
BogunovicLab
806 posts

BogunovicLab
@BogunovicLab
Studying human immunogenetics to unveil new biological paradigms explaining susceptibility to infection and/or inflammation. #children #immune defects #genetic


1/ Spotlight on our former trainee Dusan Bogunovic (@BogunovicLab), a postdoctoral fellow in our NY lab from 2010-13 and now Professor of Pediatrics, Vice Chair for Basic Research, and Director of the Center for Genetic Errors of Immunity at @Columbia.

In this Perspective, Casanova @casanova_lab discusses the 30-year history and future implications of emerging science showing that monogenetic lesions, and #autoimmune disorders targeting the same components of host defense, can underlie the same infection hubs.la/Q048F5Zz0









Sazeides et al. @BogunovicLab show that human ISG15 deficiency is a monogenic syndrome that poises individuals to a proapoptotic and profibrotic state that can lead to lung and skin damage with scarring and impaired function via chronic inflammation. hubs.la/Q044Ds9W0














