Christian Ieritano

Hey #TeamMassSpec @ScoHoDigDaSnow and I are proud to share our @PCCP perspective on what ions do inside a DMS/FAIMS cell. But don't panic, because this hitchhiker's guide to DMS translates the field into a language understandable by all academic levels. pubs.rsc.org/en/content/art…

Enjoying the beautiful science AND weather at @asmsnews Asilomar Conference on Ion Mobility-Mass Spectrometry. Download group pic here: asms.org/conferences/as… @J_ASMS #TeamMassSpec

@bljpoad @QUT @thermofisher Congratulations Berwyck! The gas phase ion chemistry and MS communities are going to miss you.

My time in academia will come to an end in two weeks. After 8+ years at @QUT, in September I will start a new journey as a Field Service Engineer with @thermofisher based in Brisbane. I'm incredibly excited!

@OldSchoolRS Plush ❤️

⭐FOLLOW & COMMENT TO WIN ⭐ 🐻 We’re giving away an iconic Gold Trimmed Rune Champion plushie! 📺 For more chances to win, save the date for this week’s livestream: Friday, May 17 @ 4PM BST This cuddly companion is on sale only until 23:59 on May 18: makeship.com/shop/runescape

Beyond excited for all the potential a North American FEL facility will bring to the #chemistry, #biology, #physics, and #TeamMassSpec communities

📢More exciting news for ion mobility enthusiasts! The MobCal-MPI manual has been updated with instructions of how to compile the source code on most platforms! We can't wait to all the exciting things #TeamMassSpec can do with MobCal-MPI 🙂 github.com/HopkinsLaborat…

Hey #TeamMassSpec, Have you heard? The MobCal-MPI 2.0 manual covers Fortran code installation! We promise it's less scary than deciphering my cat's plan for world domination. Plus, there's a tutorial on calculating CCSs from scratch - it's your time to be a CCS superstar💫

📢Exciting news for ion mobility enthusiasts! 💻MobCal-MPI v2.0 is out, offering accurate ion mobility and CCS calculations at any field strength with a user-friendly manual. Get it here: github.com/HopkinsLaborat…. Analyst publication (DOI:D3AN00545C) @cieritano @AHaack91

Congratulations to Dr. Ieritano, who successfully defended his PhD thesis in early August! We are looking forward to your continued contributions to the group and wish you the best of luck in your new permanent position on campus (more exciting announcements to come soon)!👨‍🔬

@ajtrev @uowresearch @MolHorizons And also gave a great talk on this topic at #ASMS2023 !

Boris’s careful study examines how protons change location with help from a methanol taxi ride - #masspec @uowresearch @MolHorizons pubs.acs.org/doi/10.1021/ja…

Hey #ASMS2023, do you enjoy beer, wacky separations? 🍻 If so, check out some posters featuring both of these topics today in the DMS/FAIMS session!

Looking for an alternative to those pen-and-paper exams for chemistry labs?🧑‍🔬 Carlee and Julie of @UWaterloo have cooked up a practical examination for undergrad synthesis labs - check out their work in @ACSDivCHED #ChemTwitter #AcademicTwitter pubs.acs.org/doi/abs/10.102…

@Nandoparticles @UWaterloo No you ♥️

@cieritano @UWaterloo You rock

And that's a wrap on thesis writing - just in time to celebrate at #ASMS2023! Thank you to all the #TeamMassSpec members and @UWaterloo friends who have made my PhD journey especially memorable.

@stshuken A wonderful addition to the #TeamMassSpec community!

‼️A guide to mass spec proteomics for beginners! Peer-reviewed and published AND OPEN ACCESS FOR THE NEXT SIX MONTHS! Answers to the questions: -How does MS proteomics work? -How do I perform a proteomic experiment? -Where can I learn more? #teammassspec pubs.acs.org/doi/10.1021/ac…

Hey #TeamMassSpec, want to learn about competing solvent modifiers for DMS/FAIMS? Check out this work in #JASMS, which explores this phenomenon and its applications for ion mobility! Congrats @justinebissonn on your first first-author publication! 🥳 pubs.acs.org/doi/10.1021/ja…

@inigo_iribarren The NEB method in ORCA is exactly what you are looking for :) orcasoftware.de/tutorials_orca… If you want more detailed info (ie. other possible intermediates), then its not really an interpolation, but more of a PES mapping. In that case, I'd recommend CREST xtb-docs.readthedocs.io/en/latest/cres…

Another time requiring help from the #compchem community! Has anyone done an interpolation of two conformations? Any suggestions on how to do it? I have seen the As-Rigid-As-Possible (ARAP) interpolation and it looks good to me. Any help is welcome! <3

@VRAdoesMS @StacyMalaker Very interesting. Do you happen the know the charge on some of these larger glycoproteins? Even with the extra "heating" that multiply charged ions will get during a FAIMS separation, I'm amazed that something so big still fragments! (apologies for all the questions)

@StacyMalaker @cieritano Yup! Looking at the analysis of depleted human serum from literature I see ~4500 Da peptides.

🚨Newest #glycotime #TeamMassSpec preprint from the Malaker lab! 🚨Here, @VRAdoesMS spearheaded a project where we evaluated the use of FAIMS for O-glycoproteomic analysis. What we found was quite interesting... 🧵👇doi.org/10.1101/2023.0…

@chrashwood @StacyMalaker The CV in which an analyte will transmit the DMS/FAIMS cell usually follows a Gaussian distribution with a FWHM of 2-5V, although it can be larger. Is it not more reasonable to say the analyte is being transmitted within the 45 - 55V CV window, and not transmitted at CV = 60V?

@chrashwood @StacyMalaker Dependence of survival yield on CV is rather strange - the CV offsets the "zero-point" of the FAIMS waveform. I can't find the SV used by the authors, but even at "lower" settings of say 2kV, CV increments of 10V won't cause the drastic changes shown in this figure.

@StacyMalaker @VRAdoesMS If you have any questions about this topic, please don't hesitate to reach out!

@cieritano Thanks for the citations, we'll definitely check them out! And this is a better question for @VRAdoesMS -- Val, see above. Also, note that we focused on O-glycopeptides which are smaller than N-glycopeptides (in length and glycan size), though I bet it's occurring there too