ChubbyShark 🦈

Retatrutide phase 3 obesity trial just came out and the results are genuinely insane: - 28.3% bodyweight lost on 12mg over 80 weeks - 70.3 pounds on avg. or 31.9 kg - 45.3% of patients hit 30%+ weight loss (this is bariatric surgery territory) - 30.3% weight loss (85 lbs) at 104 weeks in higher-BMI patients - 65.3% of 12mg patients dropped below the obesity BMI threshold - 19% loss on 4mg over 80 weeks (47.2 lbs) with fewer dropouts than placebo (4.1% vs 4.9%) - significant drops in blood pressure, triglycerides, non-HDL cholesterol, waist circumference, and hsCRP - no cardiac or liver signals Retatrutide is going to completely overshadow tirzepatide and semaglutide, and take the throne as the best-selling drug of all time.

This 88 year old Japanese trader spent 40 years day trading and turned $387,000 into a $14 million portfolio. If he had simply bought the S&P 500 in 1986 and done nothing, he would have over $21 million today.

Stablecoin payment activity isn’t evenly distributed. Nearly two-thirds of the volume originates from Asia, primarily Singapore, Hong Kong, and Japan.

The Arbitrum Security Council has taken emergency action to freeze the 30,766 ETH being held in the address on Arbitrum One that is connected to the KelpDAO exploit. The Security Council acted with input from law enforcement as to the exploiter’s identity, and, at all times, weighed its commitment to the security and integrity of the Arbitrum community without impacting any Arbitrum users or applications. After significant technical diligence and deliberation, the Security Council identified and executed a technical approach to move funds to safety without affecting any other chain state or Arbitrum users. As of April 20 11:26pm ET the funds have been successfully transferred to an intermediary frozen wallet. They are no longer accessible to the address that originally held the funds, and can only be moved by further action by Arbitrum governance, which will be coordinated with relevant parties.

The EU Inc. will turn the promise & potential of the Single Market into a reality that businesses can truly rely on. A unified set of rules across the 🇪🇺 to make it easier to start, scale, succeed & stay in Europe. Some key takeaways from the open public consultation 👇

A perfect Friday in the Netherlands: 8:00 - Wake up 8:30 - Check portfolio. Down 10%. Pay 36% tax on unrealized gains 9:30 - Pick up wife from her boyfriend’s apartment 10:00 - Receive fine for cycling 2 km/h over the bike speed limit 10:30 - Start work 12:00 - Eat potatoes for lunch 14:00 - Write an angry LinkedIn post about Americans having no work-life balance 14:30 - Mandatory diversity seminar 15:30 - Finish work 17:00 - Apply for a permit to own a second bicycle 21:00 - Eat potatoes for dinner 21:30 - Read article about Europe having the highest quality of life 22:00 - Sleep on a couch because your wife’s boyfriend is staying over

For anyone wondering how a third-grader can complete six years' worth of math in a single year. This knowledge graph spans 3,000 math topics, from 4th grade to the university level, providing the perfect basis for mastery learning. Students can go as fast or far as they want! There are no restrictions whatsoever. The only requirement is that they must demonstrate mastery of each topic before moving on to the next. Kids are capable of incredible things when given that kind of freedom and support.

an all in one app with: - instant stablecoin payments - smooth IBAN <> crypto rails - a card that works everywhere - direct access to defi yields - self custody goes mainstream this year, 100%

BREAKING: Tether tumbles to $0.9980, its weakest peg in over 5 years. Some analysts warn a full untethering could hit soon, which could cripple the crypto market, as 87%+ of trading volume flows through USDT.

I think a lot about this picture I took of parents in a random Italian town at 10pm socializing with their kids in tow.