Bijan Salehizadeh

Ok this clip about navigating the American Healthcare System from the recent South Park ozempic special (which was brilliant) needs to be the opening of every healthcare conference panel

Steeze Burger day 1. Love to see a great food truck (and best burger in DMV) open a shop. steezeburgers.com

@Biohazard3737 Cynicism has been right every step of the way last 3 mos

@DrJesseMorse @ChrisCuomo Rich and famous medical care is often worse than regular care. Corners are cut. Sad.

“NASCAR driver Kyle Busch died from severe pneumonia that progressed into sepsis,” according to a statement provided by the Busch family on Saturday. This is what I speculated likely happened yesterday and discussed last night with @ChrisCuomo. This was a totally preventable situation. Hindsight is 2020, but ideally when he was calling for help and a “shot” from his doctor two weeks ago. The proper protocol would’ve been to have him admitted to the hospital and get IV antibiotics with proper monitoring. Based on what we have heard, this was not the case, and his medical team allowed him to maintain his strenuous activities despite this ongoing infection that eventually evolved into pneumonia. The fact that he won a race less then a week before he passed away, meaning that he was still actively dealing with this infection, is nothing short of extraordinary. It shows you how good of shape he was in and also the power of the mind. Unfortunately, his powerful mind ended up being a double-edged sword, preventing him from getting the proper care he deserved, which unfortunately led to his shocking passing. "The medical evaluation provided to the Busch Family concluded that severe pneumonia progressed into sepsis, resulting in rapid and overwhelming associated complications," the Busch family statement read. "The Family asks for continued understanding and privacy during this difficult time." Busch died Thursday at age 41. May he Rest in Peace.

@slotkinjr @IterIntellectus I can’t wait

@IterIntellectus If the broadcast looks anything like this it’s gonna kill

man, i'm so excited for this

Rob Base, one-half of Rob Base & DJ E-Z Rock, who was best known for the hit “It Takes Two,” has died at 59 from cancer. “Rob’s music, energy, and legacy helped shape a generation and brought joy to millions around the world. Beyond the stage, he was a loving father, family man, friend, and creative force whose impact will never be forgotten,” reads a statement on his social media account. “Thank you for the music, the memories, and the moments that became the soundtrack to our lives.” variety.com/2026/music/new…

.@ManOnThePen estimates that well over 1m people have tried reasearch grade retatrutide. That seems quite plausible to me.

@DrJesseMorse Aortic dissection?

Kyle Busch - 911 call He reportedly passed out while in his racing simulator at home. He was struggling to breathe, overheating and coughing up blood. The coughing up blood has me concerned for a blood clot. Could be multiple reasons including the current infection, history of trauma to his leg a couple months ago and other factors (infections, vaccines) to name a few. There’s a chance the sinus infection became pneumonia, which could have led to sepsis. A blood clot in his lung could have led to perfusion issues or even caused a heart attack (saddle embolus). x.com/TMZ_Sports/sta…

@lawliepop Or the whole thing is a weird lie. It’s just all so odd.

Okay how many people think Sam messed up or the compounding pharmacy messed up?

Obesity fuels many cancers & serious disease. In direct contrast to the misguided and stupidly dangerous 'fat acceptance movement', new studies show GLP-1s are linked to slower cancer progression & better survival. Observational data only, so more research required. Obesity is a disease but now an entirely reversible one with modern medicine.

Replacement fertility in one chart: Even if 90% of women have children and average 2.2 each, we still fall short. Why? The fertility rate of a population equals the product of the proportion of women who have children and the average number of children per mother. That is, if 90% of women have children and the average number of children per mother is 2.2, the fertility rate of this population is 1.98. This simple formula gives us the relationship between the proportion of mothers in a population and the average number of children per mother required to reach the replacement rate. As I explained two days ago (check my feed if you missed it), this replacement rate is 2.1 in Western countries, where sex selection and infant mortality are low. The figure plots the result (if you are technical, this is called the iso-replacement curve). Obviously, if 100% of women become mothers, the average number of children per mother required to reach replacement is 2.1. If we move to 90%, this average rises to 2.33. Notice that if we fall to 80%, the average increases substantially to 2.6. I selected 80% because it implies that one in five women never becomes a mother, close to what we now see in Japan and parts of Southern Europe. The current young cohorts in advanced economies seem to be on track to be well below 80%, but we will not know for sure for another 20 years or so. Having an average of 2.6 children per mother requires many very large families. And modern societies are not organized for this to happen.

NEW exclusive - HHS has found a new lever (using existing law + AI) to cut off potentially billions in funding it believes is wasteful Gift link wsj.com/politics/polic…

Now that we have phase-3 results for retatrutide, it's time to revisit the question: What would happen to obesity if we gave every obese (BMI 30+) person the drug for just one year? Well, the obesity rate would fall by more than 80%! We'd be skinnier than the U.S. circa 1980!

@rorynotsorry Totally agree. Great analysis. To me, far more interesting will be the RHR data from this and other studies to come. That too is titration speed and dose dependent based on P2 data.

Maximum Tolerated Dose All these Eli Lilly posts and the one thing missing is a clear indication that the protocol will be towards titration up to the Maximum Tolerated Dose (MTD)... in fact, the whole 104-week extension was designed toward this. For those naysayers who will rail against higher doses and losing weight too fast... look at the actual clinical timeline math. Even at the maximum 12mg dose, the average weight loss per week was only 0.88 lbs in the main phase and 0.82 lbs in the long-term extension. That is perfectly within the optimal medical recommended safety zone of 1 to 2 lbs per week—and nowhere near a dangerous crash-dieting pace. Why does real-world data contradict so many people on X who always talk about staying on the lowest dose forever? Because X is a bubble. It is not representative of the real target population of ordinary Americans who have severe obesity struggles (we are talking a starting trial BMI of 40.0 to 42.8). For them, low doses miss out on the massive metabolic and cardiovascular benefits unlocked at the top. In the 104-week extension period, the trial design structurally guaranteed that the drop-out rate was stable. Why? Because to even qualify for the extension, patients had to prove their tolerability by week 80. The 11.3% who couldn't handle the 12mg side effects dropped out early during the aggressive ramp-up phase, leaving a highly compliant group for the long haul. The question isn't whether the goal is maximum tolerated dose. The real question in the future will be titration schedules. Phase 2 data already proved that dropping the starting dose to 2mg and slowing down the escalation cuts GI side effects from 50% down to 13%. Slower titration schedules are the future to reducing drop-outs and getting real people to the MTD they actually need.

Incredible weight loss data from Retatrutide. At 4mg low dose, Reta is close to high dose Tirzepetide.

I need a beta blocker to watch these NBA games. Just incredible.

@ddiamond Just amazing. Some of the best playoff hoops I’ve ever seen. Such intensity.

there should be a TV channel that just streams Thunder-Spurs 24/7. These games have been incredible.

Jeff Bezos with straightforward simple logic. Bottom 50% pay no taxes + costs government 3%. Yet 100% life changing for this bottom half of America A smart and simple approach worth doing.

Who has a higher positive rating than AI? Trump Republicans Democrats ICE Who has lower positive rating than AI? Iran Everyone pitching AI to the public should be fired.

Scoop on the biggest venture returns EVER: Founders Fund and Valor set to make more than $60B gains on SpaceX IPO, Sequoia more than $20B theinformation.com/articles/space…