Bede Constantinides (@beconsta) - Twitter Profili

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Preprint: How best to remove human reads from microbial FASTQs? Our tool Hostile removed >99.6% of human reads while retaining >99.997% and 100% of simulated reads in bacterial and mycobacterial metagenomes biorxiv.org/content/10.110…

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Bede Constantinides@beconsta·21 Ara

@microbiome_cosi Hello, are you able to point me to a working download URL for the CAMI 2 "Multisample Benchmark Dataset of Human Microbiome Project"? This page currently returns an error: repository.publisso.de/resource/frl:6… Thanks!

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Microbiology Society@MicrobioSoc·16 Eyl

Check out our latest blog from Dr. Inês Mendes and Dr. Bryan A. Wee, members of the Public Health Alliance for Genomic Epidemiology @pha4ge . They show how ‘bad data’ can be made more valuable by tagging them with information about their potential issues. microb.io/3Xrg9kH

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Tuuli Lappalainen@tuuliel·10 Eyl

Air purifiers in Finnish daycare reduced children's illnesses by 18% in a carefully controlled study. This implies huge potential for better public health and cost savings from sick leaves, with a simple intervention against airborne infections. yle.fi/a/74-20089670

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Zamin Iqbal@ZaminIqbal·1 Eyl

Great pleasure to work with @shenwei356 on a new indexing and alignment scheme, called LexicMap: biorxiv.org/content/10.110… We have been working on uniformly reassembling, QC-ing and annotating all bacterial (+ now archaeal) data, & wanted to be able to do full alignment to it....

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Robert Aboukhalil@RobAboukhalil·29 Ağu

I find it really interesting that biotechs & institutes often build their own bioinformatics workflow managers: - Insitro: Redun - GRAIL: Reflow - 10X Genomics: Martian - Invitae: in-house engine - CZI: Swipe - Broad: Cromwell - UCSC: Toil What does the future look like?

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Bede Constantinides@beconsta·31 Ağu

@AndrewxMontague @BadlyParkedOx Another way of looking at this is that the difference between the parking fee and fixed penalty (£40 if paid in the first 14 days?) should increase. A lot.

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Andrew Montague@AndrewxMontague·31 Ağu

@BadlyParkedOx I agree the car should not be there. OCC brings it upon itself though with stupid parking charges. Parks Road costs £18 for 3 hours (the only other option is 1 hour). Park & Ride is fine in many cases but for a recent visit with my grandchildren it would not possibly have worked

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Badly Parked Oxford@BadlyParkedOx·31 Ağu

Driver: Shall we visit University Parks? Passenger: Okay, shall we Park & Ride Driver: No, there's some fantastically wide pavements right by the main gate. Passenger: aren't pavements for people, not cars?! Driver: ... Parks Road

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Theo Sanderson@theosanderson·27 Ağu

Incredibly excited for the launch of Pathoplexus, which I've spent quite a bit of time helping with over the past year. New, open-source, infrastructure for sharing viral sequence data!

Pathoplexus@pathoplexus

📢 We're excited to introduce Pathoplexus, a specialized sequence database for human viral pathogens! 🌍 🧬 Launching with 4 viruses, Pathoplexus.org combines modern open-source software with transparent governance to improve global pathogen sequence sharing. 1/14

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Pathoplexus@pathoplexus·27 Ağu

📢 We're excited to introduce Pathoplexus, a specialized sequence database for human viral pathogens! 🌍 🧬 Launching with 4 viruses, Pathoplexus.org combines modern open-source software with transparent governance to improve global pathogen sequence sharing. 1/14

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Bede Constantinides@beconsta·23 Ağu

@ScouseMicrobe Congrats! Hear so many good things about this course

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Dr Justine Rudkin@ScouseMicrobe·23 Ağu

Even PIs like a certificate ⭐ After a week long course, I'm now a fully fledged Bioinformatician (aka, I know how to Google and use chatGTP for fix my code).

