Bita Moghaddam بيتا مقدم

Truly an honor to give the NIH Director’s WALS lecture today especially as the last speaker under the leadership of @NIHDirector Dr Monica Bertagnolli

@CarlosEAlvare17 @zenbrainest ..the fact that Grin2a/NR2a reaches adult level expression in early adolescence and when positive symptoms emerge, hence why we wanted to see if KO of Grin2a in DA neurons is sufficient to produce psychosis relevant phenotypes

@CarlosEAlvare17 @zenbrainest Thank you. This was a multi year team effort because it involved age (adolescent) and cell (dopamine and GABA) specific KO of Grin2a followed by detailed and clinically relevant phenotyping. GRM3 etc are also critical targets but the interest in Grin2a and dopamine stem from...

Out today! A truly team effort and one of my favorite lab projects The data connect NMDA/Grin2A malfunction to dopamine dynamics and related behaviors, and provide a futuristic model to develop and test "course altering" treatments for schizophrenia nature.com/articles/s4138…

Today, May 12, we celebrate the birthday of Maryam Mirzakhani (1977–2017) - the first woman and first Iranian to win the Fields Medal. Her groundbreaking work on Riemann surfaces and moduli spaces continues to inspire mathematicians worldwide. May 12 is now International Women in Mathematics Day.

A reminder that the science behind Ozempic traces back to research on the saliva of the venomous Gila monster. The kind of strange, foundational research that would almost certainly have been cut under today’s standards.

@AndrewHires @Adityalch well-said @AndrewHires - wish the enhancement bros would spend time with people like my sharp and agile🙏 93 yo dad and his lot. All are thin but have been active all their lives, take no supplements, no issues with lipids or BP because they eat real food but not too much of it

@Adityalch The enhanced games are an interesting social experiment. Traction will really require society to drop the pretense that their heroes aren't already "cheating."

Myostatin inhibitors will be bigger than any GLP-1 I just analyzed results from 4 recent Phase 2+ trials: + Bimagrumab (Lilly) + Trevogrumab & Garetosmab (Regeneron) + Apitegromab (Scholar Rock) + Enobosarm (Veru) The results are insane We're entering the Era of Enhancement:

The synthetic biology community lost one of its founding giants today. @CraigVenter5 - scientist, provocateur, and relentless force of nature - has passed away. Craig didn't just study life. He decoded it, synthesized it, and dared to ask what it meant to create it from scratch. At a time when sequencing a single genome took years and billions of dollars, he built a private company, assembled a supercomputer, and raced the entire federal government on the Human Genome Project - finishing in a (somewhat orchestrated) dead heat, standing in the White House in June 2000 alongside President @BillClinton and Francis Collins. It was a moment that changed biology forever. But the genome race was only the beginning. In 2010, his team at @JCVenterInst achieved something that had never been done in the history of life on Earth: they booted a cell using an entirely synthetic chromosome. The field we now call synthetic biology - the field that @SynBioBeta was built to champion - owes an enormous debt to that breakthrough and to the audacity it took to attempt it. Craig was never content to stay in the lab. He sailed the world's oceans on Sorcerer II, cataloguing microbial diversity and discovering more new genes in a single expedition than science had documented in all prior history. He founded Celera Genomics, TIGR, JCVI, @humanlongevity, and Synthetic Genomics. He was named one of @TIME's 100 Most Influential People, awarded the National Medal of Science, and remained - until the end - constitutionally incapable of retiring. He once said: "If you want immortality, do something meaningful with your life." He did. Many times over. The SynBioBeta community would not exist without the world Craig Venter helped build. We are grateful for his science, his swagger, and his refusal to accept the limits others placed on what biology could do. He will be deeply missed. synbiobeta.com/read/a-synthet…

I especially love this because Norway is a top global oil producer and 90% of its electricity comes from hydro They use the oil income to fund incentives and programs. They may be the only major oil producing country that is not bogged down by corruption, poverty or oligarchs

The Persians freaking collected a toll from the Romans, lol. You go to war with these people and they are like 'let's see, what did we do 2,000 years ago in a similar situation?'

