Chris Zerio

32 posts

Chris Zerio banner
Chris Zerio

Chris Zerio

@chriszerio

Scientist

San Diego, CA Katılım Ağustos 2012
369 Takip Edilen260 Takipçiler
Chris Zerio
Chris Zerio@chriszerio·
Very excited to see my main postdoctoral research project peer-reviewed and published! We used cryoEM and biochemical experiments to uncover how Polymerase θ helicase facilitates DNA microhomology annealing to repair DNA in BRCA-deficient cancers. Paper: doi.org/10.1038/s41594…
Scripps Research@scrippsresearch

A DNA repair enzyme that some cancers rely on to survive could be the key to more precise treatments. The @LanderLab has captured the first images of Pol-theta in action, revealing how it repairs DNA—offering a blueprint for better cancer therapies. More: ow.ly/Y01T50Vf34V

English
0
0
9
424
Chris Zerio
Chris Zerio@chriszerio·
Thrilled to share my postdoctoral work in @Landerlab! The human Polymerase θ helicase undergoes conformational rearrangements to facilitate DNA microhomology annealing. These insights enable rational design of novel BRCA-deficient cancer therapeutics! tinyurl.com/jaddar9u
English
4
3
24
1.9K
Chris Zerio retweetledi
Lander Lab
Lander Lab@LanderLab·
Our first foray into the fascinating field of DNA repair! Congrats to postdoc Chris Zerio @chriszerio, who tested hundreds of oligos to identify one that trapped the helicase of human Polymerase θ in the process of annealing two strands of DNA. tinyurl.com/jaddar9u
English
7
30
160
18.3K
Chris Zerio retweetledi
Scripps Research
Scripps Research@scrippsresearch·
Scientists led by @LanderLab uncover a critical feature that a promising new class of #cancer drugs needs to be effective. These drugs need to cause specific shape changes in their target that can then trigger the breakdown of key cancer-driving proteins scripps.edu/news-and-event…
English
1
8
42
0
Chris Zerio retweetledi
May Khanna
May Khanna@may_khanna·
Fantastic talk by @ChrisZerio who is off to postdoc for @LanderLab in what is apparently the greatest EM lab 😊😊. He did a wonderful job with his talk, his acknowledgments were incredible. It was a treat!!!
May Khanna tweet media
English
0
1
8
0
Chris Zerio retweetledi
Puget Sound Baseball
Puget Sound Baseball@PS_baseball·
.@ChrisZerio had an incredible 4-yr career with the Loggers: 3x All-NWC selection and an All-West Region honoree. He has the second-best career BA in Logger history at .370. A stellar student Zerio is working on his PhD in Pharmaceutical Sciences at the Univ. of Arizona.#LoggerUP
Puget Sound Baseball tweet media
English
0
4
19
0
Chris Zerio
Chris Zerio@chriszerio·
Our baseball field is getting new stadium seating for this season! Thank you so much to the Cheney Foundation! bit.ly/1jmo4va
English
0
0
1
0

Keşfet

@kellogg_liz @LanderLab @CSHL @cshlcourses @hoelza @PS_baseball @elonmusk @BarackObama