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Bede Constantinides@beconsta·22 Ağu

@AOUBIO @nanopore @Udahemuka1 @1986Bom @MarionKoopmans Hi Anton, excellent news. Matthijs has shared a BED file for this scheme, which I have adapted and made available here in the @pha4ge primer-schemes repository: github.com/pha4ge/primer-…

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Anton🔬@AOUBIO·19 Ağu

MPOX update: Our @nanopore sequencing protocol/primers for #MPOX clade IIB also work for clade IB. As this is confirmed by work performed in DRC using these primer sets by @Udahemuka1 @1986Bom @MarionKoopmans Publication Eurosurveillance: eurosurveillance.org/content/10.280… 1/2

Anton🔬@AOUBIO

Together with @amsterdamumc @Flahless1 @viroloog we developed a PCR tiling method for #Monkeypox using @nanopore. Method is tested on 40 monkeypox samples in a 42 minute #NextGenPCR program. This method is inspired by Midnight, @freed_nikki and @NetworkArtic 🧵 First data⬇️

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Lucy Taylor@LucyT_journo·20 Ağu

Kicking off a new series of #TheLifeScientific today, @jimalkhalili talks to Microsoft founder @BillGates about science-driven philanthropy, the power of vaccines and having a sense of humour about conspiracy theories… from 9am @BBCRadio4 or @BBCSounds: bbc.co.uk/programmes/m00…

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Bede Constantinides@beconsta·12 Ağu

@simoninthelakes @sam_bidwell It is either sloppy journalism or more likely intentional deception given that @sam_bidwell works for a notorious dark money funded, pro-eugenics, Trussite think tank (@ASI), in between stirring up hate with his Telegraph columns.

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Simon White@simoninthelakes·12 Ağu

@beconsta @sam_bidwell It was just a quip.

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Bede Constantinides@beconsta·12 Ağu

@simoninthelakes @sam_bidwell Which is true yet denied by Sam's first tweet. Clearly more doctors must be trained – this is a banal observation with cross party support for years already. However the Tories didn't actually want to pay for it, whereas this gov might. amp.theguardian.com/society/2024/f…

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Simon White@simoninthelakes·12 Ağu

@beconsta @sam_bidwell Nope. I was responding only to your comment that were the cap raised today we wouldn’t see the results for ~20 years.

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Bede Constantinides@beconsta·12 Ağu

@Richard07679148 @sam_bidwell I did read this. Given relatively low pay and poor working conditions in the NHS, recruiting overseas doctors without the prospect of UK settlement (a big carrot) would be a lot more challenging.

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Bede Constantinides@beconsta·11 Ağu

@NAccount86386 @sam_bidwell This assumes that HCWs would still want to come to the UK without the prospect of settlement. Many UK doctors already leave for better pay and working conditions abroad.

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AAKK@NAccount86386·10 Ağu

@beconsta @sam_bidwell x.com/sam_bidwell/st…

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Bede Constantinides@beconsta·11 Ağu

@GrumpyOldMan23 @sam_bidwell twitter.com/beconsta/statu…

Bede Constantinides@beconsta

@Mat_Oglesby @sam_bidwell Not at all. Sam's first tweet is demonstrably false and misleads the majority who read no further. Almost everybody agrees that we should train more doctors – it is stating the bleeding obvious. The question is how we create political appetite for such long term investment.

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David Smith@GrumpyOldMan23·10 Ağu

@beconsta @sam_bidwell Way to show you haven't read the whole thread. 🤡

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Bede Constantinides@beconsta·11 Ağu

@Richard07679148 @sam_bidwell twitter.com/beconsta/statu…

Bede Constantinides@beconsta

@Mat_Oglesby @sam_bidwell Not at all. Sam's first tweet is demonstrably false and misleads the majority who read no further. Almost everybody agrees that we should train more doctors – it is stating the bleeding obvious. The question is how we create political appetite for such long term investment.

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Bede Constantinides@beconsta·11 Ağu

@Mat_Oglesby @sam_bidwell Not at all. Sam's first tweet is demonstrably false and misleads the majority who read no further. Almost everybody agrees that we should train more doctors – it is stating the bleeding obvious. The question is how we create political appetite for such long term investment.

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Mat Oglesby@Mat_Oglesby·11 Ağu

@beconsta @sam_bidwell The point has flown entirely over your head. He offers a very sensible proposal for this problem at the end of the thread.

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Bede Constantinides@beconsta·11 Ağu

@Angie_Marie_1 @sam_bidwell The system has finite capacity to train new HCWs, making caps practically necessary. But these should be increased sustainably year on year.

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Angel A@Angie_Marie_1·11 Ağu

@beconsta @sam_bidwell If the cap had never been in place to start with, we'd have had home grown doctors graduating every year.

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Bede Constantinides@beconsta·11 Ağu

@TeaNoSugar1987 @YRespectfullyK @sam_bidwell Of course – Sam's first tweet is demonstrably false and misleads the majority who read no further. Almost everybody agrees that we should train more doctors – it is stating the obvious. The question is how we create political appetite for such long term investment.

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Rightly So@TeaNoSugar1987·10 Ağu

@beconsta @YRespectfullyK @sam_bidwell Did you read the whole thread?

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