Folks, I stepped into a leadership position at @dgsomucla in a very challenging time for science funding. I’m developing new ways to support our community.

"In all of this emptiness — this is a whole bunch of nothing, this thing we call the universe — you have this oasis, this beautiful place that we get to exist together." – @AstroVicGlover #ArtemisII #EarthDay2026

Thank you Mo

این پست من را از استرالیا،افریقا، آسیایی شرقی، اروپا، امریکا جنوبی، مرکزی و شمالی لایک کردند و محترمانه کامنت گذاشتند. تنها تنها، گروهی که بی احترامی کردند،فحش مادر به من دادند و نژاد پرستی کردند طرفداران رضا پهلوی بودند.

So much for American marksmanship.

News: Dr. Jennifer DeVoe, a prominent national leader in family medicine, claimed in a lawsuit threat obtained under Oregon's public records law that her removal from a $200k-a-year job at @OHSUNews was driven by sexism and ego. @TheLundReport thelundreport.org/content/lawsui…

I fully condemn the hateful rhetoric, lies, cruel and deliberate misinformation, and threats that my family, my staff, and I have been subjected to since the Iran War began nearly 8 weeks ago. These coordinated attacks and threats have only continued to worsen, most recently after I introduced Articles of Impeachment against Pete Hegseth. This conduct has crossed the line into threats to our physical safety, which we have reported to law enforcement. Bad actors have tried to smear my family and staff by circulating fake and AI-generated images and flat-out lying that my parents and I are not U.S. citizens. They have pushed xenophobic and sexist attacks and amplified absurd conspiracy theories about my family. They’ve even gone so far as to spread the outright lie that I am somehow tied to the regime. I will say this once and move on: these absurd allegations are entirely false and I denounce them in the strongest terms. These attacks aren’t about truth; they’re the product of desperation from those trying to distract from a failing, illegal war, rising costs of living, and an administration with no coherent strategy while Americans pay the price at the pump. And while they spread lies, American service members are being put in harm’s way, with real casualties mounting in a war that lacks both justification and direction. Let me reiterate, once again, that I have been unequivocal in my opposition to the brutal Islamic Republic regime, its repression of women, and its support for terrorism. My record on this issue is longstanding and crystal clear. My family has personally experienced the regime’s brutality.  It is in part why I am who I am today: A proud American speaking out for human rights and democracy, the rule of law, and, as a U.S. Congresswoman, the safety and security of Americans. It is also why I know the costs of freedom and stand firm against Donald Trump and Pete Hegseth’s illegal war. As a public figure, I fully expect public criticism and wholly respect Americans' constitutional First Amendment rights to free speech. I understand the high emotions during such a tenuous time for those who have family in both Iran and the United States. But I will not tolerate direct threats levied against my loved ones and staff who did not sign up for the public spotlight. I also won’t be silent as they are targeted, doxxed, and attacked online. This has not been a good-faith policy debate. It is a coordinated effort to smear, intimidate, and silence, and it will not succeed.   My duty is clear: to uphold the Constitution of the United States and to faithfully serve the people of Arizona’s 3rd Congressional District. It is the honor of my life to represent the people of Arizona in Congress, over 75 percent of whom are deeply opposed to this war. I remain committed to doing so with integrity and transparency.

So @leslievosshall, how about if the @hhmi_science news team stopped focusing on papers in Nature, Science etc... and instead only linked to news stories about preprints?

Pete Hegseth quoted a fake Bible verse from Pulp Fiction during a Pentagon sermon.

NEW: Speaker Mike Johnson told reporters today that Pope Leo XIV doesn't understand “something called the just war doctrine.” Pope Leo is an Augustinian friar who spent twelve years leading Augustine’s religious order. Augustine invented the doctrine. thelettersfromleo.com/p/something-ca…

Move over psilocybin and ketamine: GLP-1 also cures everything (Gift article) nytimes.com/interactive/20… via @NYTOpinion