avinash karkada

20 posts

avinash karkada

avinash karkada

@avinashkarkada

Katılım Nisan 2014
41 Takip Edilen12 Takipçiler
avinash karkada retweetledi
Kesavardan S
Kesavardan S@keshu_VRimmCh·
Glad to see this research highlight in @NatureInd on our recent work. The current 2.3.4.4b clade #H5N1 is unusual and spreading rapidly in mammals and shows human adapting potential, a #OneHealth concern, needs more attention. nature.com/articles/d4415…
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avinash karkada retweetledi
IISc Bangalore
IISc Bangalore@iiscbangalore·
A new study by researchers at IISc offers insights into cell death regulation by viruses like SARS-CoV-2, and how bats and humans respond differently to tricks that such viruses use to manipulate the host’s defense. iisc.ac.in/events/how-bat… #IIScresearch
IISc Bangalore tweet media
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avinash karkada retweetledi
Kesavardan S
Kesavardan S@keshu_VRimmCh·
Our recent work: Identified #viralRHIMs in RNA viruses originated from #bats, including SARS-CoV-2. Viral RHIM in SARS-CoV-2 #Nsp13 shows distinct cell death regulation in bat and human cells. Also, associated with Z-RNA sensing and #ZBP1-RIPK3 signaling.
Sanchita Mishra@SanchitaMishr20

Elated to share our work reporting functional #viralRHIMs in bat-RNA viruses and their regulation of ZBP1-RIPK3-associated cell death, now out on @iScience_CP. Huge thanks to @keshu_VRimmCh for guidance,@Disha__dak,#Ayushi for their efforts.@CellPressNews cell.com/iscience/fullt…

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avinash karkada retweetledi
Kesavardan S
Kesavardan S@keshu_VRimmCh·
New work: Decoding non-human mammalian adaptive signatures of 2.3.4.4b #H5N1 to assess its human adaptive potential. We aim to understand the non-human mammal adaptations of panzootic 2.3.4.4b H5N1 and assess the human adaptive potential of 2.3.4.4b H5N1 biorxiv.org/content/10.110…
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avinash karkada retweetledi
Kesavardan S
Kesavardan S@keshu_VRimmCh·
New work: Decoding non-human mammalian adaptive signatures of 2.3.4.4b #H5N1 to assess its human adaptive potential. We aim to understand the non-human mammal adaptations of panzootic 2.3.4.4b H5N1 and assess the human adaptive potential of 2.3.4.4b H5N1 biorxiv.org/content/10.110…
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Kesavardan S
Kesavardan S@keshu_VRimmCh·
A Green and Bright Day at @iiscbangalore Our lab picture at IISc.!! Our group is interested in investigating the Emergence of Pandemic viruses, Reservoir host Biology, Z-RNA sensing and Cell Death. @BICS_IISc
Kesavardan S tweet media
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avinash karkada retweetledi
Kesavardan S
Kesavardan S@keshu_VRimmCh·
This discussion might need few more facts to considers. First, the 2.3.4.4b H5N1 is a novel strain. Got new changes on surface proteins (HA and NA). H5 HA shows 6 or 7 glycosylation site (GLS) patterns unlike previous strains having 8-9 GLS. nature.com/articles/d4158….
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Sanchita Mishra
Sanchita Mishra@SanchitaMishr20·
2.3.4.4b #H5N1 has been spreading rapidly & infected several #mammal species, including #cattle. This work reveals molecular virologic factors leading to 2.3.4.4b H5N1 emergence & a new molecular program deciding avian flu HA & NA pairing. @iiscbangalore
Kesavardan S@keshu_VRimmCh

Our new work attempting 2 important questions: Why did 2.3.4.4b clade #H5N1 emerge as a highly pathogenic panzootic virus, which has not been achieved by previous viruses? Is the pairing of avian influenza HA and NA stochastic or molecularly programmed? biorxiv.org/content/10.110…

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avinash karkada retweetledi
Kesavardan S
Kesavardan S@keshu_VRimmCh·
Avian influenza virus neuraminidase stalk length and haemagglutinin glycosylation patterns reveal molecularly directed reassortment promoting the emergence of highly pathogenic clade 2.3.4.4b A (H5N1) viruses biorxiv.org/content/10.110…
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avinash karkada retweetledi
Emmanuel
Emmanuel@ejustin46·
𝙃𝙤𝙬 𝙢𝙤𝙡𝙚𝙘𝙪𝙡𝙖𝙧 𝙛𝙖𝙘𝙩𝙤𝙧𝙨 𝙜𝙤𝙫𝙚𝙧𝙣𝙞𝙣𝙜 𝙬𝙝𝙞𝙘𝙝 𝙃𝘼-𝙉𝘼 𝙘𝙤𝙢𝙗𝙞𝙣𝙖𝙩𝙞𝙤𝙣𝙨 𝙙𝙤𝙢𝙞𝙣𝙖𝙩𝙚 𝙙𝙧𝙤𝙫𝙚 2.3.4.4𝙗 𝙃5𝙉1'𝙨 𝙪𝙣𝙥𝙧𝙚𝙘𝙚𝙙𝙚𝙣𝙩𝙚𝙙 𝙨𝙥𝙧𝙚𝙖𝙙 ? 𝘎𝘳𝘦𝘢𝘵 𝘫𝘰𝘣 𝘰𝘧 @keshu_VRimmCh H/t @siamosolocani biorxiv.org/content/10.110…
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Keşfet

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