Brian Balgobind

@toddscarbrough I believe it could be indeed a new treatment field, first data are there. sciencedirect.com/science/articl…

@bvbal79 Could be brain dose of 5 to 10 cGy in certain settings. And over 30 fractions that adds up and COULD plausibly have an effect. I stress could. These are CT scan (or maybe more) similar doses, and CT scanning has been associated with Alzheimer improvement pmc.ncbi.nlm.nih.gov/articles/PMC48…

People of #radonc Please, please, please formally explore LDRT for #AlzheimersDisease Provocatively, please explore LDRT prophylaxis for Alzheimers based on genetic risk Thank you for your attention to this matter neurologyadvisor.com/news/breast-ca…

@ProfAJChalmers FU is short and there is no sham treatment involved to compare. Until now we still have to perform the correct study to prove radiotherapy is here to stay pubmed.ncbi.nlm.nih.gov/30366945/

@DoctorPhillEP @DrLPedersen @Alicardsdoc @carmenbergom this will be a shock in #Radonc world if true (new therapy)!

@NiuSanford never thought we would investigate this in 2023....

@NiuSanford abstract: patients receiving radiotherapy (RT) during “dark” season (fall/winter) may have better outcomes than those treated during ”light” season (spring/summer), possibly secondary to seasonal variations in cell cycle progression

Well, phew! If this were positive, I might have to consider moving back to Boston for the 8 months per year of winter/darkness.

@DrewMoghanaki @Mat_Guc @PBlanchardMD i think it will be still hard to contour cardiac substructures. We recently published a suggested update on the Feng paper including 3D-contouring based on contrast enhanced CTs. sciencedirect.com/science/articl…

Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT. #radonc ncbi.nlm.nih.gov/pmc/articles/P…

@EvanThomas84 @VarianMedSys @OSUCCC_James @OSUWexMed @the_RSS @ASTRO_org @DrewMoghanaki @_ShankarSiva @UABradonc @ParikhSimul @SprakerMDPhD @DrSpratticus Incredible! Waiting eagrly for your results. Radiotherapy goes beyond cancer these days

I'm incredibly excited to announce opening of our new sham-controlled RCT of #radiosurgery for #spasticity in patients with #spinalcordinjury, #CerebralPalsy, #stroke. Thanks to @VarianMedSys for funding & to my colleague & tx inventor, Dr Pantaleo Romanelli #Neurosurgery #pmr

@DrSpratticus @NicholasZaorsky @UHhospitals @joostverhoeff 😉

@NicholasZaorsky @UHhospitals Too kind Nick. It’s no big deal. I am just one of the team members just like you. All contributing in our own way. Also, hard to lead when you don’t know what the team is truly going through. No one likes the feeling of a disconnected “suit” dictating orders

Leadership by example: After starting as the new #radonc chair at @UHhospitals in 2021, @DrSpratticus made a "doc of the day" / call system for the department and put himself as the doc of the day every Friday PM. He also takes call, including holidays.

@DrewMoghanaki @aleberlin2 @alison_tree @nickva1 aim a linac at a target 🤣🤣🤣🤣

Conventional 1.8-2.0 Gy per day is reasonable for those who only know how to design an APPA or 4-field box, or don’t know how to properly aim a linac at a target. @aleberlin2 @alison_tree @nickva1

@drmattmc nah...radiation is dangerous

@toddscarbrough @SprakerMDPhD @LindsayPhys @SbrtSean i do think this could be right. Varian put all there money on ETHOS and hypersight. Perhaps Elekta can buy it to use the rights as mentioned on their own Unity. Time will tell what will happen, bad day for #radonc anyway.

@SprakerMDPhD @LindsayPhys @SbrtSean

ViewRay Bankrupcy: Who Will Buy It?

@toddscarbrough @SbrtSean 🤣🤣🤣

@NiuSanford we did a higher dose trail for inoperabel in the Netherlands,. pubmed.ncbi.nlm.nih.gov/34101496/

Why isn't organ preservation more of a thing for esophagus cancers (other than upper SCC)? In CROSS, pCR was 49% for SCC, 23% adeno - and that was with 41.4 Gy. With higher dose of RT, addition of IO, and longer interval to assessment, we could probably improve upon complete response rates - close to what we can get in rectal cancer. At what pCR rate should we be entertaining idea of organ preservation in GI tract cancers?

@ProtonStorey @NiuSanford that could be random not casual relationship.

@NiuSanford Ironically though, I looked at over 10k deliveries with ICDs and 2 devices needed to be re-programmed. Both were in prostate cancers so not bad to consider effects far from field.

I get the study is comparing IMRT vs. 3D radiotherapy for prostate cancer, but perhaps should at least mention baseline rate of new solid malignancies at 10 years in men >65 years without any RT to put into context. My guess is it’s also around 7%. jamanetwork.com/journals/jamao…

Sarcomen Team Amsterdam UMC (STA) voor patiënten en zorgverleners! sarcomenteam.nl

@toddscarbrough its a gray area i think

If you write “Gray,” I will hit you the force of five newtons. Maybe while eating Fig Newtons.

You know we don’t capitalize the radiation absorbed dose unit “gray” used in #radonc … right?

@NiuSanford Hills have eyes, movie with mutants due to radiation piosoning, i think se looks mutated😉

I’m missing the rad onc reference, but I do love Doja Cat 🐱!

@SprakerMDPhD @NiuSanford @toddscarbrough @KrishanJethwa @nbn426 long term there was evidence for OS

@SprakerMDPhD @NiuSanford @toddscarbrough @KrishanJethwa @nbn426 pubmed.ncbi.nlm.nih.gov/35084987/

Role of Radiation Therapy for Borderline Resectable Pancreas Cancer For (Joe Herman) hmpgloballearningnetwork.com/site/onc/video… Against (Lisa Kachnic)... "There seems to be no evidence to support my actual practice"(!!!) hmpgloballearningnetwork.com/site/onc/video…