Cristhian Cañari Chumpitaz

Glad to share the artwork of our DNA supercoiling work now in the cover of @MolecularCell ! This cover was inspired in traditional Peruvian embroidery @peru 🇵🇪 to represent artistically our findings on apical localization of RNA polymerases on DNA plectonemes. #MarcaPerú #Peru

Excited to share our new preprint!🧬❄️ by brilliant Max Dreimann & Co! Using cryo-ET&EM, we reveal archaeal chromatin in a near-native state: variable-beads-on-a-string fibers shaped by growth phase and histone composition tinyurl.com/TkChrom

We thank @NatureSMB for the highlight on our Transcription/DNA supercoiling work. Transcription from supercoiled DNA | Nature Structural & Molecular Biology rdcu.be/fpcC2

You can find more on our work at Apical localization of RNA polymerases modulates transcription dynamics and supercoiling domains revealed by cryo-ET: Molecular Cell cell.com/molecular-cell…

Glad to share the artwork of our DNA supercoiling work now in the cover of @MolecularCell ! This cover was inspired in traditional Peruvian embroidery @peru 🇵🇪 to represent artistically our findings on apical localization of RNA polymerases on DNA plectonemes. #MarcaPerú #Peru

Finally out in @Cellcellpress! Proteins with long intrinsically disordered regions (IDRs) are prone to misfolding during protein synthesis. This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones. cell.com/cell/fulltext/…

Congrats to first co-authors Meng Zhang @Meng3054 and Cristhian Cañari-Chumpitaz @cccDNA for their DNA supercoiling work @BustamanteLab featured on the cover of @MolecularCell cell.com/issue/S1097-27… Highlight in @MolecularCell cell.com/molecular-cell… #Transcription #UCBerkeley

Excited to share that our @BustamanteLab work is featured on the cover of @MolecularCell cell.com/issue/S1097-27… Congrats to @Meng3054 and @cccDNA for their artwork and highlight in @MolecularCell cell.com/molecular-cell…

Our latest issue is now online: cell.com/molecular-cell…

Out now in Science! Our new study challenges long-standing assumptions about transcription factor specificity in eukaryotes. Novel single-molecule measurements of TF behavior in living cells reveal an independence of locus-specific binding from DNA sequence recognition.🧵 science.org/doi/10.1126/sc…

Nature research paper: Cellular water-potential sensing through biomolecular condensation go.nature.com/4e7IfuT

Everything you wanted to know about the protein chemistry behind how amino-acid changes affect the cellular abundance of proteins Effects of residue substitutions on the cellular abundance of proteins doi.org/10.7554/eLife.…

Spatial and genetic constraints govern transcription–translation coupling and mRNA degradation in bacteria dlvr.it/TSgFzG #MicroSky

Happy to share our new work published in @acsnano "Quantifying Photochemical Propulsion in Light-Powered Janus Micromotors". A collaboration among @BustamanteLab, Alivisatos lab and the Molecular Foundry pubs.acs.org/doi/10.1021/ac…

Rib-awesomes!

❤️ Team DNA Supercoiling!

Online Now: Apical localization of RNA polymerases modulates transcription dynamics and supercoiling domains revealed by cryo-ET dlvr.it/TSVTdL

Excited to share our new work published in @MolecularCell: “Apical localization of RNA polymerases modulates transcription dynamics and supercoiling domains revealed by cryo-ET”. We directly visualized transcription-induced DNA supercoiling domains in 3D! cell.com/molecular-cell…

Happy to share that our latest work at UC Berkeley is now published in @acsnano. A collaboration among @BustamanteLab, Alivisatos lab and the Molecular Foundry @molecularfndry. Quantifying Photochemical Propulsion in Light-Powered Janus Micromotors pubs.acs.org/doi/10.1021/ac…

We also observe that reducing rotational diffusion by functionalization with long DNA strands enhances the directionality and propulsion of these light-activated Janus particles.

In this work, we characterize the propulsion dynamics of light activated Au-TiO2 Janus particles and measure the forces generated during the propulsion events of their analogs Au-PS@TiO2 using optical tweezers.

Glad to have contributed to this work lead by my beloved @katy_requejo! A collaboration between the Bustamante and Alivisatos lab. Quantifying Photochemical Propulsion in Light-Powered Janus Micromotors | ACS Nano pubs.acs.org/doi/10.1021/ac…