@VivekHariSunda1 @shivaprasad_pv @NCBS_Bangalore @NaturePlants Congrats all of you for this brilliant work!
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Asha Mary Joseph
283 posts
Asha Mary Joseph
@ashamjos
Project Scientist @dnarepairlab @NCBS_Bangalore || PhD @iiscbangalore || Molecular Microbiologist || Mom, curly girl, homemaker, DIY buff & road tripper
Bangalore Katılım Ağustos 2014
282 Takip Edilen251 Takipçiler
Excited to share the second part of my Ph.D. work with @shivaprasad_pv lab @NCBS_Bangalore. Histones are sculptures of (epi)genomic architecture and we here report the histone H4 variant (H4.V) in Oryza - nature.com/articles/s4147…. @NaturePlants.
Shiva prasad@shivaprasad_pv
Delighted to share this. A novel H4 variant that modulates chromatin to mediate salt stress response. This mammoth work was driven to perfection by @VivekHariSunda1, a wonderful PhD student who also taught me. We report its CryoEM structure & unusual chemistry @NCBS_Bangalore 1/3
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Check out the previous thread on our preprint. x.com/ashamjos/statu…
We went on to dissect the specific reason behind replisome speed variations. All of this at the level of single cells!
Asha Mary Joseph@ashamjos
Delighted to share this new preprint from Anjana Badrinarayanan @anjbadri lab. By assessing replication dynamics at the level of single cells, we reveal the intricate relationship between nutrient status and rates of genome duplication in bacteria. biorxiv.org/content/10.110…
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Cheers to the entire team from @anjbadri lab. Elated to share my very first corresponding author manuscript!
Anjana Badrinarayanan@anjbadri
Now published @CurrentBiology. Happy to share latest work from the lab led by @ashamjos and @Adhikashreni1, describing replisome speed variation in Caulobacter! cell.com/current-biolog…
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Asha Mary Joseph retweetledi
Thank you to the fantastic speakers who presented today at our first meeting!
We are now accepting submissions for our second meeting on April 7th.
Submission link : forms.gle/SBeQeAp9MR2UcV…
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Asha Mary Joseph retweetledi
Asha Mary Joseph retweetledi
When does a DNA polymerase degrade DNA? Read Akshaya’s latest work from the lab to find out more!
EMBO Reports@emboreports
Akshaya Seshadri and Anjana Badrinarayanan @anjbadri @NCBS_Bangalore @TIFRScience show that #exonuclease action of replicative #polymerase gamma drives damage-induced #mitochondria #DNA clearance. A new mechanism of mtDNA clearance following damage. embopress.org/doi/full/10.10…
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New preprint alert!
Aditya Kamat@Aditya_Kamat96
There's more to SOS response timing than the LexA repressor. In our preprint from the Anjana Badrinarayanan @anjbadri Lab, we uncover a new regulatory layer that imparts temporal structure to the bacterial SOS response. biorxiv.org/content/10.110…
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@tapomoy89 @NCBS_Bangalore @ESoftbio @padmanabh97 @NatureComms @DeepaAgashe @c_kurzthaler Beautiful story! Congrats all of you!
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Asha Mary Joseph retweetledi
Latest work from our group @Esoftbio @NCBS_Bangalore, led by Sree @padmanabh97, is out today in @NatureComms! In colab with @DeepaAgashe @c_kurzthaler we report that the physical confinement acts as a selective pressure on bacterial growth in 3D! [1/16]
tinyurl.com/mvbdm3ue
GIF
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Asha Mary Joseph retweetledi
Registration is OPEN for 2025 Bacterial and Archaeal Cell Biology and Development @GordonConf and GRS. This will be oversubscribed, so register ASAP. We have an amazing lineup of speakers and discussion leaders.
Apply now - grc.org/bacterial-cell…
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Asha Mary Joseph retweetledi
🌟 NEW! 🌟
Our latest comic with @TinkleMagazine featuring Dr Anjana Badrinarayan is out now!
Check out the comic and do let us know your thoughts in the comments below!
#sciencecomics #womeninscience #womeninSTEM
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Delighted to share this new preprint from Anjana Badrinarayanan @anjbadri lab.
By assessing replication dynamics at the level of single cells, we reveal the intricate relationship between nutrient status and rates of genome duplication in bacteria.
biorxiv.org/content/10.110…
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Asha Mary Joseph retweetledi
🌟NEW COMIC ALERT!🌟
The fourth comic of our collaboration with @TinkleMagazine features the inspiring Prof @hiyaa_ghosh, a neuroscientist at NCBS🧠
Check out the comic and share your thoughts in the comments below! #sciencecomics #womeninscience #womeninSTEM #scicomm
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Asha Mary Joseph retweetledi
1/ 🌟 Transitioning to Life Science? Connect with industry experts! Join our unique Pitching Event. 🚀
Meet industry leaders, network, and discover potential employers. Showcase your skills and share your CV! 📄
🎯 Register: forms.gle/5jJXftPnduLayn…
RT to spread the word
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This work was led by a super-talented graduate student Inchara @Adhikashreni1 who initiated this project as part of her Master's dissertation and was supported by Sneha Phadke, another graduate student in the lab.
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Nutrient-dependent regulation of replication is distinct from stress-induced replication slow-down, and is likely a strategy to cope with transient fluctuations in the environment.
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