CLabenz

We are pleased to announce that registration for ISHEN2025 is now open! ishen.org/ishen-2025/reg… We are accepting late breaking abstracts ishen.org/ishen-2025/abs… NOTE: There is very limited space. Registration will be open until full capacity 👉 Register today!

🚨 #GIHepFellowshipBootcamp is heating up with these 🔥 📑s on #HepaticEncephalopathy 🧠 ⭐️ Testing for CHE‼️ ⭐️ Risk factors for OHE‼️ ⭐️ Preventing OHE‼️ ⭐️ ⭐️ Treating HE ‼️ 💊 💩 journals.lww.com/hepcomm/fullte… journals.lww.com/hepcomm/fullte…

📄 Full paper: journal-of-hepatology.eu/action/showPdf… 📚 Related paper challenging the 24h albumin new rule: pubmed.ncbi.nlm.nih.gov/40250764/ #EASL2025

💉 Albumin duration & AKI response in cirrhosis Eva M. Schleicher (Mainz) – #EASL2025 🕒 24h albumin new rule questioned 🏆 EASL AKI response definition wins 📈 20% of 24h NR improved at 48h ⚖️ Early vs late responders: Same mortality 🚨 Cr ↑ >16% @24h → terlipressin! 👇

Today’s #readoftheweek📚discusses QuickStroop, which is a rapid screening tool to identify patients at risk for PHES-MHE, especially in patients below 60 years of age. Read here this @JHEP_Reports article: jhep-reports.eu/article/S2589-… 🙏@c_labenz @SJGairing @kaps_leonard @EvSchleicher @Maria_M_Gabriel @HeinerWedemeyer @b_maasoumy et al. #LiverTwitter #LiverX

❗QuickStroop for screening for minimal hepatic encephalopathy in patients with #cirrhosis 🔓#OpenAccess at 👉jhep-reports.eu/article/S2589-… #LiverTwitter

@ebtapper Same here!

Most fun I ever had writing …

Non-Invasive CSPH Estimated Risk (NICER) model including @Echosens SSM by VCTE at 100Hz 👉Developed (2020-2022) & validated (2023) in contemporary pts. 👉Outperforms ANTICIPATE(-NASH): AUC consistently >0.9. 👉Well-calibrated. 👉Sets a new standard IMHO. #LiverTwitter 🔗👇

Thrilled to have this work out in @HEP_Journal ! Short version: The problem - it’s hard to diagnose minimal HE or predict future overt HE in clinic What we found - automated speech analysis can do both

"No value of non-selective beta-blockers after TIPS-insertion" published 'open access' at bit.ly/3AF9rjs #livertwitter #TIPS

WHAT'S AT STEAK IN NUTRITION FOR HEPATIC ENCEPHALOPATHY? No one had more fun than me and @c_labenz writing this editorial: journals.lww.com/ctg/pages/arti… On @JasmohanBajaj trial of meat vs veg burgers and ammonia: journals.lww.com/ctg/fulltext/2…

Today @EASLnews, Martin Kabelitz presents his poster about the impact of #TIPS on frailty: 💪 Frailty has the potential to improve after TIPS insertion 🏋🏽 Especially patients with a high degree of frailty show improvement SAT-090 #EASL2024

@mathiasjachs & the Non-Invasive CSPH Estimated Risk (NICER) model based on a contemporary cohort integrating SSM-100Hz 👏 👉 Developed in SLD & 🦠 suppression/cure 👉 Improved discrimination & calibration. 👉 It's just the NICER model, I guess! 😜 Thanks @BavenoCoop!

Brilliant State of the Art talk by @dthabut on hepatic encephalopathy 🤩 Love that HE is getting this spotlight @EASLnews As the Professor stated: HE is the worst complication of cirrhosis We have a lot of work to do to improve this for our patients

1+ 1 = 3 Lactulose + Rifaximin = Reduced episodes of hepatic encephalopathy journals.lww.com/hepcomm/fullte… @HepCommJournal

There is no stepwise increase in the risk of encephalopathy with worsening psychometric scores in this international study journals.lww.com/hepcomm/fullte… @HepCommJournal @SJGairing @BloomPringle @c_labenz

🔑Are all proteins🟰 for ammoniagenesis? No! 🔑Can one meal change affect ⬇️#ammonia in #cirrhosis? Yes! ✅our #RCT where 1⃣ meal change from 🥩to 🌱/🌿-based was enough to⬇️#ammonia ! 🔑Impt because replacing full diets⛔️ 🔑metabolomic changes @ACG_CTG ⤵️ journals.lww.com/ctg/abstract/9…

🟪NEW Article in press❕ Proton pump inhibitor use and risk of hepatic encephalopathy: a multicenter study 🔓#OpenAccess at 👉jhep-reports.eu/article/S2589-… #LiverTwitter #HepaticEncephalopathy

Are you busy with #hepatology clinical work? Check out the clinical care points in this short and concise review on the cerebral effects of #cirrhosis and #portalhypertension from a group of @ISHENliver members. Out now in Clinics in #LiverDisease. 👇 authors.elsevier.com/a/1i-BM_OnBPgg…

Grateful for an amazing team effort! @SJGairing @MontagneseSara @BloomPringle @MMLauridsen @jumarquardt @ISHENliver @JHEP_Reports

Is PPI use associated with HE? Our multicenter study says no 🚫 ✅1160 patients with PHES at baseline 🚫no association between PPI use and MHE or OHE development 🚫>70% without an indication for a PPI prescription❗️ 👉read the study here: jhep-reports.eu/article/S2589-…