 Congrats to all the authors for their hard work, and thanks to the editors & reviewers for their insight on how to improve it! 🧵1/3 nature.com/articles/s4147…

Gene expression involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. We developed ChIP-DIP – a method for simultaneous, genome-wide mapping of hundreds of DNA-protein interactions in a single experiment. biorxiv.org/content/10.110…

Join our department! Please share to potential candidates

My PhD research on Arabidopsis mC readers is finally out in @biorxivpreprint. It took a long time, a lot of work, and there are still many open questions, but thanks to @JamesPBLloyd @ry_lister and great collaborators it's out there! biorxiv.org/content/10.110…

Check out our new preprint! We sequence the genome of the Living Fossil Wollemi Pine! Thanks to everyone involved in this collaborative effort! biorxiv.org/content/10.110…