Cesar Bautista Sotelo

New preprint from @ScotWolfe1's lab. We address two different bottlenecks of #primeediting (solubility of the PE protein & dNTP concentration in the cell) by rationally engineering new prime editor variants. biorxiv.org/content/10.110…

Congratulations Job Dekker of @UMassChan, newly inducted NAS International Member! #NAS160 #NASmember #genetics #molecularbiology

Congratulations to @TianxiongYu and @ZhipingWeng on a beautiful paper exploring what drives transposon insertion in Drosophila! academic.oup.com/nar/advance-ar…

MD/PhD student Tomás Rodríguez restarted @UMassChan’s Latino Medical Student Association chapter in 2020. He established the optional Medical Spanish elective in collaboration with students from all three schools. #HispanicHeritageMonth @trodriguezUMMS @UMassMDPhD @UMassChanSOM

In case you missed this point, It’s all about the gaps for therapy response!

Calling on all conference organizers and professional scientific societies - please do not organize conferences in states that restrict women’s rights. I will certainly not attend and I urge other scientists to not attend. Yes, I know there are also good people in these states 1/

The field of genomics requires deep mental flexibility to solve some of biology’s most challenging questions. A diverse, inclusive genomics workforce is critical so that we gain different perspectives and experiences.

How we came to use agar for bacterial plates 😱

Sarah Cleveland & Judy Huang, diversity and inclusion co-chairs for the Graduate Student Body Council and active participants in @DIGGSBS, are the winners of the second Student Justice, Equity, Diversity, Inclusion (JEDI) Leadership Award. @Sarahb_clev @judyqyhuang @UMassChanGSBS

My first author paper is out in @Dev_Cell !! We suggest an important functional role for gamma secretase in synapse maturation, many thanks to @drosophilosophy and all of @MoscaLab for their incredible efforts! cell.com/developmental-…

I am distinguishably honored to announce that I will be joining @Columbia University as the Endowed Herbert and Florence Irving Assistant Professor of Physiology & Cellular Biophysics, and Dermatology, affiliated with Biomedical Engineering @ColumbiaBME, this fall.

Excited to announce that today is my first day as an Assistant Professor @UMassChan in @UmassMedbioinfo and @RTI_UMassChan. The Moore Lab is officially open! moore-lab.org 1/4

I'm thrilled to share our MuSiCal (Mutational Signature Calculator) manuscript: biorxiv.org/content/10.110… Mutational signature analysis, pioneered by colleagues at Sanger, has become a key tool for interpreting somatic mutations identified in sequencing data. 3 main concepts (1/8):

New dog paper! #tweetorials from first author @morrilleen and me on way as soon as we figure out how to distill 8 years of work into 280 chars. HUGE thanks to 18K+ dogs & owners @UMassChan @broadinstitute @karlssonlab @darwinsarkfnd #ScienceResearch science.org/doi/10.1126/sc…

This is really cool unexpected mechanism to cause chromothripsis ! nature.com/articles/s4158…

@nyugrossman logic: “47 individuals were not affected so it all must be okay”

Melissa’s Ted talk ted.com/talks/melissa_…

If I’m faculty at NYU, I’m looking at the female trainees in my lab and at my female colleagues and realizing my institute doesn’t care about them, and I’m considering my exit strategy.

@OliviakUmana @nyugrossman “It’s okay women, look past your trauma , you’re being hysterical, he is doing the ~science~” @nyugrossman

Speaks highly of the culture at @nyugrossman. Their statement was heard, “We welcome sexual assault at our institution”

Pangolin: Predicting RNA splicing from DNA sequence genomebiology.biomedcentral.com/articles/10.11…