Brian Smith Lab

Breaking News: A Feast of Genomics in 3D lead by Dr. Brian Smith, Co-Director, Structural Genomics Unit @MCW_Research @UDNconnect @RareDiseases @MCWPediatrics @MCWCancerCenter @Dr_R_Kurzrock

The Program in Chemical Biology is hiring a bachelor's or master's level chemist to join our highly collaborative team: careers.peopleclick.com/careerscp/clie…

#Smithmigas #womeninscience #WomenInSTEM #InternationalWomensDay

We're excited for our PBRM1 bromodomain inhibitor work to be featured in @PracticalFrag! A nice example of our @mcwchembio fragment screening pipeline. Thanks to @EmilyDykhuizen for cell work. @MedicalCollege @MCW_Research

New Smith Lab from @MedicalCollege of WI publication in @ACSBioMed Journal of Medicinal Chemistry: "Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening" doi.org/10.1021/acs.jm… #bromodomains #NMR #PBRM1 #SAR

The Program in Chemical Biology at the Medical College of Wisconsin has opened a search for tenure-track positions. Review of applications will start October 14. For more details visit our posting in C&E News:chemistryjobs.acs.org/job/37535/assi…

Hot off the press from the Smith Lab at @MedicalCollege of WI! "N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic ß-cells" tinyurl.com/2p9amwxh #bromodomains #p65 #BRD4 #diabetes

New publication from @Sprague_Dan of the Smith Lab - Trisubstituted Triazenes : the First Ligands of the sY12-Binding Pocket on Chemokine CXCL12 in @ACSMedChemLett pubs.acs.org/doi/full/10.10…

Felice was the recipient of our 10,000th COVID-19 vaccine administered by medical student Natalie Yass. Learn more about the COVID-19 vaccines here: covid19.mcw.edu #ThisIsOurShot

Wearing a mask helps reduce the spread of COVID-19 when used in conjunction with other preventative measures, including physical distancing, frequent hand washing and cleaning high traffic surfaces. #WearAMask

@Sprague_Dan You've got this!

Does applying to residency tomorrow terrify anyone else? No, just me? Okay. Carry on!

Cheers to the #TwoWomen scientists who won the #NobelPrize in chemistry today! Congrats @doudna_lab and Dr. Charpentier!

Signal boost nejm.org/doi/full/10.10…

New Smith Lab publication in Bio-Organic Chemistry - Novel activity-based probes targeting #sirt1, inspired by Cravatt lab #HDAC probes. Inaugural 1st-author paper for @mcwgradschool student @cjgoetz; teamwork by @Sprague_Dan. authors.elsevier.com/a/1biMOAHs8Ts2…

Why has no one thought of opening a bar near a hospital and calling it PubMed

Excited to share that Dr. Robert Golden, Dean of @uwsmph and I crafted an op-ed in the Milwaukee Journal Sentinel on the @AAMCtoday road map to reset the nation's approach to the COVID-19 pandemic. This important message should be shared far and wide! jsonline.com/story/news/sol…

Congratulations to our newest #NIH T32 postdoctoral trainees, Ryan Adam, PhD, Joshua Nord, PhD, and Michael Flinn, PhD @ivorbenjamin2 facebook.com/Cardiovascular…

This is not a new idea, but it bears repeating. "All lives matter" is a worthless phrase until black lives are also included in the "all". #BlackLivesMatter

“The new study does not ask why, but earlier research, including an analysis published last year by the NIH, has found that black applicants are more likely to propose studying health disparities, which are less likely to be funded by the agency.” chronicle.com/article/Black-…

MYTH: Warm weather and heat can kill COVID-19. With all the information available about #coronavirus (COVID-19), it's important to separate fact from fiction. For trusted information and resources, visit the MCW Coronavirus Resource Center at: covid19.mcw.edu #MCWCOVID19