Antonino Zito

Excited to share a local maximum of my grad school roller coaster ride: our paper “The origins and functional effects of postzygotic mutations throughout the human life span” is now published in @sciencemagazine: science.org/doi/10.1126/sc…. 1/4

Come and join my group in Milan! Five year research position. Open to multiple profiles. Machine learning researchers interested in large-scale imaging, genetics and health-research apply! Attractive 90% tax exemption for people new or returning to Italy. careers.humantechnopole.it/o/bioinformati…

@TiphCMartin @PLOSGenetics @kerrin_small @A_L_Roberts @_alesssia @Julia_Moustafa @MarioFalchi Thank you Tiphaine!

@anto_zito @PLOSGenetics @kerrin_small @A_L_Roberts @_alesssia @Julia_Moustafa @MarioFalchi Happy to hear that your paper is out! Well done!

Our paper on Escape from X-inactivation is now out in @PLOSGenetics. We measured escape in multiple tissues and assessed tissue-specificity, variability and other features journals.plos.org/plosgenetics/a… Thanks @kerrin_small @A_L_Roberts @_alesssia @Julia_Moustafa @MarioFalchi + others

@arthur5ko Thank you Arthur

@anto_zito Congrats Antonino!

Our paper led by @anto_zito investigating variation in escape from X-inactivation across tissues, individuals and twin pairs is now published in @PlosGenetics dx.plos.org/10.1371/journa… Many thanks to @A_L_Roberts @_alesssia @Julia_Moustafa @MarioFalchi @TwinsUKres

Age-acquired X-inactivation skew in blood as potential biomarker of chronic disease risk. Congrats @A_L_Roberts & @kerrin_small!

Ever wondered what could go awry when your body copies a 6 billion letter message (i.e. your #genome) 1E16 times over your lifetime? If so, checkout our #preprint on the origins and functional effects of #mutations throughout the human lifespan. bit.ly/3yT5KBz

We conducted a transcriptomic survey to study properties of escape from X-inactivation across tissues and cells in female twins. @A_L_Roberts @_alesssia @Julia_Moustafa @MarioFalchi @kerrin_small @TwinsUKres biorxiv.org/content/10.110…

Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable biorxiv.org/cgi/content/sh… #bioRxiv

@anavinuela @kerrin_small Thank you Ana

#ASHG19, Jian Hu from UPENN presents t-DESC: a new transfer learning method that learns from known gene expression signatures to classify and cluster target single-cell data. This may help to cluster cell types in cases when only a few cells are available or seq depth is low.

Nice #LPSHG member reunion yesterday night with @antje_grotz @pwhook and @niekdeklein at #ASHG19 Houston. Hope to see @arthur5ko @D_Westergaard @tomsasani @michaelkosicki @mp3r41c @Jack_Kosmicki @wcmcfadden @kyokowtnb @anilpsori and all others at #ASHG2020

Does the #gut #metagenome composition influence host systemic #metabolism? How important are microbial functions compared to single species? Find the answers in our latest @TwinsUKres study, just out on @NatureComms: nature.com/articles/s4146…

Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus @A_L_Roberts @Chris_Odhams go.nature.com/2EdvygP

Seeking candidates for a 2-year postdoc @KingsCollegeLon on epigenetics and diet in human cohorts & diet trials in my group, as part of @JPI_HDHL funded international consortium grant. Closes April 10 - more details here bit.ly/2uGEUwA #epigenetics #nutrition Please RT

Six #PhD positions available at @KingsCollegeLon in the Biomedical Science & Data Analysis programme. Many great projects - including one in my lab on gene expression with @alanjhodgkinson Closing date is April 9th - details here bit.ly/2Tr86S9

Heritability of skewed X-inactivation in female twins is tissue-specific and dependent on age biorxiv.org/cgi/content/sh… #biorxiv_genetic

Heritability of skewed X-inactivation in female twins is tissue-specific and dependent on age biorxiv.org/cgi/content/sh… #bioRxiv

What do megadomains and superloops do on the X? For answers, see our latest paper just published ... nature.com/articles/s4146…