@ivanfioravanti I was experimenting with this same setup on my m4 max and it is incredible. Although at some point I did thought that claude code is beemttwr but this is definitely better than what we we're doing 6 months back.
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Kalpit Champanery
1.8K posts
Kalpit Champanery
@ckalpit
🚀 building @HealthKey_HK | Ex. Staff Engineer @ottimate_ap(aka Plate IQ) | @91mobiles | @pricebaba | Co-Founder at Digital Web Weaver | coder | enthusiast
ATX Katılım Eylül 2013
315 Takip Edilen387 Takipçiler
OpenCode + GLM-4.7-Flash 8bit.
llama-server vs mlx_lm.server.
Using one M3 Ultra for each host.
Same prompts, you can check duration for each step in the video.
Amazing experience on both side!
Local coding AI model are becoming reality! 🔥
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Kalpit Champanery retweetledi
15:45 Clinical Trials conversation is 🎯
#1 challenge with running trials is finding qualified patients.
@HealthKey_HK, we actually ran the Lp(a) study Dave @EliLillyandCo discussed at 16:35. We processed 10,000s of patients, and found 216 qualified patients from a single clinic in <24 hours.
This technology was impossible to build until last year, and we solved it.
John Collison@collision
Dave Ricks has been at @EliLillyandCo for 20% of its 150-year history. He came to the pub, poured his own Guinness, and gave us a 2-hour state of the pharma union: drug prices, clinical trials, patent clocks, the rise of generics, Chinese peptides, compounding pharmacies, the US healthcare system, and how the broad success of GLP-1s have transformed Lilly's business. If you've never heard Dave speak before, you're in for a treat. Timestamps: 00:00 Intro 05:08 Making R&D decisions 10:11 Clinical trials 24:59 Drug pricing 32:43 Stimulating more R&D 45:16 Pros and cons of US healthcare 58:20 New pharma business models 01:05:53 Stripe + enterprises 01:07:00 China 01:16:31 Generics 01:22:37 GLP-1s 1:37:43 r/Peptides 01:41:25 LillyDirect 01:46:35 Why do investors love LLY?
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Kalpit Champanery retweetledi
Two big milestones today:
1. First customer that closed in under 24 hours
2. Three new customers signed (in one day)
LFG 🔥🔥🔥
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@joedevon I also got excited with all the update. I'm yet to try checkpoint, resume and new context manager
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That was my initial reaction because it felt visually very appealing compared to the previous version, it has a cool little table that show in for the command and out for the terminal output.
But after using it for a bit the enthusiasm has been tamped down. No copy button on reply. Some rigidity. It still needs work
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I also have seen this for the first time!
seems like a recent change (and me not leveraging claude so much in my past couple of days)
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TIL that when you do "/context" in CC, it fills up your context window by at least 1k tokens, not sure if its just me bcz of my claude_md file or its just the output of the /context that fills up the context window but in either case its better to use statusline functionality
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I'll have to see that mobile one, to run it on my fold 6
Sam Altman@sama
gpt-oss is out! we made an open model that performs at the level of o4-mini and runs on a high-end laptop (WTF!!) (and a smaller one that runs on a phone). super proud of the team; big triumph of technology.
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@coderabbi Yeah is great. I was taking more in terms of when you want to use LLMs to return you structured output you night want to use with json or xml format prompt that has the output schema.
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@ckalpit I haven't even gone the json route, was being facetious about XML, honestly. I've been nothing less than thrilled with the output that I'm getting with Claude Code Driver-Navigator pairing, a few custom / commands, and judicious use of sub-agents.
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Why is no one talking about XML prompting??
Oh, yeah, because XML.
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@evincc_ Ive seen it, seems like too much... have you used it?
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@ckalpit Not sure if you're open to MCPs, but this one is pretty good.
github.com/modelcontextpr…
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Has anyone successfully built a claude code system where at the end of each session it can store the summary of the session and todos and then at the beginning of each session it can read last session's summary
I am trying to build one
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Hey @AnthropicAI, I don't know how going from version 1.0.45 to version 1.0.44 is considered "Update" !
@claude_code
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Kalpit Champanery retweetledi
@ckalpit Yeah, saw them too. MCP does not have any use case besides some distrustful middle manager querying GitHub in natural language, because he/she/they are technically rusty. Although if adopted, MCP can make it easier to build Knowledge agents.
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I see a lot of chatter about MCP being the next big thing, but I am not really sold on it yet!
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@RaghavKhamar I saw a bunch of videos and all they were showing is github mcp and browser use, and I don't find it that much useful tbh
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@ckalpit You mean, devs are using MCP over git commands? That's bizarre.
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